Curcumin alleviates Alzheimer's disease by inhibiting inflammatory response, oxidative stress and activating the AMPK pathway [0.03%]
姜黄素通过抑制炎症反应和氧化应激及激活AMPK通路缓解阿尔茨海默病
Sen Shao,Xiaojun Ye,Wenwen Su et al.
Sen Shao et al.
Background: Alzheimer's disease (AD) is a common degenerative brain disorder with limited therapeutic options. Curcumin (Cur) exhibits neuroprotective function in many diseases. We aimed to explore the role and mechanism ...
Spatiotemporal expression patterns of ZBP1 in the brain of mouse experimental stroke model [0.03%]
小鼠脑缺血模型中ZBP1的时空表达模式
Tohru Mutoh,Hiroshi Kikuchi,Tatsuya Jitsuishi et al.
Tohru Mutoh et al.
Z-DNA binding protein 1 (ZBP1) is a cytosolic nucleic acid sensor, functioning as a critical mediator of inflammation and cell death pathways. Since neuroinflammation could occur in response to damage-associated molecular patterns (DAMPs), ...
Synaptamide modulates glial and neurotransmitter activity in the spinal cord during neuropathic pain [0.03%]
辛普塔米德调节神经病理性疼痛期间脊髓中的星形胶质细胞和神经递质活性
Anna Starinets,Arina Ponomarenko,Anna Tyrtyshnaia et al.
Anna Starinets et al.
N-docosahexaenoylethanolamine, or synaptamide, is an endogenous metabolite of docosahexaenoic acid that is known for synaptogenic and neurogenic effects. In our previous studies we have shown that synaptamide attenuates neuropathic pain, fa...
Effect of royal jelly on acrylamide-induced neurotoxicity in rats [0.03%]
royal jelly对丙烯酰胺致大鼠神经毒性的影响
Doaa S Ibrahim,Eman M S Shahen
Doaa S Ibrahim
Royal Jelly (RJ) is a natural product made by nurse bees known for its multiple therapeutic properties. The research aims to discover the ability of RJ to improve the hematological alterations and neurotoxicity caused by acrylamide (AA). Th...
Suanzaoren decoction improves depressive-like behaviors by regulating the microbiota-gut-brain axis via inhibiting TLR4/NFκB/NLRP3 inflammation signal pathway [0.03%]
酸枣仁汤通过抑制TLR4/NFκB/NLRP3炎症信号途径调节微生态-肠-脑轴以改善抑郁样行为
Yiyang Du,Bosai He,Bo Wu et al.
Yiyang Du et al.
Depression is a common but serious sickness which causes a considerable burden on individuals and society. Recently, it has been well established that the occurrence of depression was related to the microbiota-gut-brain axis. The toll-like ...
An investigation of the endoplasmic reticulum stress in obesity exposure in the prenatal period [0.03%]
孕期肥胖暴露的内质网应激研究
Kıymet Kübra Tüfekci,Musa Tatar,Funda Terzi et al.
Kıymet Kübra Tüfekci et al.
Objectives: Exposure to maternal obesity has been shown to make offspring more prone to cognitive and metabolic disorders later in life. Although the underlying mechanisms are unclear, the role of endoplasmic reticulum (E...
Immunoreactivity of glutamine synthetase in satellite glia around various subpopulations of lumbar dorsal root ganglia neurons in adult rats treated with monosodium glutamate [0.03%]
单钠谷氨酸处理成年大鼠腰背根神经节各类神经元卫星胶质细胞的谷氨酰胺合成酶免疫反应性分布
Aleksandra Krawczyk,Sylwia Mozel,Karol Rycerz et al.
Aleksandra Krawczyk et al.
Satellite glial cells (SGCs), involved inter alia in glutamate (Glu) metabolism, form a glial sheath around sensory neurons of dorsal root ganglia (DRGs). SGCs show a presence of glutamine synthetase (GS) which transform uptaken Glu into gl...
Ginsenoside Rg2 alleviates neurovascular damage in 3xTg-AD mice with Alzheimer's disease through the MAPK-ERK pathway [0.03%]
Ginsenoside Rg2通过MAPK-ERK途径缓解3xTg-AD阿尔茨海默病小鼠的神经血管损伤
Xiaojun Ye,Sen Shao,Yanbo Wang et al.
Xiaojun Ye et al.
Alzheimer's disease (AD) is the most common form of dementia, and ginsenoside Rg2 (Rg2) is proven to inhibit AD's progression. This study investigates the potential benefits of Rg2 treatment on 3xTg-AD mice. Following 6 weeks of gavage trea...
Thimet oligopeptidase (THOP 1) distribution in cane toad (Bufo Marinus, Linnaeus, 1758) brain [0.03%]
澳洲蟾蜍大脑中Thimet寡肽酶（THOP 1）的分布
Diogo M L P Cavalcanti,Tiago S Teófilo,Tayline D Rodrigues et al.
Diogo M L P Cavalcanti et al.
Thimet oligopeptides (THOP 1) is a metal-dependent peptidase involved in the metabolism of neuropeptides and the presentation of peptides via MHC-1. It has been shown to play a role in the regulation of protein-protein interactions and the ...
Localization and neurochemical identity of alpha1-adrenergic receptor-containing elements in the mouse locus coeruleus [0.03%]
小鼠蓝斑中α1-肾上腺素能受体的定位及其神经化学特性
Zachary N M Luyo,Abigail B Lawrence,Theodore G Stathopoulos et al.
Zachary N M Luyo et al.
The locus coeruleus (LC) is the major source for norepinephrine (NE) in the brain and projects to areas involved in learning and memory, reward, arousal, attention, and autonomic functions related to stress. There are three types of adrener...