Emilio Moreno-Millán,Agustin Molina-Morales,Ignacio Amate-Fortes
Emilio Moreno-Millán
Objectives: The main objective of this study is to verify the existence of a direct relation between age, ageing and hospital resources utilization. Metho...
The Six Item Cognitive Impairment Test (6-CIT) as a screening test for dementia: comparison with Mini-Mental State Examination (MMSE) [0.03%]
简易认知功能筛查量表(6-CIT)与简易智能精神状态检查(MMSE)在痴呆筛选中的比较研究
Ajaya K Upadhyaya,Magesh Rajagopal,Tim M Gale
Ajaya K Upadhyaya
Background: The UK national Dementia Strategy clearly outlines a case for early detection and diagnosis of dementia. There is thus a need for a brief screening test for dementia in primary care, which can be administered ...
Comparative Study
Current aging science. 2010 Jul;3(2):138-42. DOI:10.2174/1874609811003020138 2010
Molecular mechanisms in aging and current strategies to counteract sarcopenia [0.03%]
衰老的分子机制及对抗少肌症的当前策略
Kunihiro Sakuma,Akihiko Yamaguchi
Kunihiro Sakuma
Sarcopenia, the progressive loss of muscle mass with age, is characterized by a deterioration of muscle quantity and quality leading to a gradual slowing of movement and a decline in strength and power. Sarcopenia is a highly significant pu...
Sofía Rodríguez,Maria Eriksson
Sofía Rodríguez
The molecular mechanisms that cause physiological aging are still not completely understood, most likely because of the complex nature of the aging process. Recent discoveries on segmental progeroid syndromes emphasize the importance of stu...
Gwendolen E Haley,Frederique Berteau-Pavy,Byung Parkv et al.
Gwendolen E Haley et al.
Previously we reported that apolipoprotein E (ApoE) epsilon4 negatively affects performance in the novel-image-novel-location (NINL) object recognition test in healthy non-demented elderly human study participants. In this study, the partic...
Short- and long-term survival of nonsurgical intensive care patients and its relation to diagnosis, severity of disease, age and comorbidities [0.03%]
非手术重症监护患者的短期和长期生存率及其与诊断、疾病严重程度、年龄和合并症的关系
Peter A Kaufmann,Karl H Smolle,Guenter J Krejs
Peter A Kaufmann
Objective: To identify variables associated with mortality in the ICU and 1 year following discharge. Design: Prospective observational...
Translational pharmacology in aging men with benign prostatic hyperplasia: molecular and clinical approaches to alpha1-adrenoceptors [0.03%]
用于老年良性前列腺增生患者的药物翻译药理学：α1肾上腺素受体的分子和临床方法
Yoshiyuki Kojima,Yasue Kubota,Shoichi Sasaki et al.
Yoshiyuki Kojima et al.
Benign prostatic hyperplasia (BPH) occurs in over 50% of men over 60 years of age, most of whom have lower urinary tract symptoms (LUTS). The incidence of BPH appears to be increasing due to the increased longevity of men. LUTS associated w...
Relationship of dietary habits and obesity to oxidative stress in Palauan people: compared with Japanese and Mongolian people [0.03%]
帕劳人饮食习惯、肥胖与氧化应激的关系及其与日本人和蒙古人的比较研究
Fumio Komatsu,Yasuo Kagawa,Terue Kawabata et al.
Fumio Komatsu et al.
The Republic of Palau belongs to Micronesia, and obese people and lifestyle-related diseases are prevalent there. We investigated the relationship of dietary habits and obesity to oxidative stress in Palauan people, as compared with those o...
Comparative Study
Current aging science. 2009 Dec;2(3):214-22. DOI:10.2174/1874609810902030214 2009
Pathology associated memory deficits in Swedish mutant genome-based amyloid precursor protein transgenic mice [0.03%]
基于瑞典突变基因的APP转基因小鼠源性淀粉样前体蛋白相关病理性损害致学习记忆障碍
Brian J Hock,K Matthew Lattal,Laura Shapiro Kulnane et al.
Brian J Hock et al.
To gain insight into the relationship between pathological alterations and memory deficits observed in Alzheimer's disease (AD), a number of amyloid precursor protein (APP) transgenic animal models have been generated containing familial AD...
Comparing age effects in normally and extremely highly educated and intellectually engaged 65 - 80 year-olds: potential protection from deficit through educational and intellectual activities across the lifespan [0.03%]
常人与才智超群的长寿老人的认知老化效应比较：终身教育和智力活动对认知缺损的潜在保护作用
Vera Schumacher,Mike Martin
Vera Schumacher
Education and cognitive activity have been suggested to protect against cognitive decline in old age. However, little is known about the long-term effects of extremely high levels of education and intellectual activity across the lifespan. ...
Comparative Study
Current aging science. 2009 Dec;2(3):200-4. DOI:10.2174/1874609810902030200 2009