Celecoxib attenuates neuroinflammation, reactive astrogliosis and promotes neuroprotection in young rats with experimental hydrocephalus [0.03%]
塞来昔布减轻实验性脑积水幼年大鼠的神经炎症和反应性星形胶质细胞增生并促进神经保护作用
Maurício Dutra,Stephanya Covas da Silva,Pâmella da Silva Beggiora Marques et al.
Maurício Dutra et al.
Hydrocephalus is a neurological condition with altered cerebrospinal fluid flow (CSF). The treatment is surgical and the most commonly used procedure is ventricle-peritoneal shunt. However, not all patients can undergo immediate surgery or ...
Activation patterns of dopaminergic cell populations reflect different learning scenarios in a cichlid fish, Pseudotropheus zebra [0.03%]
斑马贻贝壳斑鱼在不同学习情境下多巴胺神经元簇的激活模式研究
Calvo Roberta,Schluessel Vera,Hofmann Hans A et al.
Calvo Roberta et al.
Dopamine is present in all vertebrates and the functional roles of the subsystems are assumed to be similar. Whereas the effect of dopaminergic modulation is well investigated in different target systems, less is known about the factors tha...
Neurobiological and pathophysiological concepts of Christfried Jakob (1866-1956) on language and aphasia: An English translation of two communications [1910,1932] and a modern perspective [0.03%]
克里斯蒂安·雅科布(1866-1956)关于语言和失语症的神经生物学及病理生理学概念:[1910,1932]年两项交流内容英文翻译及现代视角
Maria E Vasilopoulou,Lazaros C Triarhou
Maria E Vasilopoulou
The aim of the present article is to preserve, in English translation, two historical communications on aphasia and the pathophysiology of language by the neurobiologist Christfried Jakob (1866-1956) of Buenos Aires, and to place them in a ...
The potential effect of salvianolic acid B against rat ischemic brain injury in combination with mesenchymal stem cells [0.03%]
丹参素B联合间充质干细胞治疗大鼠脑缺血的协同作用研究
Minli Yan,Zheming Li,Shijie Dai et al.
Minli Yan et al.
Background: Mesenchymal stem cells (MSCs) and Salvianolic acid B (SAB) are known to exert potent anti-inflammatory and anti-oxidative properties. But the effect of SAB and MSCs combination treatment on the cerebral ischem...
Gelatin/polyethylene glycol-loaded magnesium hydroxide nanocomposite to attenuate acetylcholinesterase, neurotoxicity, and activation of GPR55 protein in rat models of Alzheimer's disease [0.03%]
用于阿尔茨海默病大鼠模型的明胶/聚乙二醇负载氢氧化镁纳米复合材料以减弱乙酰胆碱酯酶、神经毒性以及活化GPR55蛋白
Manickam Rajkumar,Sundarraj Navaneethakrishnan,Sundarapandian Muthukumar et al.
Manickam Rajkumar et al.
Alzheimer's disease (AD) is a neurodegenerative disease marked by mitochondrial dysfunction, amyloid-β (Aβ) aggregation, and neuronal cell loss. G-protein-coupled receptor 55 (GPR55) has been used as a promising target for insulin recepto...
Cladribine induces apoptosis, neuroinflammation, mitochondrial oxidative stress, tau phosphorylation and Aβ (1-42) pathway in the hippocampus: An in vivo approach [0.03%]
克拉利丁诱导小鼠海马细胞凋亡、神经炎症、线粒体氧化应激、tau蛋白磷酸化和Aβ (1-42)通路:体内研究方法
Khadga Raj Aran,G D Gupta,Shamsher Singh
Khadga Raj Aran
Cladribine is a purine nucleoside found to enhance toxic amyloid protein and cause memory impairment. Patients following chemotherapy treatment commonly suffer from cognitive deficits more prevalent in the elderly than adults. A previous re...
GABA-immunoreactive neurons in the Central Nervous System of the viviparous teleost Poecilia sphenops [0.03%]
活胎鳉鱼Poecilia sphenops中枢神经系统中GABA阳性神经元的研究
Achyutham Hotha,C B Ganesh
Achyutham Hotha
Gamma-aminobutyric acid (GABA) functions as the primary inhibitory neurotransmitter within the central nervous system (CNS) of vertebrates. In this study, we examined the distribution pattern of GABA-immunoreactive (GABA-ir) cells and fibre...
Exploring the effects of embryonic and neonatal exposure to lipopolysaccharides on oligodendrocyte differentiation in the rat hippocampus and the protective effect of alpha-glycosyl isoquercitrin [0.03%]
探讨胚胎和新生儿期暴露内毒素对大鼠海马区少突胶质细胞分化的影响及异鼠李糖型异檞皮苷的保护作用
Hiromu Okano,Ryota Ojiro,Xinyu Zou et al.
Hiromu Okano et al.
This study compared the effects of embryonic and neonatal lipopolysaccharides (LPS) exposure (E-LPS and N-LPS) on oligodendrocyte (OL) differentiation in the hippocampus of male rats and explored the protective effect of the antioxidant alp...
Dendritic reorganization in the hippocampus, anterior temporal lobe, and frontal neocortex of lithium-pilocarpine induced Status Epilepticus (SE) [0.03%]
锂-匹罗卡品诱导的局灶性脑炎癫痫持续状态(Status Epilepticus,SE)后海马、颞叶和前额叶皮层树突形态的重塑
Vivek Dubey,Avishek Roy,Aparna Banerjee Dixit et al.
Vivek Dubey et al.
Status Epilepticus (SE) is a distributed network disorder, which involves the hippocampus and extra-hippocampal structures. Epileptogenesis in SE is tightly associated with neurogenesis, plastic changes and neural network reorganization fac...
Aerobic exercise training reduces deep-frying oil-induced apoptosis of hippocampal tissue by reducing oxidative stress in male rats [0.03%]
有氧运动训练通过降低氧化应激减少男性大鼠脑组织煎炸油诱导的细胞凋亡
Sina Nikbin,Gita Fardad,Sara Yazdi et al.
Sina Nikbin et al.
Deep-frying oil (DFO) contains high amounts of free radicals, and consuming foods prepared with this method causes damage to nervous tissue due to oxidative stress (OS). Since moderate-intensity aerobic exercise training (AT) reduces OS, th...