Systemic administration of tolerogenic dendritic cells ameliorates murine inflammatory arthritis [0.03%]
口服耐受性树突状细胞改善小鼠炎性关节炎
Louise J Healy,Helen L Collins,Stephen J Thompson
Louise J Healy
The expression of various cell surface molecules and the production of certain cytokines are important mechanisms by which dendritic cells (DC) are able to bias immune responses. This paper describes the effects of the inflammatory cytokine...
Incidence of Rheumatoid Arthritis in the Southern part of Denmark from 1995 to 2001 [0.03%]
丹麦南部1995年至2001年期间类风湿性关节炎的患病率
Jens K Pedersen,Anders J Svendsen,Kim Hørslev-Petersen
Jens K Pedersen
We estimated the incidence of rheumatoid arthritis in the southern part of Denmark from 1995 to 2001. At a rheumatology hospital serving a population of about 200 000 people over the age of 15, medical records were scrutinized. As case defi...
Infections are not increased in scleroderma compared to non-inflammatory musculoskeletal disorders prior to disease onset [0.03%]
与非炎症性肌肉骨骼疾病相比，硬皮病发病前的感染率并未增加
Janet E Pope,Jodi L Goodwin,Janine M Ouimet et al.
Janet E Pope et al.
The etiology of scleroderma (SSc) is unknown; immunogenic stimuli such as infections and vaccinations could theoretically be risk factors for scleroderma. Our objective was to assess the relationship between viral and bacterial infections, ...
Complementary and alternative medicine use in musculoskeletal disorders: does medical skepticism matter? [0.03%]
医学怀疑论在肌骨系统疾病中的补充和替代医学使用上起到什么作用？
Elizabeth K Wiley-Exley,Thelma J Mielenz,Edward C Norton et al.
Elizabeth K Wiley-Exley et al.
Medical skepticism is the reservation about the ability of conventional medical care to significantly improve health. Individuals with musculoskeletal disorders seeing specialists usually experience higher levels of disability; therefore it...
Rituximab for refractory rheumatoid arthritis: a 24-week open-label prospective study [0.03%]
利妥昔单抗治疗难治性类风湿关节炎的疗效观察一项24周开放前瞻性研究
Ling Yin Ho,Chi Chiu Mok,Chi Hung To et al.
Ling Yin Ho et al.
Objectives: To study the efficacy of rituximab in active rheumatoid arthritis (RA) patients refractory to disease modifying anti-rheumatic drugs (DMARDs) including the tumor necrosis factor (TNF)-alpha antagonists. ...
Risk factors for osteoporosis and fractures in postmenopausal women between 50 and 65 years of age in a primary care setting in Spain: a questionnaire [0.03%]
西班牙初级保健机构中50至65岁绝经后妇女骨质疏松和骨折的危险因素：基于问卷的调查
Maria Luz Rentero,Cristina Carbonell,Marta Casillas et al.
Maria Luz Rentero et al.
Introduction: Osteoporosis (OP) is a major, highly prevalent health problem and osteoporosis-related fractures account for high morbidity and mortality. Therefore, prevention and early detection of osteoporosis should str...
Ori Elkayam,Irena Litinsky,David Levartovsky et al.
Ori Elkayam et al.
Objectives: Tumor necrosis factor alpha (TNF-α ) therapy has been implicated in the development of autoimmune diseases. Our aim was to describe three patients with spondyloarthropathies who responded to infliximab, a chi...
Work disability in scleroderma is greater than in rheumatoid arthritis and is predicted by high HAQ scores [0.03%]
硬皮病的劳动能力障碍高于类风湿关节炎，并且由HAQ评分高预测
Janine M Ouimet,Janet E Pope,Iris Gutmanis et al.
Janine M Ouimet et al.
Objectives: To estimate the frequency of work disability (WD) in a cohort of patients with Systemic Sclerosis (SSc) vs an internal control group of patients with rheumatoid arthritis (RA) with a known high frequency of WD...
Resistance to rituximab therapy and local BAFF overexpression in Sjögren's syndrome-related myoepithelial sialadenitis and low-grade parotid B-cell lymphoma [0.03%]
Sjögren综合征相关的肌上皮性唾液腺炎和低级别腮腺B细胞淋巴瘤对利妥昔单抗治疗的抵抗及局部BAFF过表达
Luca Quartuccio,Martina Fabris,Massimo Moretti et al.
Luca Quartuccio et al.
Objective: B-cell expansion is a key feature of Sjögren's syndrome (SS). Accordingly, several studies have reported the benefits of B-cell depletion with anti-CD20 monoclonal antibody (Rituximab) in the treatment of glan...
Cigarette smoking, birthweight and osteoporosis in adulthood: results from the hertfordshire cohort study [0.03%]
吸烟、出生体重与成年期骨质疏松症——赫特福德郡队列研究结果分析
M M Moinuddin,K A Jameson,H E Syddall et al.
M M Moinuddin et al.
We looked for interaction between early environment and adult lifestyle in determination of bone mineral content (BMC) and bone mineral density (BMD) among 498 men and 468 women for whom birth records were available. Participants completed ...