A triarylboron-based fluorescence probe for distinguishing inflammatory and tumor cells by imaging mitochondrial DNA and hypochlorite with different signal emission characteristics [0.03%]
一种三芳基硼基荧光探针通过不同信号发光特性区分开发炎细胞和肿瘤细胞的线粒体DNA和次氯酸成像
Xufeng Nie,Sijie Yan,Ruixue Gan et al.
Xufeng Nie et al.
Background: Mutations in the mitochondrial DNA (mtDNA) are linked to hereditary diseases and serve as danger associated molecular patterns involved in inflammation, autoimmunity, and aging. Mitochondrial HClO is particula...
Electrochemical biosensor with custom fluidics for amplification-free, low-picomolar DNA detection [0.03%]
一种用于无扩增低皮摩尔DNA检测的电化学生物传感器及其定制流体系统
Tina D&#x;Aponte,Maria De Luca,Elisabetta de Alteriis et al.
Tina D&#x;Aponte et al.
Background: The sensitive and rapid detection of low-concentration DNA sequences in complex biological matrices remains a critical need across biomedical, environmental, and food sectors. While amplification-based techniq...
Resonance-matched terahertz metamaterials integrated with IRFE-MLR framework enabling specificity-enhanced detection of trace pefloxacin [0.03%]
基于IRFE-MLR框架并实现特异性增强的跟踪检测培氟沙星共振匹配太赫兹超材料
Lintong Zhang,Jingsen Yang,Jiachen Zhang et al.
Lintong Zhang et al.
Background: Pefloxacin (PEF), a widely used broad-spectrum antimicrobial, garners considerable scientific concern due to its inherent biotoxicity and potential risk of antibiotic resistance gene transfer. Current detectio...
Mitochondrial targeting ratiometric theranostic probe activated by hydrogen peroxide toward tracking pH variations in therapeutic processes [0.03%]
一种过氧化氢激活的线粒体靶向治疗诊断比率型探针用于追踪治疗过程中的PH变化
Yan Zhang,Huifeng Zhang,Jing He et al.
Yan Zhang et al.
Background: At present, cancer remains one of the most devastating health challenges worldwide. Its high mortality rate, metastatic potential, and resistance to conventional treatments make it particularly lethal. Under t...
A Raman-microfluidic system for single bacterium identification, and sorting, and its application in bacterial properties analysis [0.03%]
一种用于单细菌识别和分选的拉曼微流控系统及其在细菌属性分析中的应用研究
Zixin Shu,Xiaoyu Zhang,Fengyi Li et al.
Zixin Shu et al.
Background: Rapid and reliable bacterial detection is very important for both disease diagnosis and bacterial research, but the speed of bacterial detection is greatly affected by the fact that traditional detection metho...
A new AgTe0.08S1.67 QDs-based fluorescence sensing platform for rapidly detect UO22+ in water environment [0.03%]
一种新型AgTe0.08S1.67量子点荧光检测平台用于快速检测水体中的UO₂²⁺离子
Huan Yang,Danyan Lin,Jie Yang et al.
Huan Yang et al.
Background: Uranium is a vital element in energy and military applications but poses significant environmental and health risks due to its toxicity, radioactivity, and long half-life. During its use, uranium waste is rele...
A smartphone-integrated colorimetric and fluorescent sensor for monitoring salmon freshness [0.03%]
一种智能手机集成的比色及荧光传感器用于监测三文鱼新鲜度的研究
Xiaofei Sun,Nan Ren,Huihui Gong et al.
Xiaofei Sun et al.
Background: Salmon is a tasty and nutritious fish that is widely welcomed by consumers worldwide. However, salmon is susceptible to spoilage and generates biogenic amines (BAs), which are detrimental to human health upon ...
A pre-training enhanced deep learning framework for robust sparse unmixing in chemical imaging [0.03%]
一种用于化学影像稳健稀疏解混的预训练增强深度学习框架
Yue Wang,Anqi Liu,Lin Tan et al.
Yue Wang et al.
Background: Chemical imaging techniques, such as hyperspectral and Raman imaging, provide spatially resolved spectral insights for non-destructive analysis of complex mixtures. However, accurately decomposing mixed pixel ...
Deep eutectic solvent based on primary amine and terpenoid for smartphone-based colorimetric determination of polyDADMAC in water samples [0.03%]
基于伯胺和萜烯的地阻溶剂在智能手机比色测定水样中聚DADMAC中的应用
Maria Kochetkova,Alena Antonova,Irina Timofeeva et al.
Maria Kochetkova et al.
Background: Water quality is critically important for the global environment and public health. Polydiallyldimethylammonium chloride is cationic polyelectrolyte which acts as a flocculant and coagulant, helping to purify ...
Machine learning-assisted affinity ultrafiltration for bioactive natural products discovery:Application to screening of neuraminidase inhibitors from medicinal herbs [0.03%]
机器学习辅助亲和超滤技术在生物活性天然产物发现中的应用：中药神经氨酸酶抑制剂筛选案例研究
Menghan Chen,Shengyong Ding,Liqing Wang et al.
Menghan Chen et al.
Background: Bioactive natural products represent a vital resource for combating human diseases. However, their discovery often encounters multiple challenges. Bioactivity-guided isolation can yield bioactive compounds but...