Backbone and methyl side-chain resonance assignments of the Fab fragment of adalimumab [0.03%]
阿达木单抗Fab段的主链及甲基侧链共振峰指认
Muzaddid Sarker,Yves Aubin
Muzaddid Sarker
Adalimumab is a therapeutic monoclonal antibody developed to target human TNF an important mediator of immune-mediated inflammatory diseases such as rheumatoid arthritis, amongst others. The 48 kDa Fab fragment of adalimumab was produced in...
Assignment of the Lassa virus transmembrane domain in the prefusion and postfusion states in detergent micelles [0.03%]
阳离子去垢剂胶束中拉沙热病毒融合前后跨膜结构域的定位研究
Patrick M Keating,Jinwoo Lee
Patrick M Keating
Lassa virus (LASV) is the most prevalent member of the arenavirus family and the causative agent of Lassa fever, a viral hemorrhagic fever. Although there are annual outbreaks in West Africa, and recently isolated cases worldwide, there are...
NMR resonance assignment of the cell death execution domain BELL2 from multicellular bacterial signalosomes [0.03%]
来源于多细胞细菌信号体的细胞死亡执行域BELL2的核磁共振共振归属
Loic Delcourte,Corinne Sanchez,Estelle Morvan et al.
Loic Delcourte et al.
Signalosomes are high-order protein machineries involved in complex mechanisms controlling regulated immune defense and cell death execution. The immune response is initiated by the recognition of exogeneous or endogenous signals, triggerin...
Backbone NMR resonance assignments for the VP1u N-terminal receptor-binding domain of the human parvovirus pathogen B19 [0.03%]
人细小病毒B19 VP1u氨基末端受体结合域的骨干核磁共振共振峰指认
Maria Luiza Caldas Nogueira,Renuk Lakshmanan,Gwladys Rivière et al.
Maria Luiza Caldas Nogueira et al.
Parvovirus B19 (B19V) is a human pathogen that is the causative agent of several diseases in infants and adults. Due to a lack of antivirals against this virus, treatment options are limited. The minor capsid protein of B19V has a unique N ...
1H, 13C and 15N backbone resonance assignment of Cel45A from Phanerochaete chrysosporium [0.03%]
Phanerochaete chrysosporium纤维素酶Cel45A的氢-碳-氮化学 shifts背骨共振 assignments
Laura Okmane,Mats Sandgren,Jerry Ståhlberg et al.
Laura Okmane et al.
A glycoside hydrolase family 45 (GH45) enzyme from the white-rot basidiomycete fungus Phanerochaete chrysosporium (PcCel45A) was expressed in Pichia pastoris with 13C and 15N labelling. A nearly complete assignment of 1H, 13C and 15N backbo...
Backbone triple resonance assignments of the dimerization domain of NF-kappaB p52 subunit [0.03%]
NF-κB p52亚基二聚化结构域的骨干三共振 ASSIGNMENT
Sunirmala Sahoo,Nitin Dhaka,Sulakshana P Mukherjee
Sunirmala Sahoo
NF-kappaB is a family of inducible transcription factors playing an important role in immune response in vertebrates. All the five members of the family function as dimers in various combinations. Though all the family members recognize and...
Resonance assignments of cytochrome MtoD from the extracellular electron uptake pathway of sideroxydans lithotrophicus ES-1 [0.03%]
来自铁还原菌Sideroxydans lithotrophicus菌株ES-1细胞色素MtoD的共振分配
Anaísa Coelho,José M Silva,Francesca Cantini et al.
Anaísa Coelho et al.
The contribution of Fe(II)-oxidizing bacteria to iron cycling in freshwater, groundwater, and marine environments has been widely recognized in recent years. These organisms perform extracellular electron transfer (EET), which constitutes t...
NMR chemical shift assignment of Drosophila odorant binding protein 44a in complex with 8(Z)-eicosenoic acid [0.03%]
果蝇嗅觉结合蛋白44a与8(Z)-二十碳烯酸复合物的核磁共振化学位移指认
Myriam L Cotten,Mary R Starich,Yi He et al.
Myriam L Cotten et al.
The odorant binding protein, OBP44a is one of the most abundant proteins expressed in the brain of the developing fruit fly Drosophila melanogaster. Its cellular function has not yet been determined. The OBP family of proteins is well estab...
Backbone and methyl side-chain resonance assignments of the single chain Fab fragment of trastuzumab [0.03%]
曲妥珠单抗单链Fab片段的背骨和甲基侧链共振谱指定
Donald Gagné,James M Aramini,Yves Aubin
Donald Gagné
Trastuzumab is a therapeutic monoclonal antibody developed to target human epidermal growth factor receptor 2 (HER2) present at higher levels in early cancers. Here we report the near complete resonance assignment of trastuzumab-scFab fragm...
1H, 13C, and 15N resonance assignments of the La Motif of the human La-related protein 1 [0.03%]
人相关La蛋白1的La基序的氢-1H、碳-13C和氮-15N共振鉴定
Benjamin C Smith,Robert Silvers
Benjamin C Smith
Human La-related protein 1 (HsLARP1) is involved in post-transcriptional regulation of certain 5' terminal oligopyrimidine (5'TOP) mRNAs as well as other mRNAs and binds to both the 5'TOP motif and the 3'-poly(A) tail of certain mRNAs. HsLA...