Recent advances in nanoscale metal-organic frameworks (nanoMOFs) for electrochemical pharmaceutical sensing: a review [0.03%]
纳米金属有机框架（nanoMOFs）在电化学药物传感中的最新进展：综述
David Valero-Calvo,Diego Alvarez-Rafael,Elena Lastra et al.
David Valero-Calvo et al.
Electroanalytical methods have emerged as powerful alternatives for pharmaceutical compounds detection due to their high sensitivity, rapid response, portability, and cost-effectiveness. Among advanced functional materials, nanoscale metal-...
Quantitative assessment of neutrophil chemotactic migration under coexisting intermediate and terminal chemokine gradients in a microfluidic environment: Applications for immune dysfunction and prognostic evaluation in sepsis [0.03%]
微流控环境下联合存在中继型和终端型细胞趋化因子梯度的中性粒细胞化学趋向运动的定量评估：脓毒症免疫功能障碍及预后评价中的应用
Zhuoyi Zhu,Xiao Yang,Yuhang Yao et al.
Zhuoyi Zhu et al.
Background: Sepsis remains a life-threatening condition, largely due to immune dysregulation and the difficulty of accurately assessing patient prognosis. Neutrophils, as central innate immune effectors, migrate through c...
Environmental microbial bioprospecting enabled by a Raman fingerprinting and functional sorting on a microfluidic static droplet array [0.03%]
基于拉曼指纹识别和微流体静态液滴阵列功能分选的环境微生物生物探测技术
Guoxia Zheng,Yanwen Liu,Huicheng Chen et al.
Guoxia Zheng et al.
Function-driven microbial bioprospecting has been hindered by persistent trade-offs among throughput, resolution, and cell viability in current single-cell analysis technologies. To overcome these limitations, we developed MicroSD-RFFS, a p...
Tracer-assisted shotgun lipidomics (TASL): A quantitative workflow integrating stable-isotope tracing with global lipidome profiling [0.03%]
基于稳定同位素追踪的脂质组学定量化工作流程(TASL)
Hashmatullah Nasimi,Lya K K Holland,Knut K B Clemmensen et al.
Hashmatullah Nasimi et al.
Background: Shotgun lipidomics provides a quantitative, steady-state overview of global lipidomes, but offers limited insight into metabolic dynamics. Tracer lipidomics yields time-resolved quantitative information on spe...
Dual-layer N-glycoproteomics enhances resolution of serum glycosylation signatures in type 2 diabetes mellitus complicated with coronary heart disease [0.03%]
双层N-糖蛋白组学增强了解析2型糖尿病合并冠心病血清糖基化标志物的分辨率
He Zhang,Jueping Chen,Yuxuan Chen et al.
He Zhang et al.
Protein glycosylation presents profound analytical challenges due to its structural heterogeneity, yet robust workflows capable of resolving glycosite- and glycan-level information within complex clinical cohorts remain limited. To address ...
Electrochemical discrimination of phenylalanine enantiomers in blood using an ATO-γ-CD nanocomposite-modified SWCNT platform [0.03%]
基于ATO-γ-CD纳复合材料修饰的SWCNT手性电极的血浆中L-DOPA动态检测研究
Ionela Raluca Comnea-Stancu,Raluca-Ioana Stefan-van Staden,Jacobus Koos Frederick van Staden
Ionela Raluca Comnea-Stancu
Background: The biological sciences and medical disciplines demand the development of an electrochemical approach for enantiomer identification that is both efficient and easy. Phenylalanine enantiomers, require sensitive...
Label-free and isothermal multiplex detection of miRNAs using self-priming hairpin probes and light-up aptamer transcription [0.03%]
基于自引物发夹探针和核酸适配体转录的链上报告基团的恒温多miRNA检测新方法
Hyogu Han,Hyo Won Jeon,Jieun Yang et al.
Hyogu Han et al.
Background: MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression and serve as valuable biomarkers for the early diagnosis and prognosis of various diseases, including cancer. However, conventional...
Synthesis of rhodamine modified carbon quantum dots and application of ratiometric fluorescence detection for Cu2+ and triple-mode detection for 2,4-dichlorophenoxyacetic acid [0.03%]
罗丹明修饰碳量子点的合成及其比率型检测铜离子和2,4-二氯苯氧乙酸的三模式荧光传感研究
Qing Li,Yage Guan,Qian Wang et al.
Qing Li et al.
Background: 2,4-Dichlorophenoxyacetic acid (2,4-D) is a widely used herbicide whose environmental residues pose threats to ecology and health. Copper ions (Cu2+), as common heavy metal pollutants, can exhibit synergistic ...
A semi-supervised domain adaptation framework with attention-enhanced ResNet50 for LIBS-based soil classification under spectral distribution shift [0.03%]
基于LIBS的土壤分类光谱分布转移下的半监督领域自适应框架及注意力增强ResNet50算法
Yihua He,Yu Ding,Xiangchu Li et al.
Yihua He et al.
Background: Laser-induced breakdown spectroscopy (LIBS), as a rapid and non-destructive analytical technique, has been widely applied in soil classification research. In recent years, the integration of LIBS with deep lea...
Molecularly imprinted polymer nanoparticle-based sequential competitive fluorescence assay for serum ferritin assessment [0.03%]
基于分子印迹聚合物纳米颗粒的顺序竞争性荧光法测定血清铁蛋白
Sanita Singsanan,Thanet Prajantasen,Rungthiwa Niamlaoong et al.
Sanita Singsanan et al.
Background: The protein ferritin indicates the amount of iron reserves stored in the body and is crucial for diagnosing iron-deficiency anemia and assessing iron overload. Immunoassays, which depend on the selective inter...