The 1H, 15N, and 13C resonance assignments of a single-domain antibody against immunoglobulin G [0.03%]
针对免疫球蛋白G的单结构城抗体的氢-1,氮-15和碳-13共振指派
Vanessa Bezerra de Oliveira Leite,Rafael Alves de Andrade,Fabio Ceneviva Lacerda de Almeida et al.
Vanessa Bezerra de Oliveira Leite et al.
Research on camelid-derived single-domain antibodies (sdAbs) has demonstrated their significant utility in diverse biotechnological applications, including therapy and diagnostic. This is largely due to their relative simplicity as monomeri...
The backbone NMR resonance assignments of the stabilized E. coli β clamp [0.03%]
稳定构象的大肠杆菌β钳夹的骨架核磁共振信号指派
Sam Mahdi,Socheata Lim,Irina Bezsonova et al.
Sam Mahdi et al.
The 81 kDa E. coli β clamp is a ring-shaped head-to-tail homodimer that encircles DNA and plays a central role in bacterial DNA replication by serving as a processivity factor for DNA polymerases and a binding platform for other DNA replic...
NMR 1H, 13C, 15N backbone resonance assignments of 14-3-3ζ binding region of human FOXO3a (residues 1-284) [0.03%]
人FOXO3a(第1-284残基)的14-3-3ζ结合区域的NMR氢-1,碳-13,氮-15主链共振指派
Shota Enomoto,Shoichi Nakatsuka,Tomoya Kuwayama et al.
Shota Enomoto et al.
In tumors, mutation in Ras proteins stimulates a signaling cascade through phosphorylation. Downstream of the cascade, many transcription and translation factors are up- or down-regulated by phosphorylation, leading to cancer progression. T...
1H, 13C and 15N backbone resonance assignment of the calcium-activated EndoU endoribonuclease [0.03%]
EndoU钙离子激活的内切核糖核酸酶的主链共振 assignments
Florian Malard,Fedor V Karginov,Sébastien Campagne
Florian Malard
The catalytic domain of the calcium-dependent endoribonuclease EndoU from Homo sapiens was expressed in E. coli with 13C and 15N labeling. A nearly complete assignment of backbone 1H, 15N, and 13C resonances was obtained, as well as a secon...
Solution NMR backbone resonance assignment of the full-length resistance-related calcium-binding protein Sorcin [0.03%]
溶液NMR完全长度抗药性相关钙结合蛋白Sorcin主链共振指派
Kathleen Joyce Carillo,Yanan He,Qiushi Ye et al.
Kathleen Joyce Carillo et al.
Sorcin is a penta-EF hand calcium-binding protein that confers multidrug resistance in cancer cells. It regulates cellular Ca2+ homeostasis by interacting with calcium channels such as Ryanodine receptor 2 and Sarcoplasmic/endoplasmic retic...
Solution NMR backbone assignment of the N-terminal tandem Zα1-Zα2 domains of Z-DNA binding protein 1 [0.03%]
Z- DNA结合蛋白1的N端串联Zα1-Zα2结构域的溶液NMR主链归属分析
Lily G Beck,Jeffrey B Krall,Parker J Nichols et al.
Lily G Beck et al.
The detection of nucleic acids that are present in atypical conformations is a crucial trigger of the innate immune response. Human Z-DNA binding protein 1 (ZBP1) is a pattern recognition receptor that harbors two Zα domains that recognize...
NMR-based solution structure of the Caulobacter crescentus ProXp-ala trans-editing enzyme [0.03%]
产翘杆菌ProX脯氨酸-丙氨酰tRNA合成酶的溶液结构(基于核磁共振)
Antonia D Duran,Eric M Danhart,Xiao Ma et al.
Antonia D Duran et al.
ProXp-ala is a key component of the translational machinery in all three Domains of life. This enzyme helps to maintain the fidelity of proline codon translation through aminoacyl-tRNAPro proofreading. In the first step of tRNA aminoacylati...
Chemical shift assignments of the α-actinin C-terminal EF-hand domain bound to a cytosolic C0 domain of GluN1 (residues 841-865) from the NMDA receptor [0.03%]
α-actinin C端EF手柄结构域与谷氨酸N甲基D天冬氨酸受体GluN1(841-865)胞质C0结构域结合的化学位移分配
Aritra Bej,Johannes W Hell,James B Ames
Aritra Bej
N-methyl-D-aspartate receptors (NMDARs) consist of glycine-binding GluN1 and glutamate-binding GluN2 subunits that form tetrameric ion channels. NMDARs in the brain are important for controlling neuronal excitability to promote synaptic pla...
1H, 15N and 13C resonance assignments of eggcase silk protein 3 [0.03%]
鸡蛋壳丝蛋白3的氢-1(1H)、氮-15(15N)和碳-13(13C)共振指派
Shuixin Yu,Ruiqi Qin,Wensu Yuan et al.
Shuixin Yu et al.
Spider silk is a high-performance biomaterial known for its outstanding combination of strength and flexibility. Among the six distinct types of spider silk, eggcase silk stands out as it is exclusively produced from the tubuliform gland, p...
1H, 15N, and 13C resonance assignments of the N-terminal domain and ser-arg-rich intrinsically disordered region of the nucleocapsid protein of the SARS-CoV-2 [0.03%]
SARS-CoV-2核衣壳蛋白N端结构域和精- arg-丰富内在无序区域的1H,15N和13C共振指派
Peter R Bezerra,Ariana A Vasconcelos,Vitor S Almeida et al.
Peter R Bezerra et al.
The nucleocapsid (N) protein of SARS-CoV-2 is a multifunctional protein involved in nucleocapsid assembly and various regulatory functions. It is the most abundant protein during viral infection. Its functionality is closely related to its ...