Long-term stability of dried blood spot samples for HIV diagnosis in adults from Kinshasa (Democratic Republic of Congo) [0.03%]
刚果民主共和国金沙萨成人HIV诊断DBS样本的长期稳定性研究
Nerea Astiz,Paula Martínez de Aguirre,Silvia Carlos et al.
Nerea Astiz et al.
Background: Dried blood spots (DBS) are a widely used sampling method for serological testing, particularly in resource-limited settings. However, long-term stability of HIV antibodies in DBS remains underexplored. This s...
Clinical evaluation of nasal swab specimens in VTM/UTM and RespDirect eSTM using the Panther Fusion SARS-CoV-2/Flu A/B/RSV assay [0.03%]
含病毒运输培养基和不含病毒运输培养基的鼻拭子样本在Panther Fusion SARS-CoV-2/流感A/B/RSV检测试剂盒中的临床评价
Salika M Shakir,Robert K McCall,Rangaraj Selvarangan et al.
Salika M Shakir et al.
Background: Respiratory viral infections by SARS-CoV-2, influenza A and B viruses, and RSV overlap in disease signs and symptomology, but differ in treatment modality. Nasal swab specimens have been shown to be an effecti...
External quality assessment for molecular detection of multiple respiratory pathogens in China [0.03%]
中国多重呼吸道病原体分子检测的室间质量评估
Xiaoyu Fan,Chunli Shi,Chengxiang Chu et al.
Xiaoyu Fan et al.
Background: Acute respiratory infections rank the fourth leading cause of mortality globally and impose a substantial burden on public health systems worldwide. Multiplex molecular assays have revolutionized the laborator...
Katelyn L Gough,Taylah K Anderson,David M Whiley et al.
Katelyn L Gough et al.
Human herpesvirus 6 (HHV-6) is a common virus which is typically acquired early in childhood, and like other herpesviruses, can induce lifelong latency. While healthy individuals are not at risk of disease, immunosuppressed individuals such...
Is there a need to repeat single assay reactive HIV screens? A review of practice in two UK sites [0.03%]
重复检测HIV初筛阳性结果的必要性——英国两地的做法及思考综述文章
Callum Goolden,Cheryl Williams,Sabeen Khurshid Zaidi et al.
Callum Goolden et al.
Background: In the United Kingdom, a 3-step algorithm for HIV screening is standard practice. Where there is discordancy between different serological assays, the interpretation of HIV status is challenging and guidance o...
Optimized respiratory virus influenza A whole genome sequencing strategies for improving even read coverage of segments [0.03%]
优化呼吸道病毒流感A全基因组测序策略以提高片段的均匀读取覆盖度
Ruimin Gao,Kennedy Irvine,Cody Buchanan et al.
Ruimin Gao et al.
Whole genome sequencing is increasingly being deployed to support respiratory virus influenza clinical studies and surveillance. However, PCR amplification inefficiency results in an imbalanced distribution among the eight segments, which m...
Fourth generation HIV rapid diagnostic test: Adequate sensitivity in HIV primary infection settings? [0.03%]
第四代HIV快速检测试剂盒的临床性能评价：在HIV急性期感染者中的敏感性探讨
Vincent Guiraud,Sofia Ben Attia,Nathalie Hamm et al.
Vincent Guiraud et al.
Background: HIV rapid diagnostic tests (RDT) enable easy point-of-care screenings but traditionally lack the HIV-1 p24-antigen detection, resulting in poor diagnostic window, up to three months after exposure. Fourth-gene...
Peptide-assisted direct detection of HPV nucleic acids from liquid-based cytology samples without extraction [0.03%]
用于液基细胞学样品的肽辅助直接检测HPV核酸方法无需提取步骤
Sadia Almas,Salima Karki,Rob E Carpenter et al.
Sadia Almas et al.
High-risk human papillomavirus remains the causal agent of nearly all cervical cancers. And we need tools for rapid detection that work in routinely taken samples (e.g., PreservCyt®) that can speed up, facilitate or simplify the extraction...
Head-to-head comparison of the performance of BIOFIRE® SPOTFIRE® Respiratory/Sore Throat Panel, Cepheid Xpert® Xpress SARS-CoV-2/Flu/RSV and Cobas® SARS-CoV-2 & Influenza A/B assay for detection of respiratory viruses [0.03%]
BIOFIRE SPOTFIRE 呼吸道/咽喉痛检测试剂盒、Cepheid Xpert Xpress SARS-CoV-2/Flu/RSV 和 Cobas SARS-CoV-2 & Influenza A/B 检测呼吸道病毒的性能对比研究
Dithi Banerjee,Anjana Sasidharan,Stephanie Gummersheimer et al.
Dithi Banerjee et al.
Background: We compared the performance of 3 multiplex respiratory platforms - BIOFIRE® SPOTFIRE® Respiratory/Sore Throat (R/ST) Panel (BioMérieux), Xpert® Xpress SARS-CoV-2/Flu/RSV assay (Cepheid) and Cobas® SARS-Co...
Bacterial colonization and life-threatening respiratory syncytial virus infection in children [0.03%]
儿童细菌定植和致死性呼吸道合胞病毒感染
Eduardo L López,Fausto Martín Ferolla,Agustina F Denardi et al.
Eduardo L López et al.
Background: Respiratory syncytial virus is a major cause of acute respiratory infection in children. While most cases are mild, some progress to life-threatening disease. The role of bacterial colonization in shaping resp...