Simultaneous multi-biomarker detection: streptavidin-biotin mediated high-quality quantum dot immunosensor with signal amplification [0.03%]
基于链霉亲和素-生物素信号放大的量子点免疫传感器高效检测多种生物标志物
Huanhuan Xing,Ruixue Zhang,Ning Li et al.
Huanhuan Xing et al.
Background: Developing highly sensitive, high-throughput, and multiplexed detection methods for tumor markers is critical for early cancer diagnosis. Traditional streptavidin-biotin (SA-biotin) quantum dot (QD) immunoassa...
Amino-blocking sialic acid linkage specific alkylamidation for qualitative and quantitative analysis of sialylated glycoproteins [0.03%]
N-氨基保护型特异乙酰化分析去唾液酸糖蛋白的方法及装置
Wanwei Luo,Zhixin Tian
Wanwei Luo
Protein glycosylation is a pivotal post-translational modification involved in diverse physiological processes. Sialic acid, a terminal monosaccharide in glycans, exhibits critical biological functions and disease associations, yet its link...
Method development and production of an ambient-stable blood certified reference material for total mercury, methylmercury, and trace elements [0.03%]
一种用于总汞、甲基汞和痕量元素检测的稳定的血液认证参考材料的方法开发与制备
Koichi Haraguchi,Mineshi Sakamoto,Hiromitsu Nagasaka et al.
Koichi Haraguchi et al.
Background: Certified reference materials (CRMs) for mercury speciation of biological fluids have hitherto been limited to frozen or cold-storage types, which impedes the participation of laboratories in tropical or remot...
Direct quantification of thallium(I) in water by ESI-MS via supramolecular recognition with cryptand[2.2.2] [0.03%]
应用超分子识别技术直接通过ESI-MS定量测定水中的铊离子
Hai Li,Ping Guo,Min Li et al.
Hai Li et al.
Background: Thallium, a highly toxic heavy metal, is widely distributed in the environment. The substance poses a grave threat to human health through contamination of the food chain, drinking water, and environmental exp...
Corrigendum to "Immunomagnetic hydrogel nanofibrils for exosomes isolation" [Anal. Chim. Acta 1406 (2026) 345484] [0.03%]
“用于外泌体分离的免疫磁性水凝胶纳米纤维”的订正(实验室研究)
Xiaorong Song,Mingyang Li,Wenya Chang et al.
Xiaorong Song et al.
Published Erratum
Analytica chimica acta. 2026 Aug 1:1409:345571. DOI:10.1016/j.aca.2026.345571 2026
In-column click chemistry for preparation of octadecyl spherical covalent organic framework modified silica reversed-phase mode stationary phase [0.03%]
柱内点击化学制备十八烷基球状共价有机骨架修饰硅胶反相模式固定相
Yanyu Jiang,Wenlong Yuan,Jie Wen et al.
Yanyu Jiang et al.
Background: The common method for grafting various groups on the covalent organic framework (COF) modified silica is post-modification reaction, which often occurs in round-bottom flask. However, the reaction in round-bot...
Comparing capillary coatings for protein separation by capillary electrophoresis [0.03%]
比较用于蛋白质分离的毛细管电泳的涂层毛细管
Alisa Höchsmann,Christina Sejling,Laura Dhellemmes et al.
Alisa Höchsmann et al.
For intact protein separation by capillary electrophoresis, the application of a proper capillary coating is crucial to achieve high separation efficiencies. There are a large number of different capillary coatings and coating protocols, ma...
Comparative Study
Analytica chimica acta. 2026 Aug 1:1409:345561. DOI:10.1016/j.aca.2026.345561 2026
A time-efficient cyclic ion mobility spectrometry-mass spectrometry method for the separation and detection of ergot alkaloids [0.03%]
一种高效的时间循环离子移动性谱-质谱法分离和检测麦角生物碱类化合物的方法
Laura Carbonell-Rozas,Ane Arrizabalaga-Larranaga,Laura Righetti
Laura Carbonell-Rozas
Background: The diversity of ergot alkaloids (EAs) isomers poses significant challenges for traditional analytical methodologies. By adding an orthogonal rapid gas-phase separation step, Ion mobility mass spectrometry (IM...
ZIF-8 functionalized alginate-chitosan hybrid microspheres as a versatile platform for α-glucosidase immobilization and high-throughput inhibitor screening [0.03%]
基于海藻酸钠壳聚糖复合微球的金属有机骨架ZIF-8在α-葡萄糖苷酶固定化及高效抑制剂筛选中的应用
Haodong Zhou,Lijing Lei,Xiangze Fan et al.
Haodong Zhou et al.
Background: Efficient immobilization of α-glucosidase (α-Glu) is crucial for its application in inhibitor screening, but conventional polysaccharide hydrogels suffer from limited mechanical strength and stability. We hy...
Electrochemical strategies for lateral flow and LAMP-Based platforms toward pathogen detection: A critical review [0.03%]
用于侧向流动和LAMP平台的电化学策略以检测病原体：批判性评论
Lucas F de Lima,Paulo Felipe Neves Estrela,Leonardo Lopes-Luz et al.
Lucas F de Lima et al.
Background: The integration of lateral flow assays (LFAs) with loop-mediated isothermal amplification (LAMP) has gained increasing attention in analytical and bioanalytical chemistry for rapid and sensitive pathogen detec...