Christina Lillesaar
Christina Lillesaar
Neurons using serotonin (5-HT) as neurotransmitter and/or modulator have been identified in the central nervous system in representatives from all vertebrate clades, including jawless, cartilaginous and ray-finned fishes. The aim of this re...
VGF: an inducible gene product, precursor of a diverse array of neuro-endocrine peptides and tissue-specific disease biomarkers [0.03%]
VGF:一种可诱导的基因产物,多种神经内分泌肽和组织特异性疾病生物标志物的前体
Gian-Luca Ferri,Barbara Noli,Carla Brancia et al.
Gian-Luca Ferri et al.
The vgf gene (non-acronymic) is induced in vivo by neurotrophins including Nerve Growth Factor (NGF), Brain Derived Growth Factor (BDNF) and Glial Derived Growth Factor (GDNF), by synaptic activity and by homeostatic and other stimuli. Post...
Regulation of dorsal raphe nucleus function by serotonin autoreceptors: a behavioral perspective [0.03%]
五羟色胺自受体调节背缝核功能:行为学视角分析
Ross A McDevitt,John F Neumaier
Ross A McDevitt
Neurotransmission by serotonin (5-HT) is tightly regulated by several autoreceptors that fine-tune serotonergic neurotransmission through negative feedback inhibition at the cell bodies (predominantly 5-HT(1A)) or at the axon terminals (pre...
FoxP2 brainstem neurons project to sodium appetite regulatory sites [0.03%]
FoxP2脑干神经元投射至钠 Appetite调节部位
Jung-Won Shin,Joel C Geerling,Matthew K Stein et al.
Jung-Won Shin et al.
The transcription factor Forkhead box protein 2 (FoxP2) is expressed in two cell groups of the brainstem that have been implicated in sodium appetite regulation: the pre-locus coeruleus (pre-LC) and parabrachial nucleus--external lateral-in...
Social affiliation relates to tyrosine hydroxylase immunolabeling in male and female zebra finches (Taeniopygia guttata) [0.03%]
社交地位与环颈太平鸟的酪氨酸羟化酶免疫标记的关系研究
Sarah Jane Alger,Charity Juang,Lauren V Riters
Sarah Jane Alger
The catecholamines dopamine and norepinephrine are implicated in affiliative behaviors, yet few studies have addressed the extent to which affiliative behaviors within distinct social settings rely upon similar or distinct catecholaminergic...
Mariano Soiza-Reilly,Kathryn G Commons
Mariano Soiza-Reilly
The dorsal raphe nucleus (DR) contains the majority of serotonin (5-hydroxytryptamine, 5-HT) neurons in the brain that regulate neural activity in forebrain regions through their widespread projections. DR function is linked to stress and e...
Alteration of the CNS pathway to the hippocampus in a mouse model of Niemann-Pick, type C disease [0.03%]
Niemann-Pick C病鼠海马脑神经路径的改变
Kyunghee Byun,Joong-Mo Kim,Namhee Kim et al.
Kyunghee Byun et al.
Niemann-Pick type C disease (NPC) is an autosomal recessive disorder that results in premature death due to progressive neurodegeneration including dementia. To understand neuronal pathways connecting to the hippocampus, retrograde transneu...
Evidence demonstrating role of microRNAs in the etiopathology of major depression [0.03%]
微小核糖核酸在抑郁症发病机制中的作用证据
Yogesh Dwivedi
Yogesh Dwivedi
Major depression is a debilitating disease. Despite a tremendous amount of research, the molecular mechanisms associated with the etiopathology of major depression are not clearly understood. Several lines of evidence indicate that depressi...
Estrogen receptors stimulate brain region specific metabotropic glutamate receptors to rapidly initiate signal transduction pathways [0.03%]
雌激素受体通过刺激脑区特异性的代谢型谷氨酸受体来快速启动信号转导途径
John Meitzen,Paul G Mermelstein
John Meitzen
Estradiol and other steroid hormones modulate the nervous system and behavior on both acute and long-term time scales. Though estradiol was originally characterized as a regulator of gene expression through the action of nuclear estrogen re...
Kv3.1b and Kv3.3 channel subunit expression in murine spinal dorsal horn GABAergic interneurones [0.03%]
小鼠脊髓背角GABA能中间神经元表达Kv3.1b和Kv3.3通道亚单位
A Nowak,H R Mathieson,R J Chapman et al.
A Nowak et al.
GABAergic interneurones, including those within spinal dorsal horn, contain one of the two isoforms of the synthesizing enzyme glutamate decarboxylase (GAD), either GAD65 or GAD67. The physiological significance of these two GABAergic pheno...