Evaluation of the clinical and analytical performance of the LIAISON PLEX for the qualitative detection of human adenovirus in respiratory samples [0.03%]
LIAISON PLEX腺病毒II型呼吸道样本标本定性检测试剂盒临床及实验性能评估
Julie Norton,Omar Abdullah,Katharine Uhteg et al.
Julie Norton et al.
Background: Human adenoviruses (HAdVs) are significant causes of respiratory infections, which are most commonly associated with species B, C, and E. Certain adenovirus types are associated with higher mortality and outbr...
Enhanced HBcAg immunoassay enables detection of clinically relevant low-level HBV viremia for treatment eligibility [0.03%]
改良的HBcAg免疫测定法能够检测临床相关的低水平乙肝病毒血症以确定治疗资格
Rene Geissler,Megha Patel,Anika Koehler et al.
Rene Geissler et al.
Background: Accurate staging of chronic hepatitis B is essential for guiding treatment decisions and predicting clinical outcomes. Current treatment guidelines rely on HBV DNA quantification, with therapeutic thresholds s...
Next generation sequencing approaches for the detection and characterization of enteroviruses in clinical, public health, and research settings: Expert view of the European non-polio enterovirus network (ENPEN) [0.03%]
新型基因测序技术在临床、公共卫生及科研环境中检测和鉴别肠道病毒的应用：欧洲非脊髓灰质炎肠道病毒网络（ENPEN）专家视角
Kimberley S M Benschop,Florian Zwagemaker,Lili Andersson-Li et al.
Kimberley S M Benschop et al.
Enteroviruses (EVs) are a common cause of a wide spectrum of infectious diseases, ranging from mild respiratory illnesses to severe neurological conditions, particularly affecting children. Current molecular methods, such as 5'UTR-based PCR...
HIV-1 gag genotypic resistance testing using short-read and long-read next-generation sequencing technologies [0.03%]
基于短读和长读下一代测序技术的 HIV-1 型 gag 准基因耐药检测
Camille Vellas,Lila Poiteau,Stéphanie Raymond et al.
Camille Vellas et al.
Introduction: Lenacapavir is a new antiretroviral agent that targets the HIV-1 capsid, and is currently indicated for the treatment of patients with multidrug-resistant infection. It was recently approved by the U.S. Food...
Nipah virus molecular detection from whole blood and respiratory swabs in a rapid field-ready protocol [0.03%]
一种快速的现场检测方法可从全血和呼吸道取样拭子中鉴定尼帕病毒
Phuong-Vi Nguyen,Jayden Kimbro,Kumail Ahmed et al.
Phuong-Vi Nguyen et al.
Background: Nipah virus (NiV) is a highly pathogenic, zoonotic paramyxovirus with significant public health implications due to high associated mortality and potential for human-to-human transmission. Current diagnostic t...
Characterization of HIV humoral immunity during analytical treatment interruption [0.03%]
分析性治疗中断期间HIV体液免疫的特征研究
Clara Di Germanio,Brendan G Balasko,Patricia G Villaflor et al.
Clara Di Germanio et al.
Introduction: This study investigated whether HIV binding antibody (Ab) and p24 antigen (Ag) quantitation could detect humoral immune responses or p24 Ag before or following detectable plasma viral load (VL) rebound durin...
Early viral load outperforms cytokines and lymphocytes in predicting SFTS prognosis: A dynamic immune profiling study [0.03%]
早期病毒载量预测重型发热伴血小板减少综合征优于细胞因子和淋巴细胞：动态免疫谱分析研究
Keping Chen,Gan Cao,Yurong Xu et al.
Keping Chen et al.
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high mortality, yet its pathophysiology remains incompletely understood. To elucidate the immunopathogenesis and improv...
Virus-induced onychomadesis: Exploring the role of viral infection in nail shedding [0.03%]
病毒引起的甲脱落：探讨病毒感染在指甲脱落中的作用
Yingzi Cui,Pu Song,Xin Zhao et al.
Yingzi Cui et al.
Onychomadesis, characterized by proximal detachment of the nail plate due to temporary arrest of matrix proliferation, has been increasingly recognized as a complication following viral infections. Enterovirus-associated hand-foot-and-mouth...
Zoonotic influenza preparedness: Dutch medical labs efficiently detect animal influenza A viruses - External Quality Assessment, 2023 [0.03%]
人畜共患流感准备：荷兰医学实验室高效检测动物流感病毒——外部质量评估，2023年
Samantha Zoomer,Gabriel Goderski,Sharon van den Brink et al.
Samantha Zoomer et al.
Background: Since 2022, highly pathogenic H5N1 influenza A virus clade 2.3.4.4b has caused global outbreaks among wild birds and poultry, with increasing mammalian and sporadic human infections. This elevates concerns abo...
Use of PCR to exclude HIV-1 infection in high-risk patient populations following discordant serological results [0.03%]
应用PCR检测排除高危人群HIV-1感染的可能性及血清检测结果不一致的病例
Rachael M Tomb,Rory N Gunson
Rachael M Tomb