Nuclear hormone receptors control fundamental processes of human fetal neurodevelopment: Basis for endocrine disruption assessment [0.03%]
核激素受体控制人类胎儿神经发育的基本过程：内分泌干扰评估的基础
Katharina Koch,Kevin Schlüppmann,Saskia Hüsken et al.
Katharina Koch et al.
Despite growing awareness of endocrine disrupting chemicals (EDCs), knowledge gaps remain regarding their effects on human brain development. EDC risk assessment focuses primarily on EATS modalities (estrogens, androgens, thyroid hormones, ...
Evaluating PFAS-Induced modulation of peripheral blood mononuclear cells (PBMCs) immune response to SARS-CoV-2 spike in COVID-19 Vaccinees [0.03%]
评估PFAS引起的外周血单个核细胞(PBMCs)对COVID-19疫苗接种者SARS-CoV-2刺突的免疫反应调节
Humblenoble Stembridge Ayuk,Arkadiusz Pierzchalski,Tamara Tal et al.
Humblenoble Stembridge Ayuk et al.
The persistent nature of the environmental contaminants per- and polyfluoroalkyl substances (PFAS) has recently received considerable attention, particularly because of their adverse effects on immune system functionality in the context of ...
Serum biomonitoring of per- and polyfluoroalkyl substances (PFASs) in the adult population of Switzerland: Results from the pilot phase of the Swiss health study [0.03%]
瑞士成人人群中全氟和多氟烷基物质(PFAS)的血清生物监测：瑞士健康研究试点阶段的结果
Alexandra Jaus,Céline Fragnière Rime,Julien Riou et al.
Alexandra Jaus et al.
Monitoring human exposure to per- and polyfluoroalkyl substances (PFASs) is of significant public health relevance, given the documented associations between PFAS exposure and a range of adverse health outcomes. This study aimed to provide ...
Epidemiological characteristics of antibiotic resistance genes in various bacteria worldwide [0.03%]
全球各种细菌中抗生素抗性基因的流行病学特征
Jingpeng Liu,Yixin Ma,Yuechen Sun et al.
Jingpeng Liu et al.
Objectives: This study aims to investigate the epidemiological characteristics of various bacteria carrying ARGs on a global scale over extended time periods. ...
Phase-dependent hepatotoxicity of Aluminum oxide nanoparticles mediated through the intestinal microbiota [0.03%]
铝氧化物纳米颗粒通过肠道微生物介导的随阶段变化的肝毒性效应
Mingshu Li,Fuchang Deng,Li Dong et al.
Mingshu Li et al.
Aluminum oxide (Al2O3) nanoparticles (NPs) are extensively utilized in the food industry for applications such as food packaging, antimicrobial coatings, food processing equipment, and additives. Despite their widespread use, the mechanisms...
Combination of suspect and nontarget screening with exposure assessment for per- and polyfluoroalkyl substance prioritization in Chinese municipal wastewater [0.03%]
中国市政污水中全氟和多氟烷基物质的嫌疑物和非目标筛查与暴露评估相结合的优先排序方法
Hongxin Mu,Ling Chen,Rong Zhou et al.
Hongxin Mu et al.
Municipal wastewater treatment plants (WWTPs) are significant sources of per- and polyfluoroalkyl substances (PFASs) in aquatic environments, making their identification and priority rank crucial for risk control. Wastewater samples were co...
Advancing non-target analysis of emerging environmental contaminants with machine learning: Current status and future implications [0.03%]
机器学习在新兴环境污染物的非目标分析中的应用：现状与未来展望
Alexa Canchola,Lillian N Tran,Wonsik Woo et al.
Alexa Canchola et al.
Emerging environmental contaminants (EECs) such as pharmaceuticals, pesticides, and industrial chemicals pose significant challenges for detection and identification due to their structural diversity and lack of analytical standards. Tradit...
Characteristics and influencing factors of microplastics entering human blood through intravenous injection [0.03%]
静脉注射进入人体血液的微塑料特征及其影响因素
Bowen Li,Min Li,Dongwei Du et al.
Bowen Li et al.
The presence of microplastics in the human body and their potential health risks have drawn widespread attention in recent years. Microplastics have been detected in human blood, though their pathways of entry remain unclear. This study emp...
Long term exposure to multiple environmental stressors induces mitochondrial dynamics imbalance in testis: Insights from metabolomics and transcriptomics [0.03%]
长期暴露于多种环境压力因素会导致睾丸中的线粒体动态失衡：来自代谢组学和转录组学的见解
Shiqin Jiang,Tianli Nong,Ting Yu et al.
Shiqin Jiang et al.
Long-term exposure to adverse environment stressors (e.g. noise pollution, temperature, and crowding) impaired human health. However, research on the toxic effects of adverse environmental stressors on the male reproductive system is limite...
Examining the social distributions in neighbourhood black carbon and ultrafine particles in Montreal and Toronto, Canada [0.03%]
检查加拿大蒙特利尔和多伦多邻里黑碳和超细颗粒物的社会分布情况
Emmanuelle Batisse,Marshall Lloyd,Alicia Cavanaugh et al.
Emmanuelle Batisse et al.
Background: Socioeconomic inequities in outdoor ultrafine particles (UFP) and black carbon (BC) are understudied in Canada, where metropoles like Montreal and Toronto feature distinct sociodemographic diversity and urban ...