Marine-derived Aspergillus sp.-mediated biosynthesis of silver nanoparticles with antioxidant activity and immunomodulatory apoptosis induction in melanoma cells [0.03%]
海洋来源的曲霉介导的银纳米颗粒的生物合成及其抗氧化活性和诱导黑色素瘤细胞免疫调制型凋亡的作用研究
Mervat G Hassan,Somaya Sh Youssef,Mohamed A Abdelmonem et al.
Mervat G Hassan et al.
In this work, we use a fungal isolate, Aspergillus sp. SO23, derived from a marine sponge collected from the coast of Hurghada, Egypt, to isolate, identify, and biosynthesis silver nanoparticles (Ag NPs). Following molecular and visual iden...
Pichia kudriavzevii yeast cell wall as a novel source of β-glucan: Extraction, characterization, and prebiotic functionality [0.03%]
解脂耶罗华氏酵母菌细胞壁作为β-葡聚糖新来源：提取、定性与益生元功能
Buse Dengiz,Zehranur Yuksekdag,Seniha Selcen Babaoglu-Aydas et al.
Buse Dengiz et al.
In this study, β-glucan extraction was optimized from the Pichia kudriavzevii M10 strain, which was randomly selected from five yeast candidates (M5, M10, M13, M16, and M57). The goal was not only to maximize extraction yield but also to t...
Microbiome alterations in healthy pregnancy and pregnancy disorders in association with autoimmune diseases [0.03%]
与自身免疫性疾病相关的健康妊娠和妊娠并发症的微生物组变化
Fatma El-Saeed El-Demerdash,Osama A Mohammed,Hend H Mohamed et al.
Fatma El-Saeed El-Demerdash et al.
Pregnancy induces significant alterations in the maternal microbiome, which are critical for fetal development and maternal health. Gynecological diseases, along with infertility, have increased due to excessive personal care product usage,...
Microbe-based fluorescent sensor composite for drug delivery and hepatocellular carcinoma suppression [0.03%]
用于药物输送和肝细胞癌抑制的微生物荧光传感器复合材料
Li Li,Xianzhe Lu,Liudan Liang et al.
Li Li et al.
Hepatocellular carcinoma (HCC) remains a major clinical challenge due to its late diagnosis and poor prognosis. To address these limitations, we developed a novel gefitinib derivative (DCQ-Me) and integrated it into a multifunctional fluore...
Antimicrobial activity of gentamicin-conjugated monometallic and bimetallic nanoparticles against multidrug-resistant Klebsiella pneumoniae strains [0.03%]
含金单金属和双金属纳米颗粒结合吉他霉素对多药耐药肺炎克雷伯氏菌的抗菌活性研究
Samira Zakeer,Mariam E Amin,Gharieb S El-Sayyad et al.
Samira Zakeer et al.
Multidrug-resistant Klebsiella pneumoniae (MDR-KP) poses a significant clinical challenge due to limited therapeutic options and high mortality. This study investigated the antimicrobial efficacy of gamma-irradiation-synthesized gentamicin-...
Enhancing okra tolerance to salinity stress: role of PGPR and antioxidant enzymes [0.03%]
植物根际促生菌和抗氧化酶活对锦葵耐盐性的影响研究
Catherine Jose,Subramaniyan S,Sandhia G S
Catherine Jose
Salinity stress is a major constraint on global crop productivity, necessitating sustainable strategies to enhance plant resilience. Plant growth-promoting rhizobacteria (PGPR) with 1-aminocyclopropane-1-carboxylate (ACC) deaminase activity...
Gut allies against metabolic disorders: the therapeutic promise of probiotics [0.03%]
肠道盟友对抗代谢性疾病——益生菌的治疗前景
Tolulope Joshua Ashaolu,Thanh-Do Le
Tolulope Joshua Ashaolu
Physalis peruviana and Lactobacillus lysates as modulators of lipid metabolism and oxidative stress: a natural alternative to statin therapy [0.03%]
用 Physalis peruviana 和乳酸菌提取物调节脂质代谢和氧化应激：一种替代他汀疗法的自然方法
Manal Mused Almatrafi,Alaa H Nada,Ahmed S Doghish et al.
Manal Mused Almatrafi et al.
Hyperlipidemia is a major modifiable risk factor for atherosclerosis and coronary heart disease. Although effective, current pharmacological interventions such as statins are often limited by adverse effects, including muscular pain, gastro...
Therapeutic advances in the fight against microbial resistance: innovative strategies and future challenges [0.03%]
抗微生物药物耐药性战疫中的治疗进展：创新策略与未来挑战
Jonathan Mandú de Araújo,Alícia Natalie Silva Dos Santos,Bruno José da Silva Bezerra et al.
Jonathan Mandú de Araújo et al.
Antimicrobial Resistance (AMR) is characterized by the reduced effectiveness of antibiotics due to the adaptation of microorganisms, which limits therapeutic options and increases the severity of infections. This paper aims to discuss thera...
Structure-guided discovery and validation of a potent RamR inhibitor targeting efflux-mediated multidrug resistance in Salmonella typhimurium [0.03%]
结构指导的RamR抑制剂发现与验证：靶向沙门氏菌外排诱导型多药抗性蛋白
Gopal Prasad Agrawal,Md Shamsher Alam,Faisal Alotaibi et al.
Gopal Prasad Agrawal et al.
The emergence of multidrug-resistant (MDR) strains of Salmonella typhimurium (S. typhimurium) causes a significant global health challenge and underscores the need to develop potential antimicrobial agents. Here, we considered RamR, the maj...