CircRNA0052011 modulates DNA damage and repair via FEN1 ubiquitination to mitigate polystyrene nanoplastics-induced genotoxicity in the lung [0.03%]
Circular RNA0052011通过FEN1泛素化调节DNA损伤和修复以缓解肺部聚苯乙烯纳米塑料引起的遗传毒性
Meiqi Lan,Chenghui Zhong,Xiaole Xu et al.
Meiqi Lan et al.
Polystyrene nanoplastics (PS-NPs) are one type of environmental pollutants that can penetrate biological barriers and accumulate within cells due to their small particle size. This characteristic raises concerns about their potential respir...
Mapping the impact of prolonged microplastics exposure on enteric viral infections using human intestinal organoids [0.03%]
利用人体肠类器官绘制长期暴露于微塑料对肠道病毒感染的影响地图
Jiangrong Zhou,Yilan Zhao,Xincheng Li et al.
Jiangrong Zhou et al.
Micro- and nanoplastic particles (MNPs) are pervasive environmental pollutants increasingly detected in the human body, yet the health consequences of chronic exposure remain poorly defined. Human intestinal organoids (HIO) have emerged as ...
Dynamic fate of polystyrene microplastics in terrestrial snails through dietary exposure: accumulation, excretion, and molecular impacts [0.03%]
通过饮食暴露于陆地螺体内的聚苯乙烯微塑料的动态命运：积累、排泄和分子影响
Wenwen Xie,Cheng Peng,Jun Chen et al.
Wenwen Xie et al.
Microplastic (MPs) pollution poses significant environmental and health risks due to its widespread presence and persistence in ecosystems. Despite growing concerns, there is a lack of comprehensive studies investigating the mechanistic cas...
Unveiling global population exposure to biomass burning: index development and its drivers over two decades [0.03%]
全球生物燃料燃烧人口暴露评估：二十年变化及驱动因素分析
Li Su,Shuai Yin,Husi Letu et al.
Li Su et al.
Biomass burning is an important source of global greenhouse gases, trace gases and aerosols. With global climate warming, biomass burning poses escalating risks to human health and ecosystems. However, rapidly and comprehensively assessing ...
SkinCast: an AI-driven mechanistically interpretable model for predicting skin sensitization of environmentally released consumer product ingredients [0.03%]
皮肤过敏预测模型SkinCast：一种具有机械解释性的AI驱动模型用于预测环境释放的消费品成分引起的皮肤过敏反应
Sujin Lee,Haena Kim,Sunmi Kim et al.
Sujin Lee et al.
Consumer product ingredients released into the environment may cause secondary human exposure and potential adverse outcomes (AOs) such as skin sensitization, a complex immunological process defined by four key events (KEs) within the AO pa...
Towards a unified framework for biodiversity action in the Triple Planetary Crisis [0.03%]
迈向应对三位一体地球危机的生物多样性行动统一框架
Jiarui Zhou,Jacopo Cricchio,Francisco Sylvester et al.
Jiarui Zhou et al.
Climate change, pollution, and biodiversity loss constitute the Triple Planetary Crisis, eroding the ecological foundations of economies, public health, and human wellbeing. Yet among these threats, biodiversity remains the least understood...
Maternal paraben exposure during early pregnancy is associated with altered cord blood DNA methylation: The PREDO cohort [0.03%]
孕期早期接触对羟基苯甲酸酯与脐带血DNA甲基化改变有关：PREDO队列研究
Marjaana Mäkinen,Johanna Tuhkanen,Marius Lahti-Pulkkinen et al.
Marjaana Mäkinen et al.
Background: Prenatal exposure to parabens, which are environmental endocrine disrupting chemicals and widely used preservatives in cosmetics, may alter DNA methylation (DNAm) in cord blood. Study design In 328 mother-chil...
Wildfire smoke-related PM2.5 concentration measurements, perceived indoor air quality, and health symptoms among Southern California residents during the 2025 Los Angeles wildfires: A latent class mediation approach [0.03%]
2025年洛杉矶野火期间南加州居民的PM2.5浓度测量、感知室内空气质量及健康症状：潜在类别中介法 APPROVED
Ryan Lee,Jennifer B Unger,Stefan Schneider et al.
Ryan Lee et al.
Introduction: Numerous studies have linked wildfire exposure to adverse physical and mental health outcomes and symptoms. However, few studies incorporate both outdoor wildfire smoke-related PM2.5 concentration and indoor...
BeefPOP: a physiologically based toxicokinetic model describing the fate of polychlorinated biphenyls in growing beef cattle [0.03%]
BeefPOP：生长肉牛多氯联苯毒代动力学的生理基础模型
Audrey Tiercin,John Albechaalany,Charlotte Driesen et al.
Audrey Tiercin et al.
Polychlorinated biphenyls (PCBs) are persistent organic pollutants that bioaccumulate in livestock and threaten food safety. Understanding PCB kinetics in farm animals is essential for effective risk management. This study introduces BeefPO...
Ambient air pollution during pregnancy and offspring cerebral palsy [0.03%]
孕期暴露于 ambient 空气污染和子代脑性麻痹风险的关系研究
Haoran Zhuo,Beate Ritz,Jason G Su et al.
Haoran Zhuo et al.
Background: Cerebral palsy (CP) is a permanent neuromotor disorder with childhood onset, and the etiology for most cases remains unexplained. Methods: ...