Vaccines, virucides and drugs against HIV/AIDS: hopes and optimisms for the future [0.03%]
艾滋病疫苗、抗病毒药物和治疗药品：未来的希望与乐观态度
A A Al-Jabri,F Q Alenzi
A A Al-Jabri
More than 25 million lives have been claimed by AIDS and 33.2 million people are estimated to have HIV, the majority of which are living in the underdeveloped countries. Failed tests on vaccines, virucides and complete virus eradication hav...
Awareness and attitudes about HIV among pregnant women in Aksu, northwest China [0.03%]
中国西北阿克苏地区孕产妇艾滋病知晓及态度调查
Rena Maimaiti,Rune Andersson
Rena Maimaiti
The Xinjiang Uyghur Autonomous Region has a firmly established HIV epidemic among its intravenous drug user (IDU) population. Local sex workers were also found to be positive in 1998. A descriptive, cross-sectional survey of knowledge about...
Harnessing pharmacogenomics to tackle resistance to the "nucleoside reverse trancripatse inhibitor" backbone of highly active antiretroviral therapy in resource limited settings [0.03%]
利用药物基因组学在资源有限地区应对高活性抗逆转录病毒疗法中的“核苷逆转录酶抑制剂”耐药问题
Misaki Wayengera,Henry Kajumbula,Wilson Byarugaba
Misaki Wayengera
Background: The sustainable use of HAART within the sub-Saharan and other developing world settings faces the emerging challenge of drug resistance. Nucleoside reverse transcriptase inhibitors (NRTI) form the backbone of ...
Liver enzyme alterations in HCV-monoinfected and HCV/HIV-coinfected patients [0.03%]
HCV单感染和HCV/HIV共感染者肝酶改变的区别
Klaus Langohr,Arantza Sanvisens,Daniel Fuster et al.
Klaus Langohr et al.
Hepatitis C virus (HCV) is the most common blood-borne infection in developed countries and co-infection with the Human Immunodeficiency Virus (HIV) is frequent in individuals with history of injecting drug use (IDU).We aimed to analyze liv...
High treatment success rates when switching to once daily nevirapine containing antiretroviral therapy [0.03%]
换用奈韦拉平每日一次抗逆转录病毒治疗的高治愈率研究
Andrew Benzie,Brett Marett,Nicola E Mackie et al.
Andrew Benzie et al.
Introduction: Two recent studies have highlighted low rates of virological response to once daily nevirapine containing combination antiretroviral therapy (CART) in treatment naïve HIV-1 infected subjects. ...
Pharmacokinetics of acetyl-L-carnitine given in single or multiple doses to HIV-1 Infected patients with toxic peripheral polyneuropathy [0.03%]
单次或多次给予乙酰左卡尼丁治疗HIV-1感染外周神经毒性的药动学研究
C Herzmann,S J Whiting,M Thomas et al.
C Herzmann et al.
The use of nucleoside reverse transcriptase inhibitors in the treatment of HIV infection is associated with antiretroviral toxic polyneuropathy (ATN). Previous studies suggest that long term treatment with Acetyl-L-carnitine (ALCAR) 1.5 gra...
Clinical progression rates by CD4 cell category before and after the initiation of combination antiretroviral therapy (cART) [0.03%]
启动高效抗逆转录病毒治疗前后各CD4细胞组别的临床病程进展速度
Marguerite Guiguet,Kholoud Porter,Andrew Phillips et al.
Marguerite Guiguet et al.
Objective: Rates of AIDS defining event (ADE), serious ADE and death by CD4 and HIV RNA categories before and after combination antiretroviral therapy (cART) initiation are lacking for high CD4 counts. ...
Strengthening healthcare capacity through a responsive, country-specific, training standard: the KITSO AIDS training program's support of Botswana's national antiretroviral therapy rollout [0.03%]
通过及时的、具有国家针对性的标准培养医疗能力：KITSO艾滋病教育项目的国家抗逆转录病毒治疗计划支持以国家为特定对象
Christine Bussmann,Philip Rotz,Ndwapi Ndwapi et al.
Christine Bussmann et al.
In parallel with the rollout of Botswana's national antiretroviral therapy (ART) program, the Botswana Ministry of Health established the KITSO AIDS Training Program by entering into long-term partnerships with the Botswana-Harvard AIDS Ins...
"Contagious love": a qualitative study of the couple relationships of ten AIDS carriers [0.03%]
"具有感染力的爱":艾滋病病毒感染者的伴侣关系定性研究
Doron Hadas,Teichner Noa,Grey Adi et al.
Doron Hadas et al.
The qualitative study in this article portrays the couple relationship among AIDS carriers, based on Sternberg's triangular love theory (involving domains of intimacy, passion and commitment). The central study hypothesis is that certain co...
Infection of CD8+CD45RO+ memory T-cells by HIV-1 and their proliferative response [0.03%]
HIV-1感染的记忆T细胞(_CD8_+_CD45RO_+)及其增殖反应
Naveed Gulzar,Sowyma Balasubramanian,Greg Harris et al.
Naveed Gulzar et al.
CD8+ T-cells are involved in controlling HIV-1 infection by eliminating infected cells and secreting soluble factors that inhibit viral replication. To investigate the mechanism and significance of infection of CD8+ T-cells by HIV-1 in vitr...