Expression of DeltaF508 Cystic Fibrosis Transmembrane Regulator (CFTR) Decreases Membrane Sialylation [0.03%]
DeltaF508囊性纤维化跨膜调节器(CFTR)的表达降低膜岩藻糖基化水平
Amrita Dosanjh,Elaine A Muchmore
Amrita Dosanjh
Chronic colonization and infection of the lung with Pseudomonas aeruginosa is a major cause of morbidity and mortality in cystic fibrosis (CF) patients. Imundo, et al. determined that CF cells had a higher concentration of an asialoganglios...
Identification and Measurement of Carbonic Anhydrase-II Molecule Numbers in the Rat Carotid Body [0.03%]
大鼠颈动脉体中碳酸酐酶-Ⅱ分子数量的鉴定与测定
Guglielmo Di Tano,Claudia Petrarca,Gerardo Bosco et al.
Guglielmo Di Tano et al.
Carbonic anhydrase (CA) in the carotid body (CB) plays an important role in the maintenance of blood PO2 and PCO2/pH homeostasis by regulating ventilation. It has been observed that the activity of CA in the rabbit CB is stronger under hypo...
Utility of d-dimer in the diagnosis of patients with chronic thromboembolic pulmonary hypertension [0.03%]
D-二聚体在慢性血栓性肺动脉高压诊断中的应用价值
Vichaya Arunthari,Charles D Burger
Vichaya Arunthari
Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is an important cause of severe pulmonary hypertension (PH). D-dimer, a degradation product of fibrin, has been used as a marker for various diseases. In p...
Josep Lluis Heredia
Josep Lluis Heredia
Tiotropium bromide is a once-daily inhaled anticholinergic bronchodilator. It works by blocking the muscarinic receptors in airway smooth muscle. Tiotropium has a wide therapeutic margin, due to its poor gastrointestinal absorption and its ...
Bone mineral density and secondary hyperparathyroidism in pulmonary hypertension [0.03%]
肺动脉高压患者的骨密度和继发性甲状旁腺功能亢进症的风险因素分析
Silvia Ulrich,Martin Hersberger,Manuel Fischler et al.
Silvia Ulrich et al.
Background: Low bone mineral density (BMD) is common in chronic lung diseases and associated with reduced quality of life. Little is known about BMD in pulmonary hypertension (PH). ...
Correlation of Plasma Protein Carbonyls and C-Reactive Protein with GOLD Stage Progression in COPD Patients [0.03%]
蛋白质 carbonyls 和 C-反应蛋白与慢性阻塞性肺疾病患者 GOLD 分期进展的相关性研究
Yessica D Torres-Ramos,María L García-Guillen,Ivonne M Olivares-Corichi et al.
Yessica D Torres-Ramos et al.
Oxidative stress plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). To investigate the correlation between the progression of COPD and plasma biomarkers of chronic inflammation and oxidative injury,...
New pharmacologic perspectives in pneumology: beclomethasone-formoterol extrafine [0.03%]
肺科的新的药理学展望：倍氯米松-福莫特罗超细颗粒制剂
Pierluigi Paggiaro
Pierluigi Paggiaro
International asthma guidelines have recently focused on the concept of , which is the main outcome to reach and maintain in the long term management. Asthma control is associated with several positive consequences, both in terms of quality...
New concepts in the invasive and non invasive evaluation of remodelling of the right ventricle and pulmonary vasculature in pulmonary arterial hypertension [0.03%]
肺动脉高压患者右心室及肺血管重构的无创与有创评估新概念
Enric Domingo,Rio Aguilar,Manuel López-Meseguer et al.
Enric Domingo et al.
Pulmonary arterial hypertension (PAH) is a rare fatal disease defined as a sustained elevation of pulmonary arterial pressure to more than 25 mmHg at rest, with a mean pulmonary-capillary wedge pressure and left ventricular enddiastolic pre...
Indacaterol, A Novel Once Daily Inhaled beta2-Adrenoreceptor Agonist [0.03%]
茚达特罗：一种新型的每日一次吸入给药的选择性长效β₂肾上腺素受体激动剂
Jorge Roig,Rosana Hernando,Ramon Mora
Jorge Roig
In this article we will review the role of long acting beta2-adrenoreceptor agonists and long-acting muscarinic agents in the management of airflow obstruction. We will then focus our attention on indacaterol, one of the new once daily inha...
Monitoring Patient/Ventilator Interactions: Manufacturer's Perspective [0.03%]
从医疗器械生产商角度看患者/呼吸机交互监测
Gerard Evers,Carl Van Loey
Gerard Evers
The introduction of reduced and more powerful electronics has allowed the transition of medical equipment such as respiratory support devices from the hospital to the patient's home environment. Even if this move could be beneficial for the...