1H, 13C and 15N resonance assignments for the acetyltransferase domain of the kinetoplastid kinetochore protein KKT23 from Trypanosoma brucei [0.03%]
布鲁氏布氏锥虫染色体支架蛋白KKT23乙酰转移酶结构域的氢-1,碳-13和氮-15共振分配
Patryk Ludzia,Charlotte Nugent,Bungo Akiyoshi et al.
Patryk Ludzia et al.
KKT23 is a kinetoplastid-specific kinetochore protein that has a C-terminal GCN5-related histone acetyltransferase domain that acetylates the C-terminal tail of histone H2A. Here, we present the 1H, 13C and 15N resonance assignments for the...
1H, 13C, and 15N resonance assignment of the 5'SL-bound La domain of the human La-related protein 6 [0.03%]
人相关La蛋白6(LRP6)与5' SL结合的La结构域的氢-1,碳-13和氮-15共振分配
Blaine H Gordon,Robert Silvers
Blaine H Gordon
Human La-related protein 6 (HsLARP6) participates in the post-transcriptional regulation of type I collagen biosynthesis and is involved in the onset and progression of fibroproliferative disease. The RNA-binding protein HsLARP6 recognizes ...
13C and 15N resonance assignments of the DNA binding domain of interferon regulatory factor-3 [0.03%]
IFN调节因子-3DNA结合域的碳和氮共振峰鉴定
Nitin Dhaka,Sunirmala Sahoo,Biswajit Samal et al.
Nitin Dhaka et al.
The Interferon Regulatory Factor (IRF) family of transcription factors is well known for its anti-viral activity in vertebrates. The IRF family comprises nine members (IRF1-9) which have the ability to induce the Interferon beta (IFNβ) pro...
1H, 13C and 15N backbone resonance assignment of the catalytic domain of human PTPN22 [0.03%]
人类PTPN22催化结构域的氢-1,碳-13和氮-15主链共振指派
Bryan T Martin,Michael W Clarkson,Ping Wu et al.
Bryan T Martin et al.
Protein Tyrosine Phosphatase Non-receptor type 22 (PTPN22) is a tyrosine-phosphatase that plays a major role in inhibiting T-cell activation in immune cells. Recent studies have revealed that downregulation of PTPN22 triggers T-cell activat...
NMR chemical shift assignment of the IMLV methyl groups of a di-domain of the Tomaymycin non-ribosomal peptide synthetase [0.03%]
Tomaymycin非核糖体肽合成酶二结构域IMLV甲基位移的归属:NMR波谱研究
John P Kirkpatrick,Megha N Karanth,Teresa Carlomagno
John P Kirkpatrick
Non-ribosomal peptide synthetases (NRPSs) are macromolecular enzymatic complexes responsible for the biosynthesis of an array of microbial natural products, many of which have important applications for human health. The nature of the NRPS ...
Chemical shift assignments of the rib domain in a cell surface protein from Limosilactobacillus reuteri [0.03%]
乳酸菌赖瑟氏菌细胞表面蛋白的核磁共振实验研究
Yi Xue,Xue Kang
Yi Xue
The Rib domain, a conserved structural element found in Gram-positive bacterial cell surface proteins, plays a role in bacterial virulence and is a potential target for vaccine development. Despite the availability of high-resolution crysta...
1H, 13C and 15N chemical shift assignments of Rubella virus macro domain in the free and in the ADPr bound state [0.03%]
鲁伯列雅病毒巨域在自由及ADP核糖结合状态下的氢-1H、碳-13C和氮-15N的化学位移分配
Danai Moschidi,Nikolaos K Fourkiotis,Christos Sideras-Bisdekis et al.
Danai Moschidi et al.
Prokaryotes, eukaryotes, and certain viruses with positive single-stranded RNA genomes are among the forms of life that have been found to possess macro domains (MDs). There are claims that viral MDs inhibit the immune response mediated by ...
1H, 13C and 15N resonance assignments of the third intracellular loop of the muscarinic acetylcholine receptor M1 [0.03%]
Muscarinic乙酰胆碱受体M1的第三个细胞内环的氢-1(1H),碳-13(13C)和氮-15(15N)共振指派
Jiannan Wang,Xiaogang Niu,Changwen Jin et al.
Jiannan Wang et al.
G protein-coupled receptors (GPCRs) are highly dynamic seven-transmembrane (7TM) proteins that respond to various extracellular stimuli and elicit diverse intracellular signaling cascades. The third intracellular loops (ICL3s) of the GPCRs ...
NMR characterisation of the antibiotic resistance-mediating 32mer RNA from the 23S ribosomal RNA [0.03%]
抗生素抗性介导的32核苷酸RNA的核磁共振表征:来自23S核糖体RNA
Christina Muhs,Lena Kemper,Christian Richter et al.
Christina Muhs et al.
The increasing prevalence of antibiotic resistance represents a significant public health concern, underscoring the urgent need for the development of novel therapeutic strategies. The antibiotic effects of macrolides, the second most widel...
Backbone resonance assignments of the CPEB3 [101-200] and CPEB3 [294-410] [0.03%]
CPEB3 [101-200] 和 CPEB3 [294-410] 的后背共振分配
Harunobu Saito,Yujin Lee,Tomoharu Ueno et al.
Harunobu Saito et al.
Cytoplasmic polyadenylation element-binding protein 3 (CPEB3) is an RNA-binding protein that plays a pivotal role in the formation of long-term memory. The N-terminal region (residues 1-459) of CPEB3 is a highly aggregative intrinsically di...