Synergistic effects of a lytic Salmonella bacteriophage cocktail and selected antimicrobial agents on Salmonella enterica serovar Enteritidis [0.03%]
溶菌沙门氏菌噬菌体联合几类抗菌剂对鸡胚Salmonella Enteritidis的协同作用研究
M Pouladzadeh,S M Hosseini,A Mir-Mohammad Sadeghi
M Pouladzadeh
Salmonella Enteritidis is a major causative agent of gastroenteritis and foodborne illnesses, posing significant therapeutic challenges due to the rise of multidrug-resistant (MDR) strains. The increasing prevalence of resistant isolates hi...
Machine learning-guided discovery of spirocyclic inhibitors targeting Mycobacterium tuberculosis FtsZ [0.03%]
机器学习引导发现螺环型抑制剂靶向分枝杆菌细胞分裂蛋白FtsZ
Rahul Singh,Vivek Dhar Dwivedi,Garima Chouhan
Rahul Singh
Tuberculosis continues to pose serious threats to global public health and calls for the design of new drugs that can target key bacterial proteins. This research used an integrated approach involving computational techniques to discover ne...
Multifunctional bioactivity of Echinops niveus: Antimicrobial, antioxidant, and cytotoxic evaluation [0.03%]
刺芹的多功能生物活性：抗菌、抗氧化和细胞毒性评价
Syeda Anber Zahra,Sumreen Dawood,Javed Iqbal et al.
Syeda Anber Zahra et al.
Medicinal plants remain a vital source of new therapeutic agents, yet many species remain underexplored. Echinops niveus Wall. ex Royle, a member of the Asteraceae family, has not been comprehensively evaluated for multifunctional bioactivi...
Molecular epidemiology and clinical course of PVL-positive MRSA CC398 infections [0.03%]
PVL阳性MRSACC398的分子流行病学和临床过程
Kristýna Brodíková,Ivana Koláčková,Miroslava Htoutou Sedláková et al.
Kristýna Brodíková et al.
Methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 398 (CC398) carrying the lukS-PV/lukF-PV genes encoding the Panton-Valentine leukocidin (PVL) production is emerging as a concerning pathogen in the Czech Republic and Europe...
Proline treatment improves salinity tolerance in the green microalga Dunaliella sp. by altering carbon partitioning and inducing metabolites accumulation [0.03%]
脯氨酸处理通过改变碳分配并诱导代谢物积累来提高绿微藻Dunaliella sp.的耐盐性
Fahimeh Sargolzaei,Alireza Einali
Fahimeh Sargolzaei
The role of proline (Pro) in salinity tolerance of Dunaliella sp. cells was investigated by studying biochemical responses and antioxidant enzyme activities. Algal cells grown in 1, 2, and 3 M NaCl concentrations in the exponential growth p...
B Říhová
B Říhová
Anti-Candida albicans and anti-virulence activities of vaginal Lactobacillus strains from asymptomatic women: phenotypic characterization and prediction of antimicrobial peptide gene clusters [0.03%]
来自无症状妇女阴道乳杆菌菌株的抗白色念珠菌和抗菌活性：表型特征及抗菌肽基因簇预测分析
Carmem Duarte Lima Campos,Camila Itapary Dos Santos,Ennio Patrezzi Sousa Costa et al.
Carmem Duarte Lima Campos et al.
Vulvovaginal candidiasis (VVC) is a prevalent mucosal infection primarily caused by Candida albicans, affecting up to 75% of women of reproductive age. VVC therapeutic management is increasingly challenged by antifungal resistance, host tox...
The integrative role of the microbiome in systemic immuno-inflammatory aberrations [0.03%]
肠道菌群在系统性免疫炎症异常中的整合作用
Ying Liu,Chenyang Liu,Xingmei Yin et al.
Ying Liu et al.
The human immune system maintains a delicate balance between protective immunity and self-tolerance. Disruption of this equilibrium leads to immune-mediated diseases (IMDs), a heterogeneous group of disorders including autoimmune, allergy, ...
Gnotobiology: from 19th-century global foundations to 21st-century omics - six decades of Czech contribution to microbiome research [0.03%]
无菌生物学：从19世纪的全球基础到21世纪的组学——捷克微生物组研究六十年的贡献
Helena Tlaskalová-Hogenová,Tomáš Hrnčíř,Renata Štěpánková et al.
Helena Tlaskalová-Hogenová et al.
Gnotobiology, from the Greek gnotos (meaning 'known') and bios (meaning 'life'), is a research discipline that uses organisms with a defined microbiological status to study the interaction between hosts and microbes. This review traces six ...
Bioactivity and biosynthetic insights into Penicillium brefeldianum BPSRJ7, an endophyte associated with the ethnomedicinal orchid Dendrobium chrysotoxum lindl [0.03%]
产派利霉素青霉菌株BPSRJ7的生物活性及次级代谢产物合成机制研究——基于民族药用水斛兰草(Dendrobium chrysotoxum lindl.)内生真菌的作用与发现
Bishal Pun,Santa Ram Joshi
Bishal Pun
Endophytic fungi are recognized as prolific sources of bioactive secondary metabolites with therapeutic potential, often complementing the pharmacological properties of their host plants. Dendrobium chrysotoxum, an ethnomedicinal orchid, ha...