Green synthesis and antifungal evaluation of Moringa oleifera-mediated iron oxide nanoparticles against Rhizopus stolonifer infecting Coleus scutellarioides [0.03%]
辣根树生物合成铁氧化物纳米颗粒的绿色制备及抗菌活性评价
Sadaf Anwaar,Maryam Bibi,Ansa Muqaddas et al.
Sadaf Anwaar et al.
Fungal diseases reduce the ornamental and medicinal value of Coleus scutellarioides, while reliance on synthetic fungicides raises concerns regarding resistance development and environmental safety. Green synthesis of iron oxide nanoparticl...
From symptom management to immune prevention: a comprehensive review of chikungunya treatment and vaccine development [0.03%]
从对症治疗到免疫预防——寨卡病毒的治疗方法及疫苗研发进展综述
Xin Li,Zijun Yuan,Junjie Ni et al.
Xin Li et al.
Chikungunya is an acute illness caused by the chikungunya virus (CHIKV) and spread by Aedes mosquitoes. It has now been reported in over 100 countries, posing an increasing public health challenge. The disease presents with a range of sympt...
Gramine disrupts quorum sensing and biofilm formation of Pseudomonas aeruginosa: An integrated experimental and computational analysis [0.03%]
基于实验和计算的综合分析显示Gramine可通过干扰赤脓菌的群体感应及生物被膜形成来抑制其生长
Paramita Pakhira,Sampathkumar Ranganathan,Paramanantham Parasuraman et al.
Paramita Pakhira et al.
Bacterial resistance towards antibiotics has become a major problem worldwide. Bacteria become more resistant towards available antibiotics due to quorum sensing and biofilm formation. Alkaloids exhibited potential anti-bacterial activity. ...
Host-pathogen interactions during ESKAPE-mediated urinary tract infections and ventilator-associated pneumonia: a review [0.03%]
ESKAPE所致尿路感染和呼吸机相关肺炎的宿主病原菌相互作用研究进展
Tejpal Sharma,Pankaj Chandley
Tejpal Sharma
Antimicrobial resistance (AMR) represents one of the most critical healthcare concerns worldwide, specifically amplified by the ESKAPE pathogens, which represent the six most nosocomial pathogens: Enterococcus faecium, Staphylococcus aureus...
Isolation, characterization, and proof of concept evaluation of serially adapted bacteriophages against multidrug-resistant Escherichia coli [0.03%]
分离、表征和评估针对多重耐药的大肠杆菌系列适应性噬菌体的概念证明
Varun Rathi,Prakash R Nayak,Namdeo R Bulbule et al.
Varun Rathi et al.
This study was conducted to test serially passaged bacteriophages for combating multidrug-resistant Escherichia coli strains and to address the urgent need for sustainable alternatives to antibiotics. Bacteriophages were isolated from diver...
Lactobacillus strains in the prevention and disruption of antimicrobial-resistance in pathogenic microbial biofilms: a review of mechanisms and clinical perspective [0.03%]
乳酸菌菌株在预防和破坏病原微生物生物被膜抗生素耐药性方面的应用：机制与临床视角综述
Maedeh Kiani,Mahtab Mehboodi,Hadis Khanbabaie et al.
Maedeh Kiani et al.
The growing prevalence of antibiotic resistance, coupled with the heightened drug tolerance exhibited by biofilm-associated infections, represents a major public health challenge and demands the development of innovative therapeutic interve...
Synergistic effects of a lytic Salmonella bacteriophage cocktail and selected antimicrobial agents on Salmonella enterica serovar Enteritidis [0.03%]
溶菌沙门氏菌噬菌体联合几类抗菌剂对鸡胚Salmonella Enteritidis的协同作用研究
M Pouladzadeh,S M Hosseini,A Mir-Mohammad Sadeghi
M Pouladzadeh
Salmonella Enteritidis is a major causative agent of gastroenteritis and foodborne illnesses, posing significant therapeutic challenges due to the rise of multidrug-resistant (MDR) strains. The increasing prevalence of resistant isolates hi...
Machine learning-guided discovery of spirocyclic inhibitors targeting Mycobacterium tuberculosis FtsZ [0.03%]
机器学习引导发现螺环型抑制剂靶向分枝杆菌细胞分裂蛋白FtsZ
Rahul Singh,Vivek Dhar Dwivedi,Garima Chouhan
Rahul Singh
Tuberculosis continues to pose serious threats to global public health and calls for the design of new drugs that can target key bacterial proteins. This research used an integrated approach involving computational techniques to discover ne...
Multifunctional bioactivity of Echinops niveus: Antimicrobial, antioxidant, and cytotoxic evaluation [0.03%]
刺芹的多功能生物活性：抗菌、抗氧化和细胞毒性评价
Syeda Anber Zahra,Sumreen Dawood,Javed Iqbal et al.
Syeda Anber Zahra et al.
Medicinal plants remain a vital source of new therapeutic agents, yet many species remain underexplored. Echinops niveus Wall. ex Royle, a member of the Asteraceae family, has not been comprehensively evaluated for multifunctional bioactivi...
Molecular epidemiology and clinical course of PVL-positive MRSA CC398 infections [0.03%]
PVL阳性MRSACC398的分子流行病学和临床过程
Kristýna Brodíková,Ivana Koláčková,Miroslava Htoutou Sedláková et al.
Kristýna Brodíková et al.
Methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 398 (CC398) carrying the lukS-PV/lukF-PV genes encoding the Panton-Valentine leukocidin (PVL) production is emerging as a concerning pathogen in the Czech Republic and Europe...