Silver amplified immunosensor via effective fluorogenic Ag+-imidazole aggregation for detection of AFB1 [0.03%]
一种有效检测AFB1的银增强免疫传感器及其荧光法测定方法
Xufang Huang,Xiaorui Xing,Pixian Zhang et al.
Xufang Huang et al.
Background: Cereals are susceptible to aflatoxin contamination during storage and transportation, which is highly carcinogenic and teratogenic, and seriously threaten human health. The accurate and rapid detection of tota...
Fluorescent labeling of live-cell surfaceome and its application in antibody-target interaction analysis [0.03%]
活细胞表面组的荧光标记及其在抗体靶标相互作用分析中的应用
Haoting Wang,Ying Zhang,Wenchao Wang et al.
Haoting Wang et al.
Background: Cell-surface proteins play key roles in the communication between external stimuli and internal signaling. As protein types and expression levels vary in different cells, in-situ visualization of the whole sur...
Analyte-induced hindrance in the RCA-assisted CRISPR/Cas12a system for homogeneous protein assays [0.03%]
分析物引起的RCA辅助CRISPR / Cas12a系统均相蛋白质测定中的空间位阻效应
Guobin Mao,Qiaoyu Li,Ziying Zhang et al.
Guobin Mao et al.
Heterogeneous assays, such as enzyme-linked immunosorbent assays, have become indispensable for in vitro diagnostics. However, the simple, sensitive, and accurate detection is limited by their multiple washing and incubation steps, and limi...
Deactivated fused silica tubing: A solution for flexible time weighted averaging needle trap sampling [0.03%]
用于柔性时间加权平均针陷阱采样的去活化熔融石英管
Hasan Javanmardi,Mohit Singh,Janusz Pawliszyn
Hasan Javanmardi
In time-weighted averaging (TWA) with needle trap extraction (NTE), the control of the sampling rate is critical for accurate analysis. By adjusting the diffusion length and cross-sectional area, the sampling rate can be modified in accorda...
Localized hybridization chain reaction amplifier utilizing three-dimensional DNA nanostructures for efficient and reliable microRNA imaging in living cells [0.03%]
利用三维DNA纳米结构的局部化杂交链反应放大器对活细胞中微小核糖核酸进行高效和可靠的成像
Bingyu Yang,Xiang Gao,Hengxin Yu et al.
Bingyu Yang et al.
MicroRNAs (miRNAs) are pivotal in regulating biological processes such as cell proliferation and disease progression. Traditional miRNA detection methods like qRT-PCR and Northern blotting do not allow for monitoring dynamic changes in livi...
A novel variable selection algorithm based on neural network for near-infrared spectral modeling [0.03%]
一种基于神经网络的新型变量选择近红外光谱建模算法
Pengfei Zhang,Zhuopin Xu,Huimin Ma et al.
Pengfei Zhang et al.
Background: Partial least squares (PLS) is a widely used technique for modeling spectral data. Researchers have developed numerous PLS-based variable selection algorithms to enhance model predictive ability and interpreta...
Daedu Lee,Yoonsoo Pang
Daedu Lee
Background: Chiral-selective molecular interactions are considered crucial in numerous physiological processes. Chiral-selective analytical methods of biomolecules with sufficient sensitivity are of great interest in nume...
A novel nucleic acid extraction system integrating a switching valve-assisted microfluidic cartridge and a constant pressure pump [0.03%]
一种新型核酸提取系统，集成切换阀微流控卡匣和恒压泵
Jiujian Zhou,Anzhong Hu,Jun Zhao et al.
Jiujian Zhou et al.
Background: Nucleic acid extraction (NAE) is essential in molecular diagnostics, genetic engineering, and DNA sequencing. While advances in switching valve-assisted, self-contained microfluidic (S2M) cartridges have impro...
Troy T Handlovic,M Farooq Wahab,Bailey C Glass et al.
Troy T Handlovic et al.
Background: In the past three decades, liquid chromatography (LC) has been recognized as a significant environmental, health, and safety burden due to its heavy reliance on toxic organic solvents. Various chromatographic ...
Atomically Fe(Ⅲ) anchored metal-organic frameworks-based fluorescent nanozyme for smartphone-adopted chemiluminescence-fluorescence dual-mode analysis of Uric acid [0.03%]
基于原子级Fe(Ⅲ)锚定的金属有机框架的荧光纳米酶的智能手机化学发光-荧光双模尿酸分析法
Jing Wang,Shuijian He,Haiyan Zhang et al.
Jing Wang et al.
Background: Chemiluminescence (CL) analysis is a promising analytical method with advantages including easy operation, high sensitivity and simple instrument. However, the single CL mode usually suffered from poor stabili...