Yan Su,Lei Zhou
Yan Su
Enhancing the sensitivity of immunoassays is an important requirement in the field of immunology, especially in light of rapid developments in genetic testing, making the detection of low-abundance protein biomarkers crucial. Therefore, inn...
Studying drug excretion into exhaled breath aerosol - A workflow based on an impaction sampling device and LC-HRMS/MS analysis [0.03%]
基于撞击式采样装置和LC-HRMS/MS分析的呼出气溶胶中药物排泄研究
Juel Maalouli Schaar,Michael Kunz,Lea Wagmann et al.
Juel Maalouli Schaar et al.
Background: Exhaled breath (EB) aerosol was in principle shown to be a suitable matrix for bioanalysis of volatile but also non-volatile compounds. This attracted particular interest in the field of drug analysis. However...
Improving insights from metabolomic functional analysis combining multivariate tools [0.03%]
结合多元统计工具提高代谢功能分析质量
Julia Kuligowski,Marta Moreno-Torres,Guillermo Quintás
Julia Kuligowski
Background: Metabolomics is a scientific field that relies on the comprehensive analysis of metabolites to provide direct insights into functional processes in biological systems. Metabolomic data provides valuable insigh...
A biosensor integrating the electrochemical and fluorescence strategies for detection of aflatoxin B1 based on a dual-functionalized platform [0.03%]
一种集成电化学和荧光策略的生物传感器用于检测基于双功能平台的黄曲霉毒素B1
Hamidreza Rahmanian,Mitra Malekkiani,Mehdi Dadmehr et al.
Hamidreza Rahmanian et al.
Background: Aflatoxin B1 (AFB1), is a potent hepatic carcinogen which causes cancer by inducing DNA changes in the liver cells. Variety of methods have been developed for detection of AFB1 which are based on single mode d...
Multifunctional Fe3O4@CuS nanoparticle-driven colorimetric and photothermal immunochromatographic test strip for the sensitive detection of Salmonella typhimurium in milk [0.03%]
一种灵敏检测牛奶中鼠伤寒沙门氏菌的多功能Fe3O4@CuS纳米粒子驱动的比色和光热免疫试纸条
Hong Duan,Xuan Wang,Haichuan Li et al.
Hong Duan et al.
Magnetic nanoparticles are widely employed as signal labeling reporters in immunochromatographic test strips (ICTS) for detecting foodborne pathogens due to their outstanding anti-interference and magnetic enrichment performance. However, t...
Determinations of methylmercury and mercury methylation/demethylation rate constants in environmental samples using isotope dilution/tracing methods by automatic ethylation-purge and trap-GC-ICP-MS [0.03%]
采用自动乙基化吹扫捕集-气相色谱-电感耦合等离子体质谱法同时进行环境样品中甲基汞的同位素稀释/示踪及其甲基化/去甲基化反应速率常数测定
Yandong Liu,Xueyu Guo,Jinqian Ju et al.
Yandong Liu et al.
Background: Mercury (Hg), especially methylmercury (MeHg) as a most toxic format of Hg in the environment, has been paid widely concern due to its high bioaccumulative capability and great risk to humans. Great efforts ha...
Development of a CZE-MS/MS method with dynamic pH junction sample pretreatment for analysis of kratom psychoactive alkaloids in urine [0.03%]
基于尿液样品动态pH界面上样的CZE-MS/MS分析坤蒂树叶精神活性生物碱的方法开发
Andrea Horniakova,Peter Mikus,Juraj Piestansky
Andrea Horniakova
Background: Kratom is a herbal substance belonging to the group of new psychoactive substances. It contains psychoactive indole alkaloids mitragynine and 7-hydroxymitragynine. At low doses, they act as psychostimulants an...
An integrated CBLA-Net with fractional discrete wavelet transform and frequency-based CARS to predict heavy metal elements by XRF [0.03%]
基于分数离散小波变换和频率CARS的集成CBLA-Net预测XRF光谱中的重金属元素含量模型
Wanqi Yang,Fusheng Li,Qinglun Zhang et al.
Wanqi Yang et al.
Background: X-ray fluorescence (XRF) emerges as a promising technique for estimating heavy metal elements. However, XRF spectra typically contain a significant amount of environmental information and signal noise, and the...
Triple-helix molecular-switch-actuated rolling circle amplification and catalytic hairpin assembly multistage signal amplified fluorescent aptasensor for detection of aflatoxin B1 [0.03%]
三链分子开关激活的滚环扩增和催化发夹组装多级信号放大荧光适配子传感器检测黄曲霉毒素B1
Liuyi Zhang,Huali Jin,Zhen Zhang et al.
Liuyi Zhang et al.
Background: Mycotoxins, a class of secondary metabolites produced by molds, are widely distributed in nature and are very common in food contamination. Aflatoxin B1 (AFB1) is a highly stable natural mycotoxin, and many ag...
Colorimetric detection of furin based on enhanced catalytic activity of G-quadruplex/hemin DNAzyme [0.03%]
基于G-四联体/血红素DNA酶增强催化活性的色彩检测法检测furin酶
Liu Shi,Lin Wang,Xiaomeng Yu et al.
Liu Shi et al.
Background: Rapid and sensitive colorimetric detection methods are crucial for diseases diagnosis, particularly those involving proteases like furin, which are implicated in various conditions, including cancer. Tradition...