Solution NMR backbone assignment of the N-terminal tandem Zα1-Zα2 domains of Z-DNA binding protein 1 [0.03%]
Z- DNA结合蛋白1的N端串联Zα1-Zα2结构域的溶液NMR主链归属分析
Lily G Beck,Jeffrey B Krall,Parker J Nichols et al.
Lily G Beck et al.
The detection of nucleic acids that are present in atypical conformations is a crucial trigger of the innate immune response. Human Z-DNA binding protein 1 (ZBP1) is a pattern recognition receptor that harbors two Zα domains that recognize...
NMR-based solution structure of the Caulobacter crescentus ProXp-ala trans-editing enzyme [0.03%]
产翘杆菌ProX脯氨酸-丙氨酰tRNA合成酶的溶液结构（基于核磁共振）
Antonia D Duran,Eric M Danhart,Xiao Ma et al.
Antonia D Duran et al.
ProXp-ala is a key component of the translational machinery in all three Domains of life. This enzyme helps to maintain the fidelity of proline codon translation through aminoacyl-tRNAPro proofreading. In the first step of tRNA aminoacylati...
Chemical shift assignments of the α-actinin C-terminal EF-hand domain bound to a cytosolic C0 domain of GluN1 (residues 841-865) from the NMDA receptor [0.03%]
α-actinin C端EF手柄结构域与谷氨酸N甲基D天冬氨酸受体GluN1（841-865）胞质C0结构域结合的化学位移分配
Aritra Bej,Johannes W Hell,James B Ames
Aritra Bej
N-methyl-D-aspartate receptors (NMDARs) consist of glycine-binding GluN1 and glutamate-binding GluN2 subunits that form tetrameric ion channels. NMDARs in the brain are important for controlling neuronal excitability to promote synaptic pla...
1H, 15N and 13C resonance assignments of eggcase silk protein 3 [0.03%]
鸡蛋壳丝蛋白3的氢-1（1H）、氮-15（15N）和碳-13（13C）共振指派
Shuixin Yu,Ruiqi Qin,Wensu Yuan et al.
Shuixin Yu et al.
Spider silk is a high-performance biomaterial known for its outstanding combination of strength and flexibility. Among the six distinct types of spider silk, eggcase silk stands out as it is exclusively produced from the tubuliform gland, p...
1H, 15N, and 13C resonance assignments of the N-terminal domain and ser-arg-rich intrinsically disordered region of the nucleocapsid protein of the SARS-CoV-2 [0.03%]
SARS-CoV-2核衣壳蛋白N端结构域和精- arg-丰富内在无序区域的1H，15N和13C共振指派
Peter R Bezerra,Ariana A Vasconcelos,Vitor S Almeida et al.
Peter R Bezerra et al.
The nucleocapsid (N) protein of SARS-CoV-2 is a multifunctional protein involved in nucleocapsid assembly and various regulatory functions. It is the most abundant protein during viral infection. Its functionality is closely related to its ...
1H, 13C and 15N resonance assignments of a shark variable new antigen receptor against hyaluronan synthase [0.03%]
鲨鱼可变新抗原受体的共振谱分配对抗透明质酸合成酶
Yuxin Liu,Hao Wang,Cookson K C Chiu et al.
Yuxin Liu et al.
Single domain antibody (sdAb) is only composed of a variable domain of the heavy-chain-only antibody, which is devoid of light chain and naturally occurring in camelids and cartilaginous fishes. Variable New Antigen Receptor (VNAR), a type ...
Manual and automatic assignment of two different Aβ40 amyloid fibril polymorphs using MAS solid-state NMR spectroscopy [0.03%]
利用固体状态NMR技术对两种不同的Aβ40淀粉样纤维多晶型进行手动和自动分配
Natalia Rodina,Riddhiman Sarkar,Dimitrios Tsakalos et al.
Natalia Rodina et al.
Amyloid fibrils from Alzheimer's amyloid-beta peptides (Aβ) are found to be polymorphic. So far, 14 Aβ40 fibril structures have been determined. The mechanism of why one particular protein sequence adopts so many different three-dimension...
1H, 13C and 15N assignment of self-complemented MrkA protein antigen from Klebsiella pneumoniae [0.03%]
克雷伯氏肺炎菌自我互补的MrkA蛋白抗原的氢-1，碳-13和氮-15归属化研究
Valentina Monaci,Gianmarco Gasperini,Lucia Banci et al.
Valentina Monaci et al.
Klebsiella pneumoniae (Kp) poses an escalating threat to public health, particularly given its association with nosocomial infections and its emergence as a leading cause of neonatal sepsis, particularly in low- and middle-income countries ...
Solid-state NMR assignment of α-synuclein polymorph prepared from helical intermediate [0.03%]
由螺旋中间体制备的α-突触核蛋白多态固体核磁共振 ASSIGNMENT
Sahil Ahlawat,Surabhi Mehra,Chandrakala M Gowda et al.
Sahil Ahlawat et al.
Synucleinopathies are neurodegenerative diseases characterized by the accumulation of α-synuclein protein aggregates in the neurons and glial cells. Both ex vivo and in vitro α-synuclein fibrils tend to show polymorphism. Polymorphism res...
Solid-state NMR backbone chemical shift assignments of α-synuclein amyloid fibrils at fast MAS regime [0.03%]
固态NMR研究α-突触核蛋白淀粉样纤维主链化学位移快速MAS制度
Zigmantas Toleikis,Piotr Paluch,Ewelina Kuc et al.
Zigmantas Toleikis et al.
The α-synuclein (α-syn) amyloid fibrils are involved in various neurogenerative diseases. Solid-state NMR (ssNMR) has been showed as a powerful tool to study α-syn aggregates. Here, we report the 1H, 13C and 15N back-bone chemical shifts...