Backbone NMR assignments of the essential oxidoreductase tryparedoxin from the human pathogenic parasite Trypanosoma cruzi [0.03%]
致病寄生虫Chagas病原体Trypanosoma cruzi的必需氧化还原酶Tryparedoxin的主体核磁共振谱鉴定
Eric Schwegler,Ute A Hellmich
Eric Schwegler
Over 7 million people worldwide are affected with Chagas disease, a lifelong debilitating and potentially fatal Neglected Tropical Disease caused by the single cell protozoan parasite Trypanosoma cruzi. To maintain viability and to reproduc...
Backbone assignment of a 28.5 kDa class A extended spectrum β-lactamase by high-field, carbon-detected solid-state NMR [0.03%]
高场碳探测固态NMR法测定扩展谱Broad Spectrum β-内酰胺类抗生素酶A组28.5 kDa的主链骨架原子化学位移指认
Christopher G Williams,Songlin Wang,Alexander F Thome et al.
Christopher G Williams et al.
13C and 15N backbone chemical shift assignments are reported for the 28.5 kDa protein Toho-1 β-lactamase, a Class A extended spectrum β-lactamase. A very high level of assignment completeness (97% of the backbone) is enabled by the combin...
NMR chemical shift assignment of UEV domain of ubiquitin-conjugating enzyme E2 variant 3 lactate dehydrogenase (UEVLD) [0.03%]
泛素连接酶E2变异体3乳酸脱氢酶（UEVLD）的UEV结构域的核磁共振化学位移指认
Jose G Vazquez,David A Nyenhuis,Marie-Paule Strub et al.
Jose G Vazquez et al.
UEV domains are catalytically dead variants of the E2 enzymes which play an intermediate role in ubiquitin signaling. UEV domain containing proteins, like the ESCRT-I factor Tsg101 often play critical roles in trafficking of ubiquitylated c...
Resonance assignment of the intrinsically disordered actin-binding region of Drebrin [0.03%]
邓地碱内在无序的肌动蛋白结合区的共振 assignments
Soma Varga,Julie Maibøll Kaasen,Zoltán Gáspári et al.
Soma Varga et al.
Drebrin (developmentally regulated brain protein) is a vital component of the Postsynaptic Density (PSD). It performs important biological roles as it interacts with the postsynaptic protein Homer and anchors the complete protein network to...
Backbone and sidechain 1H, 15N and 13C resonance assignments of a multidrug efflux membrane protein using solution and solid-state NMR [0.03%]
基于溶液和固态核磁共振技术对多药外排膜蛋白的主链及侧链（1H，15N和13C）进行定性分析
Benjamin D Harding,Ashley Hiett,Marco Tonelli et al.
Benjamin D Harding et al.
EmrE is a bacterial membrane-embedded multidrug transporter that functions as an asymmetric homodimer. EmrE is implicated in antibiotic resistance but is now known to confer either resistance or susceptibility depending on the identity of t...
Correction: Backbone resonance assignments of the CPEB3 [101-200] and CPEB3 [294-410] [0.03%]
纠正:CPEB3[101-200]和CPEB3[294-410]的主链共振赋值
Harunobu Saito,Yujin Lee,Motoharu Ueno et al.
Harunobu Saito et al.
Published Erratum
Biomolecular NMR assignments. 2025 May 9. DOI:10.1007/s12104-025-10237-2 2025
NMR 1H, 13C, and 15N resonance assignments of the oncogenic Q61R variant of human NRAS in the active, GTP-bound conformation [0.03%]
人源NRAS癌基因Q61R变异体在活性GTP结合构象下的氢质子、碳和氮的核磁共振波谱,assignments为“指派”或“分配”均可。
Alok K Sharma,Marco Tonelli,Marcin Dyba et al.
Alok K Sharma et al.
NRASQ61R is a frequent mutation in melanoma. Hydrolysis of GTP by NRASQ61R is reported to be much slower than other KRAS and NRAS mutants. Recent structural biology efforts for KRAS and NRAS proteins have been limited to X-ray crystallograp...
1H, 13C and 15N resonance assignments for the acetyltransferase domain of the kinetoplastid kinetochore protein KKT23 from Trypanosoma brucei [0.03%]
布鲁氏布氏锥虫染色体支架蛋白KKT23乙酰转移酶结构域的氢-1，碳-13和氮-15共振分配
Patryk Ludzia,Charlotte Nugent,Bungo Akiyoshi et al.
Patryk Ludzia et al.
KKT23 is a kinetoplastid-specific kinetochore protein that has a C-terminal GCN5-related histone acetyltransferase domain that acetylates the C-terminal tail of histone H2A. Here, we present the 1H, 13C and 15N resonance assignments for the...
1H, 13C, and 15N resonance assignment of the 5'SL-bound La domain of the human La-related protein 6 [0.03%]
人相关La蛋白6(LRP6)与5' SL结合的La结构域的氢-1，碳-13和氮-15共振分配
Blaine H Gordon,Robert Silvers
Blaine H Gordon
Human La-related protein 6 (HsLARP6) participates in the post-transcriptional regulation of type I collagen biosynthesis and is involved in the onset and progression of fibroproliferative disease. The RNA-binding protein HsLARP6 recognizes ...
13C and 15N resonance assignments of the DNA binding domain of interferon regulatory factor-3 [0.03%]
IFN调节因子-3DNA结合域的碳和氮共振峰鉴定
Nitin Dhaka,Sunirmala Sahoo,Biswajit Samal et al.
Nitin Dhaka et al.
The Interferon Regulatory Factor (IRF) family of transcription factors is well known for its anti-viral activity in vertebrates. The IRF family comprises nine members (IRF1-9) which have the ability to induce the Interferon beta (IFNβ) pro...