Backbone resonance assignments of the C-terminal thioesterase domain of tyrocidine synthetase C [0.03%]
泰洛霉素合成酶C的羧基末端硫酯酶结构域的骨架共振分配
Mitsuhiro Takeda,Rino Saito,Sho Konno et al.
Mitsuhiro Takeda et al.
Natural macrocyclic peptides produced by microorganisms serve as valuable resources for therapeutic compounds, including antibiotics, anticancer agents, and immune suppressive agents. Nonribosomal peptide synthetases (NRPSs) are responsible...
1H, 13C, and 15N resonance assignments of the amyloidogenic peptide SEM2(49-107) by NMR spectroscopy [0.03%]
利用核磁共振技术对淀粉样蛋白肽SEM2（49-107）的氢、碳和氮原子进行共振标记
Anastasia A Troshkina,Vladimir V Klochkov,Aydar G Bikmullin et al.
Anastasia A Troshkina et al.
It has been shown that human seminal fluid is a major factor in enhancing HIV activity. The SEM2(49-107) peptide is a product of cleavage after ejaculation by internal prostheses of the semenogelin 2 protein, expressed in seminal vesicles. ...
1H, 15N and 13C backbone resonance assignment of the N-terminal region of Zika virus NS4B protein in detergent micelles [0.03%]
Zika病毒NS4B蛋白的N端区域在去垢剂胶束中的氢-15氮-13碳主链共振指派
Yan Li,Ying Ru Loh,Qingxin Li et al.
Yan Li et al.
Zika virus has raised global concerns due to its link to microcephaly and Guillain-Barré syndrome in adults. One of viral nonstructural proteins-NS4B, an integral membrane protein, plays crucial roles in viral replication by interacting wi...
Backbone 1H, 15N, and 13C resonance assignments of the FF1 domain from P190A RhoGAP in 5 and 8 M urea [0.03%]
P190A RhoGAP的FF1结构域在5和8M尿素中的Backbone 1H，15N和13C共振峰指认
Aarão Camilo-Ramos,Dmitry M Korzhnev,Ramon Pinheiro-Aguiar et al.
Aarão Camilo-Ramos et al.
The Rho GTPase (Ras homolog GTPases) system is a crucial signal transducer that regulates various cellular processes, including cell cycle and migration, genetic transcription, and apoptosis. In this study, we investigated the unfolded stat...
NMR assignment of the conserved bacterial DNA replication protein DnaA domain IV [0.03%]
细菌DNA复制蛋白DnaA保守区城IV的核磁共振波谱指认
Alexander Nguyen Abrams,Geoff Kelly,Julia Hubbard
Alexander Nguyen Abrams
Chromosomal replication is a ubiquitous and essential cellular process. In bacteria, the master replication initiator DnaA plays a key role in promoting an open complex at the origin (oriC) and recruiting helicase in a tightly regulated pro...
Imino chemical shift assignments of tRNAAsp, tRNAVal and tRNAPhe from Escherichia coli [0.03%]
来自大肠杆菌的tRNAAsp，tRNAVal和tRNAPhe的亚胺化学位移分配
Marcel-Joseph Yared,Carine Chagneau,Pierre Barraud
Marcel-Joseph Yared
Transfer RNAs (tRNAs) are an essential component of the protein synthesis machinery. In order to accomplish their cellular functions, tRNAs go through a highly controlled biogenesis process leading to the production of correctly folded tRNA...
Backbone assignments of the biotin carboxyl carrier protein domain of Propionyl CoA carboxylase of Leishmania major and its interaction with its cognate Biotin protein ligase [0.03%]
巴贝斯酸辅酶a羧化酶的赖氏裂体球菌生物素载体蛋白结构域及与同类生物素蛋白连接酶相互作用的主链共振 assignments
Sonika Bhatnagar,Debodyuti Sadhukhan,Monica Sundd
Sonika Bhatnagar
Propionyl CoA carboxylase (PCC) is a multimeric enzyme composed of two types of subunits, α and β arranged in α6β6 stoichiometry. The α-subunit consists of an N-terminal carboxylase domain, a carboxyl transferase domains, and a C-termi...
Yajing Duan,Wensu Yuan,Zhi Lin et al.
Yajing Duan et al.
Diverse extracellular sensor domains enable cells to regulate their behavior, physiological processes, and interspecies interactions in response to environmental stimuli. These sensing mechanisms facilitate the ultimate adaptation of organi...
1H, 15N and 13C resonance assignments of the S2A and H64A double mutant of human carbonic anhydrase II [0.03%]
人源碳酸酐酶II的S2A和H64A双突变体的氢-1（1H）、氮-15（15N）和碳-13（13C）共振指派
Neelam,Mandar Bopardikar,Himanshu Singh
Neelam
Protein-water interactions profoundly influence protein structure and dynamics. Consequently, the function of many biomacromolecules is directly related to the presence and exchange of water molecules. While structural water molecules can b...
Backbone assignment of CcdB_G100T toxin from E.coli in complex with the toxin binding C-terminal domain of its cognate antitoxin CcdA [0.03%]
Ecoli中CcdB_G100T毒素与其相应的解毒蛋白CcdA的结合端结构域复合物的主链共振峰.assignments
Bahnikana Nanda,Jayantika Bhowmick,Raghavan Varadarajan et al.
Bahnikana Nanda et al.
The CcdAB system expressed in the E.coli cells is a prototypical example of the bacterial toxin-antitoxin (TA) systems that ensure the survival of the bacterial population under adverse environmental conditions. The solution and crystal str...