1H, 13C, and 15N backbone resonance assignments of full-length and a SIM-SEP-containing fragment (101-266) of p47, a p97 adaptor protein [0.03%]
全长和含SIM-SEP片段（101-266）的p47的氢-13碳-15氮主链共振分配（p97适配蛋白）
Rajivan Raseekan,Megan K Black,Rui Huang
Rajivan Raseekan
p47/NSFL1C is a key adaptor protein of p97/VCP, a AAA+ ATPase that is involved in a diverse array of cellular functions. p47 directs p97 activity towards membrane remodelling and contributes to the regulation of cellular pathways such as NF...
Resonance assignments of the human receptor interacting protein kinase 1 (RIPK1) in its fibrillar conformation [0.03%]
人交互作用蛋白激酶1（RIPK1）原纤维构象的共振赋值
Paula Polonio,Miguel Mompeán
Paula Polonio
Receptor-interacting protein kinase 1 (RIPK1) is a key regulator of necroptotic signalling that forms functional amyloid fibrils through its RIP Homotypic Interaction Motif (RHIM). Here, we report the solid-state NMR chemical shift assignme...
1H, 13C and 15N backbone resonance assignment of the RNA binding motif 39 (RBM39) tandem RNA recognition motifs (RRM1-2) [0.03%]
RBM39 蛋白 RRMs 1-2 域的氮氢原子核磁共振谱的完全分配
Florian Malard,Léa Bouton,Sébastien Campagne
Florian Malard
The N-terminal tandem RNA Recognition Motifs (RRM1-2) of the splicing factor RNA Binding Motif 39 (RBM39) from Homo sapiens was expressed in E. coli with 13C and 15N labeling. A nearly complete assignment of backbone 1H, 15N, and 13C resona...
Abigail Page,Wyatt Hendricks,Marielle A Wälti
Abigail Page
The human chaperonin system, Hsp60/Hsp10, is essential for maintaining protein homeostasis and is found mainly in mitochondria. Hsp60 forms a bowl-shaped structure that provides an enclosed environment for protein folding, while its co-chap...
Resonance assignments of asymmetric tetrameric platelet factor 4 (PF4) [0.03%]
不对称四聚体血小板因子4(PF4)的共振赋值
Qiulin Ma,Jinfeng Huang,Stephen Boulton et al.
Qiulin Ma et al.
Platelet Factor 4 (PF4), also known as CXCL4, is a CXC chemokine crucial for hemostasis, inflammation, and immune responses. Under physiological conditions PF4 assembles into asymmetric tetramers (31.2 kDa) that are dimers of dimers with hi...
1H, 15N and 13C backbone resonance assignments of flap endonuclease from Plasmodium falciparum [0.03%]
疟原虫 flapendonuclease 的氢-氮-碳 氨基酸残基共振分配
Rodolpho do Aido-Machado,Nicola J Baxter,Michelle L Rowe et al.
Rodolpho do Aido-Machado et al.
Flap endonuclease (FEN) enzymes are a group of metallonucleases that have essential roles in DNA repair and the maintenance of genomic resilience. They catalyse hydrolytic cleavage of a phosphodiester bond to remove 5'-flaps present on doub...
1H, 13C and 15N chemical shift assignment for stem-loop 5a from the 5'UTR of HCoV-229E [0.03%]
人冠状病毒HCoV-229E的5'-UTR茎环5a的氢-1（1H），碳-13（13C）和氮-15（15N）化学位移分配
Nina M Krause,Anna Wacker,Christian Richter et al.
Nina M Krause et al.
Due to the emergence of the SARS-CoV-2 virus, research on coronaviruses has been massively accelerated. In addition to SARS-CoV-2, there are other human coronaviruses, including HCoV-229E. In all coronaviruses, secondary structure predictio...
1H, 13C, 15N backbone chemical shift assignment of P18ink4c from Danio rerio (zebrafish) using solution-state NMR spectroscopy [0.03%]
利用溶液核磁共振技术测定斑马鱼P18ink4c的1H，13C和15N背骨化学位移值
Aakriti Sethi,Pierre de Cordovez,Biswaranjan Mohanty et al.
Aakriti Sethi et al.
The INK4 family of proteins restricts uncontrolled cell cycle progression by inhibiting cyclin-dependent kinases 4 and 6. The family consists of small, monomeric and mainly alpha-helical proteins that are conserved across all vertebrate spe...
Backbone NMR assignments of the essential oxidoreductase tryparedoxin from the human pathogenic parasite Trypanosoma cruzi [0.03%]
致病寄生虫Chagas病原体Trypanosoma cruzi的必需氧化还原酶Tryparedoxin的主体核磁共振谱鉴定
Eric Schwegler,Ute A Hellmich
Eric Schwegler
Over 7 million people worldwide are affected with Chagas disease, a lifelong debilitating and potentially fatal Neglected Tropical Disease caused by the single cell protozoan parasite Trypanosoma cruzi. To maintain viability and to reproduc...
Backbone assignment of a 28.5 kDa class A extended spectrum β-lactamase by high-field, carbon-detected solid-state NMR [0.03%]
高场碳探测固态NMR法测定扩展谱Broad Spectrum β-内酰胺类抗生素酶A组28.5 kDa的主链骨架原子化学位移指认
Christopher G Williams,Songlin Wang,Alexander F Thome et al.
Christopher G Williams et al.
13C and 15N backbone chemical shift assignments are reported for the 28.5 kDa protein Toho-1 β-lactamase, a Class A extended spectrum β-lactamase. A very high level of assignment completeness (97% of the backbone) is enabled by the combin...