Backbone assignment of the N-terminal domain of the A subunit of the Bacillus cereus GerI germinant receptor [0.03%]
伯克霍尔德菌毒力岛编码的金属醇脱氢酶VapD的作用底物及产物鉴定
Yulia Pustovalova,Yunfeng Li,Jeffrey C Hoch et al.
Yulia Pustovalova et al.
The nutrient germinant receptors (GRs) in spores of Bacillus species consist of a cluster of three proteins- designated A, B, and C subunits- that play a critical role in initiating the germination of dormant spores in response to specific ...
Hanna Aucharova,Rasmus Linser
Hanna Aucharova
Cyclic GMP-AMP synthase (cGAS) is a DNA-sensing enzyme that is a member of the nucleotidyltransferase (NTase) family and functions as a DNA sensor. The protein is comprised of a catalytic NTase core domain and an unstructured hypervariable ...
Backbone NMR resonance assignment of Sis1, a type B J-domain protein from Saccharomyces cerevisiae [0.03%]
酿酒酵母SIS1(J结构域蛋白B型)的骨干核磁共振共振谱鉴定
Glaucia M S Pinheiro,Gisele C Amorim,Carolina O Matos et al.
Glaucia M S Pinheiro et al.
J-domain proteins (JDPs) are essential cochaperones of heat shock protein 70 (Hsp70), as they bind and deliver misfolded polypeptides while also stimulating ATPase activity, thereby mediating the refolding process and assisting Hsp70 in mai...
Correction: 1H, 13C, and 15N resonance assignments of the amyloidogenic peptide SEM2(49-107) by NMR spectroscopy [0.03%]
关于肽SEMNMR光谱上的修正:1H、13C和15N共振指派(SEM2(49-107)是淀粉样原性肽)
Anastasia A Troshkina,Vladimir V Klochkov,Aydar G Bikmullin et al.
Anastasia A Troshkina et al.
Published Erratum
Biomolecular NMR assignments. 2024 Dec 27. DOI:10.1007/s12104-024-10214-1 2024
NMR resonance assignment of a ligand-binding domain of ephrin receptor A2 [0.03%]
EFNA2受体的配体结合结构域的核磁共振谱峰指认
Konstantin S Mineev,Santosh L Gande,Verena Linhard et al.
Konstantin S Mineev et al.
Ephrin receptors regulate intercellular communication and are thus involved in tumor development. Ephrin receptor A2 (EphA2), in particular, is overexpressed in a variety of cancers and is a proven target for anti-cancer drugs. The N-termin...
Backbone resonance assignments of the C-terminal thioesterase domain of tyrocidine synthetase C [0.03%]
泰洛霉素合成酶C的羧基末端硫酯酶结构域的骨架共振分配
Mitsuhiro Takeda,Rino Saito,Sho Konno et al.
Mitsuhiro Takeda et al.
Natural macrocyclic peptides produced by microorganisms serve as valuable resources for therapeutic compounds, including antibiotics, anticancer agents, and immune suppressive agents. Nonribosomal peptide synthetases (NRPSs) are responsible...
1H, 13C, and 15N resonance assignments of the amyloidogenic peptide SEM2(49-107) by NMR spectroscopy [0.03%]
利用核磁共振技术对淀粉样蛋白肽SEM2(49-107)的氢、碳和氮原子进行共振标记
Anastasia A Troshkina,Vladimir V Klochkov,Aydar G Bikmullin et al.
Anastasia A Troshkina et al.
It has been shown that human seminal fluid is a major factor in enhancing HIV activity. The SEM2(49-107) peptide is a product of cleavage after ejaculation by internal prostheses of the semenogelin 2 protein, expressed in seminal vesicles. ...
1H, 15N and 13C backbone resonance assignment of the N-terminal region of Zika virus NS4B protein in detergent micelles [0.03%]
Zika病毒NS4B蛋白的N端区域在去垢剂胶束中的氢-15氮-13碳主链共振指派
Yan Li,Ying Ru Loh,Qingxin Li et al.
Yan Li et al.
Zika virus has raised global concerns due to its link to microcephaly and Guillain-Barré syndrome in adults. One of viral nonstructural proteins-NS4B, an integral membrane protein, plays crucial roles in viral replication by interacting wi...
Backbone 1H, 15N, and 13C resonance assignments of the FF1 domain from P190A RhoGAP in 5 and 8 M urea [0.03%]
P190A RhoGAP的FF1结构域在5和8M尿素中的Backbone 1H,15N和13C共振峰指认
Aarão Camilo-Ramos,Dmitry M Korzhnev,Ramon Pinheiro-Aguiar et al.
Aarão Camilo-Ramos et al.
The Rho GTPase (Ras homolog GTPases) system is a crucial signal transducer that regulates various cellular processes, including cell cycle and migration, genetic transcription, and apoptosis. In this study, we investigated the unfolded stat...
NMR assignment of the conserved bacterial DNA replication protein DnaA domain IV [0.03%]
细菌DNA复制蛋白DnaA保守区城IV的核磁共振波谱指认
Alexander Nguyen Abrams,Geoff Kelly,Julia Hubbard
Alexander Nguyen Abrams
Chromosomal replication is a ubiquitous and essential cellular process. In bacteria, the master replication initiator DnaA plays a key role in promoting an open complex at the origin (oriC) and recruiting helicase in a tightly regulated pro...