An LC-MS-guided AI enabled serum molecule-interpretable SERS platform for exploratory metabolomic analysis in Alzheimer's disease [0.03%]
基于LC-MS引导的AI增强型血清分子可解释SERS平台用于阿尔茨海默病探索性代谢组学分析
Yanling Wang,Chi Zhang,Tong Liu et al.
Yanling Wang et al.
Label-free surface-enhanced Raman spectroscopy (SERS) offers a promising avenue for rapid metabolic phenotyping in complex biofluids, yet its translational potential is hindered by the challenge of deconvoluting overlapping spectral contrib...
Fluorescent sensor array for rapid and accurate multiplexed pathogen identification [0.03%]
用于快速、准确的病原体多重鉴定的荧光传感器阵列
Siyuan Huang,Yuqing Hu,Hongyu Wang et al.
Siyuan Huang et al.
Background: The challenge of antimicrobial resistance is caused by delayed and inaccurate pathogen identification. It results in the existing diagnostic methods being unable to guide the appropriate use of antibiotics. Th...
Dual-mode MXene-based biosensor coupled with machine learning: a smart sensing strategy for detection of zearalenone in food [0.03%]
基于MXene的双模式生物传感器结合机器学习：一种智能检测食品中玉米赤霉烯酮的策略
Shi Feng,Yijing Wang,Yanyan Shang et al.
Shi Feng et al.
Background: Zearalenone (ZEN) is a potent endocrine disruptor that poses serious health risks through reproductive toxicity. Traditional detection methods, including high-performance liquid chromatography (HPLC), fall sho...
Biomimetic solid phase microextraction as a tool for quantifying organic micropollutants-biopolymer partitioning [0.03%]
仿生固相微萃取技术在有机微量污染物-生物聚合物分配研究中的应用
Nipunika H Godage,Madison L Williams,Emanuela Gionfriddo
Nipunika H Godage
Background: Understanding the partitioning behavior of emerging organic micropollutants (OMPs) into naturally occurring biopolymers is critical for assessing their environmental transport, bioavailability, and fate. Howev...
A matrix-tolerant one-dimensional CNN for raw LIBS analysis: Architecture and soil carbon benchmark [0.03%]
一种用于原生LIBS分析的矩阵容限一维CNN：架构与土壤碳基准
Heloisa V Guilherme,Paulino R Villas-Boas
Heloisa V Guilherme
Background: Matrix effects, line overlap, and weak signals limit quantitative accuracy in Laser-Induced Breakdown Spectroscopy (LIBS), especially for heterogeneous samples such as soils. Conventional pipelines rely on ext...
Twenty years of ASCA: a systematic review of applications for ANOVA-simultaneous component analysis [0.03%]
ASCA二十年回顾：对ANOVA-同时成分分析应用的系统性综述
Daniel Schorn-García,Giulia Gorla,Jokin Ezenarro
Daniel Schorn-García
Background: ANOVA-simultaneous component analysis (ASCA) integrates ANOVA-based variance decomposition with latent variable modelling to quantify, validate and interpret factor-related variation in high-dimensional analyt...
ATP-responsive NIR-Ⅱ fluorescence/mass spectrometry dual-modal nanoprobe for precision diagnosis of metabolic dysfunction-associated steatohepatitis [0.03%]
一种用于精准诊断代谢紊乱相关脂肪肝炎的ATP响应型近红外二区荧光/质谱双模态纳米探针
Fei Huang,Quan Jing,Ningli Wang et al.
Fei Huang et al.
Background: Metabolic dysfunction-associated steatohepatitis (MASH) requires analytical tools capable of noninvasive and dynamic evaluation of hepatic metabolic dysfunction in vivo. Adenosine triphosphate (ATP) is a key i...
Duplex DNase-powered RNA walker for multiplex fluorescent detection of trace pesticide residues in tea samples [0.03%]
用于茶叶样品中痕量农药残留的多重荧光检测的双功能DNase驱动RNA行走器
Fang Guo,Wenjiao Zhou,Xia Li
Fang Guo
Background: The bipyridine herbicide paraquat (PQ) and the benzimidazole fungicide carbendazim (CBZ) play a key role in weed and fungus control on farmlands to elevate crop output. Yet, excessive deployment of these chemi...
Cathodic aggregation-induced electrochemiluminescence sensor based on trinuclear iridium complexes for sensing Cu2+ ions [0.03%]
基于三核铱配合物的阴极聚集增强型电致化学发光铜离子传感器
Shili Hou,Wei Li,Jiali Li et al.
Shili Hou et al.
Aggregation-induced emission (AIE) metal complexes overcome the limitation of aggregation-caused quenching (ACQ) of materials and become a class of promising electrochemiluminescence (ECL) emitters in the field of sensing. However, the cath...
Laser-induced flexible Cu@NC/graphene electrode integrated with smartphone for on-site and non-enzymatic glucose monitoring [0.03%]
基于智能手机的现场及非酶型血糖检测用激光制备柔性Cu@NC/石墨烯电极
Quan Yang,Peng Liu,Wuyi Wang et al.
Quan Yang et al.
Background: Accurate, rapid and on-site quantification of glucose (Glu) is crucial for the management of diabetes and its complications as well as food safety monitoring. Electrochemical sensors for non-enzymatic Glu quan...