Chitosan biomaterial enhances the effect of OECs on the inhibition of sciatic nerve injury-induced neuropathic pain [0.03%]
壳聚糖生物材料增强OECs对坐骨神经损伤诱导的神经痛的抑制作用
Jia-Ling Hu,Hong-Liang Luo,Ji-Peng Liu et al.
Jia-Ling Hu et al.
Neuropathic pain is a common symptom experienced by most clinical diseases at different levels, and its treatment has always been a clinical difficulty. Therefore, it is particularly important to explore new and effective treatment methods....
Maternal diabetes decreases the expression of α2-adrenergic and M2 muscarinic receptors in the visual cortex of male rat neonates [0.03%]
母糖尿病降低雄性大鼠新生儿视觉皮层α2肾上腺素能和M2胆碱能受体的表达
Javad Bagheri,Somaye Fallahnezhad,Nasim Alipour et al.
Javad Bagheri et al.
Aims: This study investigates the impact of maternal diabetes on the expression of α2-adrenergic and M2 muscarinic receptors in the primary visual cortex of male offspring born to diabetic rats. ...
Isoflurane-induced reduction in neurogenesis derived from the tertiary dentate matrix [0.03%]
异氟烷通过作用于齿状回特三级基质而减少神经发生
Xin-Li Xiao,Da-Meng Pan,Zhe-Qian Zhang et al.
Xin-Li Xiao et al.
Anesthetics-induced disruption of dentate neurogenesis in the young brain is strongly suggested to contribute to delayed neurocognitive deficit. In postnatal rodents, the neurogenesis of the dentate gyrus (DG) is sequentially derived from t...
Changes in hypothalamic mu-opioid receptor expression following acute olanzapine treatment in female rats: Implications for feeding behavior [0.03%]
急性奥氮平处理对雌性大鼠下丘脑μ-阿片受体表达的影响及其对摄食行为的意义
Maiken Krogsbaek,Nick Yao Larsen,Anne M Landau et al.
Maiken Krogsbaek et al.
Advances have been made in recent years in using opioid receptor antagonists as an adjunct therapy to psychotropic medication to reduce debilitating weight gain and metabolic adverse effects associated with in particular second generation a...
Sex-dependent endozepinergic regulation of ventromedial hypothalamic nucleus glucose counter-regulatory neuron aromatase protein expression in the adult rat [0.03%]
成人大鼠下丘脑腹内侧核糖原反调节神经元芳香化酶蛋白的性别依赖性内源苯二氮草类调节
A S M Hasan Mahmood,Sagor C Roy,Jérôme Leprince et al.
A S M Hasan Mahmood et al.
The hypothalamic brain cell types that produce estradiol from testosterone remain unclear. Aromatase inhibition affects ventromedial hypothalamic nucleus (VMN) glucose-stimulatory nitric oxide (NO) and glucose-inhibitory γ-aminobutyric aci...
Hyperbaric oxygen therapy and coenzyme Q10 synergistically attenuates damage progression in spinal cord injury in a rat model [0.03%]
高压氧和辅酶Q10联合治疗脊髓损伤大鼠的协同效应研究
Alireza Ghaemi,Mohammad Ghiasvand,Melody Omraninava et al.
Alireza Ghaemi et al.
Background: Identifying effective spinal cord injury (SCI) treatments remains a major challenge, and current approaches are still unable to effectively improve its. Currently, we investigated the combined effects of hyper...
The many "Neurofaces" of Prohibitins 1 and 2: Crucial for the healthy brain, dysregulated in numerous brain disorders [0.03%]
禁止蛋白1和2的多种“神经面孔”：健康大脑不可或缺，多种脑部疾病的调控目标
Hans-Gert Bernstein,Karl-Heinz Smalla,Gerburg Keilhoff et al.
Hans-Gert Bernstein et al.
Prohibitin 1 (PHB1) and prohibitin 2 (PHB2) are proteins that are nearly ubiquitously expressed. They are localized in mitochondria, cytosol and cell nuclei. In the healthy CNS, they occur in neurons and non-neuronal cells (oligodendrocytes...
Neuroprotective anticonvulsant and anxiolytic effects of octreotide in wistar rats [0.03%]
奥曲肽的神经保护性抗惊厥和抗焦虑效应：大鼠模型研究
Tahereh Karimi Shayan,Arash Abdolmaleki,Asadollah Asadi et al.
Tahereh Karimi Shayan et al.
Somatostatin interneurons exhibited anti-epileptic activity. As a result, somatostatin agonists appear to be a promising target for antiepileptic drug development (AEDs). In this regard, we investigated the effects of octreotide, a somatost...
G protein-coupled estrogen receptor 1 deficiency impairs adult hippocampal neurogenesis in mice with schizophrenia [0.03%]
G蛋白偶联雌激素受体1缺乏损害了小鼠精神分裂症的成人海马神经发生
Chun Zhang,Jian-Guo Niu,Xue-Rui Kong et al.
Chun Zhang et al.
Objective: This study aimed to confirm that G protein-coupled estrogen receptor 1 (GPER1) deficiency affects cognitive function by reducing hippocampal neurogenesis via the PKA/ERK/IGF-I signaling pathway in mice with sch...
The antipsychotic olanzapine reduces memory deficits and neuronal abnormalities in a male rat model of Autism [0.03%]
奥氮平降低自闭症大鼠模型的空间记忆缺损和神经元异常
Luis Ángel Lima-Castañeda,María Elena Bringas,Leonardo Aguilar-Hernandez et al.
Luis Ángel Lima-Castañeda et al.
The prevalence of autism spectrum disorder (ASD), a neurodevelopmental condition that impacts social interaction and sensory processing, is rising. Valproic acid (VPA) exposure during pregnancy causes autistic-like traits in offspring. Olan...