Resolving the clinical dilemma of low positive HIV screening: 2-mercaptoethanol as the optimal pretreatment over polyethylene glycol precipitation to safeguard early diagnosis [0.03%]
解决HIV筛查阳性率低的临床难题：优化早期诊断的乙二醇预处理方法优于聚乙二醇沉淀法
Ling Qin,Ping Zhang,Haifeng Yan et al.
Ling Qin et al.
Background: The high sensitivity of fourth-generation HIV antigen/antibody combo assays leads to a substantial number of low-positive screening results, creating a diagnostic dilemma. Guidelines suggest polyethylene glyco...
Comparison of influenza hemagglutination inhibition titers from capillary blood versus venipuncture [0.03%]
指尖采血与静脉穿刺获得的流感单抗效价比较分析
Anne-Marie Rick,Rachel Costa,John F Alcorn et al.
Anne-Marie Rick et al.
Background: Capillary blood self-collection devices offer a minimally invasive alternative to venipuncture, potentially expanding access to serologic studies in outpatient and remote settings. We aimed to evaluate the con...
Letermovir prophylaxis timing in standard-risk and very high-risk adult CMV-seropositive allogeneic hematopoietic stem cell transplant recipients: A systematic literature review [0.03%]
成人巨细胞病毒阳性异基因造血干细胞移植受者的勒特莫韦预防性治疗时间：一项系统文献回顾
Luxiang Wang,Yi Sun,Jiaxian Guo et al.
Luxiang Wang et al.
Cytomegalovirus (CMV) infection remains a major complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). We conducted a systematic review of 34 studies including 3489 CMV-seropositive adult allo-HSCT recipients who...
Global trends in norovirus genotype distribution among medically attended children with acute gastroenteritis, 2020-2025 [0.03%]
2020至2025年全球医学就诊儿童急性胃肠炎诺如病毒基因型分布趋势分析
Jennifer L Cannon,Joseph Bonifacio,Tulio M Fumian et al.
Jennifer L Cannon et al.
Background: Norovirus is a leading cause of acute gastroenteritis, with a broad diversity of genotypes infecting children. NoroSurv is an established global network for norovirus strain surveillance among medically attend...
Evaluation of a modified 2-step diagnostic algorithm for human immunodeficiency virus type 1 utilizing an HIV-1/2 antigen/antibody immunoassay screen and an HIV nucleic acid amplification test [0.03%]
评估利用HIV-1/2抗原/抗体免疫检测试验筛查和HIV核酸扩增试验的两步式改良诊断算法的价值
Tessa M Shates,Kimberly Macias,Susan Realegeno et al.
Tessa M Shates et al.
Introduction: A multi-test algorithm is routinely used for HIV-1 diagnosis. Guidelines recommend an HIV-1/2 antigen/antibody (Ag/Ab) immunoassay screen that reflexes reactive samples to an HIV-1/2 antibody differentiation...
Newborn screening dried blood spots enable population-level measurement of RSV immunity [0.03%]
新生儿干血滴纸片筛查能进行人群水平的RSV免疫检测
Xiaoqing Dang,Jacob Shew,Marina Viñeta Paramo et al.
Xiaoqing Dang et al.
Background: Respiratory syncytial virus (RSV) is the leading cause of respiratory infection in young children. Although passive immunization strategies are available for infants, the relationship between population immuni...
ONWARD: A one health, pan-European multidisciplinary network advancing surveillance, research, clinical management and control of zoonotic hepeviruses [0.03%]
“ONWARD：一个促进欧洲人畜共患HEPE病毒监测、研究、临床管理和控制的多学科网络”
Antonio Rivero-Juarez,Branko Velebit,Reimar Johne et al.
Antonio Rivero-Juarez et al.
Zoonotic hepeviruses, particularly hepatitis E virus (HEV, species Paslahepevirus balayani) represent a major yet underestimated public health challenge in Europe. Despite being the leading cause of acute viral hepatitis, surveillance, diag...
Human parechovirus infection in neonates and young infants: Clinical features, diagnostic challenges, and neurodevelopmental outcomes [0.03%]
新生儿和婴幼儿人 Parechovirus 感染的临床特点、诊断困难及神经发育结局
Giacomo Brisca,Marcello Mariani,Tommaso Bellini et al.
Giacomo Brisca et al.
Human parechoviruses (HPeVs) are increasingly recognized as viral pathogens in neonates and young infants. Among the 18 identified genotypes, HPeV-3 is most strongly associated with severe disease during early infancy, including sepsis-like...
Esophageal papillomas and human papillomavirus infection: A case series, scoping review and analysis [0.03%]
食道乳头状瘤和人类乳头瘤病毒感染：病例系列、综述及分析
Maximilian Egg,Werner Dolak,Behrang Mozayani et al.
Maximilian Egg et al.
Background: Human papillomaviruses (HPVs) have been implicated in the development of papillomatous proliferations in the esophagus. In 2013, the HPV detection rate in esophageal squamous papillomas (ESPs) was estimated at...
Development and genomic characterization of a diverse HIV-1 variant reference panel for nucleic acid-based testing [0.03%]
用于核酸检测的HIV-1多样变体参考菌株的开发及基因组表征
Jiangqin Zhao,Tianxiong Li,Hanxia Huang et al.
Jiangqin Zhao et al.
Background: The high worldwide genetic diversity of HIV poses significant challenges for its detection and diagnosis by nucleic acid testing (NAT). Well-characterized reference panels are important for evaluating the anal...