Cleavage of semaphorin 4 C interferes with the neuroprotective effect of the semaphorin 4 C/Plexin B2 pathway on experimental intracerebral hemorrhage in rats [0.03%]
半导体素4C的裂解通过半导体素4C/plexin B2信号途径干扰半导体素4C对实验性脑出血的神经保护作用
Dong Li,Xiang Li Sr,Jiahe Wang et al.
Dong Li et al.
Semaphorin 4 C (SEMA4C) and its cognate receptor Plexin B2 are important regulators of axon guidance and are involved in many neurological diseases, in which SEMA4C acts not only as a ligand ("forward" mode) but also as a signaling receptor...
Aripiprazole attenuates the medial prefrontal cortex morphological and biochemical alterations in rats with neonatal ventral hippocampus lesion [0.03%]
阿立哌唑减轻新生 Ventral Hippocampus 损伤大鼠 medial prefrontal cortex 神经形态和生化改变
Gabriel D Flores-Gómez,David Javier Apam-Castillejos,Ismael Juárez-Díaz et al.
Gabriel D Flores-Gómez et al.
Schizophrenia is a neurodevelopmental disorder characterized by a loss of dendritic spines in the medial prefrontal cortex (mPFC). Multiple subclinical and clinical studies have evidenced the ability of antipsychotics to improve neuroplasti...
Caffeine alleviates anxiety-like behavior and brainstem lesions in a rotenone-induced rat model of Parkinson's disease [0.03%]
咖啡因通过缓解类似焦虑的行为和脑干损伤来治疗Rotenone诱导的大鼠帕金森病模型中的症状
Timileyin Adewumi Adeyeye,Bamidele Richard Babatunde,Samuel Ehimare Ehireme et al.
Timileyin Adewumi Adeyeye et al.
Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms. In 2016, approximately 6.1 million individuals were affected by PD, with 211,296 deaths attributed to the...
To what extent are orally ingested nanoplastics toxic to the hippocampus in young adult rats? [0.03%]
口服摄入的纳米塑料对年轻成年大鼠海马体的毒性程度如何？
Orhan Baş,Hasan İlhan,Hatice Hancı et al.
Orhan Baş et al.
As the use of plastic-containing materials in our daily lives becomes increasingly common, exposure to nanoplastics accordingly becomes inevitable. Micro and nanoplastics released from large amounts of plastic waste constitute a serious env...
Quercetin mitigates depression-like behavior via the suppression of neuroinflammation and oxidative damage in corticosterone-induced mice [0.03%]
檞皮素通过抑制神经炎症和氧化损伤缓解皮质酮诱导的小鼠抑郁样行为
Chenjie Ge,Shiliang Wang,Xuqi Wu et al.
Chenjie Ge et al.
Depression is a clinically common and easily overlooked mental disease. Quercetin is a flavonoid compound, which has anti-inflammatory and antioxidant roles. Previous reports presented the anti-depressant role of quercetin. Nevertheless, th...
Involvement of iNOS-induced reactive enteric glia cells in gastrointestinal motility disorders of postoperative Ileus mice [0.03%]
iNOS诱导的反应性肠胶质细胞在术后胃肠道运动障碍中的作用
Ailing Sun,An Hu,Jialing Lin et al.
Ailing Sun et al.
Postoperative ileus (POI) is the cessation or reduction of gastrointestinal (GI) motility after surgery. Reactive enteric glial cells (EGCs) are critical for maintaining bowel function. However, the triggering mechanisms and downstream effe...
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease [0.03%]
拉考沙胺在帕金森病大鼠模型中表现出神经保护作用
Burcin Bilal,Mehmet Kirazlar,Mumin Alper Erdogan et al.
Burcin Bilal et al.
Background: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that primarily affects the motor system. Although there are several treatments available to alleviate PD symptoms, there is curr...
The effects of myricitrin and chebulinic acid on the rat hippocampus exposed to gamma radiation: A stereological, histochemical and biochemical study [0.03%]
Sümeyye Gümüş Uzun,Berrin Zuhal Altunkaynak,Işınsu Alkan
Sümeyye Gümüş Uzun
Aim: Gamma radiation, a form of ionizing radiation, is used in many different areas, especially in the health field and in the treatment of cancer. However, gamma radiation used for therapeutic purposes also has numerous ...
Silymarin pretreatment protects against ethanol-induced memory impairment: Biochemical and histopathological evidence [0.03%]
奶蓟素预处理能对抗酒精所致的记忆力损害：生化和组织病理学证据
A Jabbari,B Alani,A Arjmand et al.
A Jabbari et al.
Background: Ethanol (Eth.) abuse induces memory impairment. Oxidative damage and apoptosis are considered the likely causes of memory impairment. Silymarin (Sil.) is a flavonoid isolated from the plant Silymarin marianum ...
Exosome-shuttled MYCBPAP from bone marrow mesenchymal stem cells regulates synaptic remodeling and ameliorates ischemic stroke in rats [0.03%]
骨髓间充质干细胞分泌的外泌体输送MYCBPAP调节突触重塑并改善缺血性卒中病理表型
Qiuyue Yan,Yong Yin,Xuechun Li et al.
Qiuyue Yan et al.
Background and purpose: Mesenchymal stem cells (MSC) have been demonstrated to improve cardiac function via the secretion of paracrine factors rather than direct differentiation. We, therefore, investigated whether bone m...