Systematic method optimisation approach for small molecule imaging on the SELECT SERIES MALDI MRT - Drug mapping in fingerprints, a case study [0.03%]
小分子成像的系统方法优化方案——以SELECT SERIES MALDI MRT指纹药物图谱为例
Rohith Krishna,James Langridge,Emmanuelle Claude et al.
Rohith Krishna et al.
Molecular fingerprinting via Matrix Assisted Laser Desorption Ionisation time-of-flight Mass Spectrometry profiling (MALDI MSP) and Imaging (MALDI-MSI) has been proven to provide biometric and lifestyle information from a fingermark. As suc...
Plasmon-enhanced fluorescence sensor based on Au nanocages for sensitive detection of norepinephrine [0.03%]
一种基于金纳米笼的等离激元增强型荧光传感器用于检测去甲肾上腺素
Chenye Xu,Shilin Chen,Wen Sun et al.
Chenye Xu et al.
Background: Norepinephrine (NE) as a crucial monoamine neurotransmitter in the central and sympathetic nervous system, plays an important role in different physiological and pathophysiological processes. Brain NE can modu...
Introducing an algorithm to accurately determine copolymer block-length distributions [0.03%]
介绍一种准确确定共聚物嵌段长度分布的算法
Rick S van den Hurk,Ynze Mengerink,Ron A H Peters et al.
Rick S van den Hurk et al.
Background: Copolymers are attractive for developing advanced materials with widespread applications such as medical devices, implants, or self-healing coatings for space stations and satellites. Their physical properties...
Engineering- nanochannels with pH-responsive gates for direct detection of glucose in human blood serum [0.03%]
具有pH响应门的纳米流通道用于直接检测人血清中的葡萄糖浓度
Yinde Wu,Jialun Li,Yunzhou Chen et al.
Yinde Wu et al.
Background: An abnormal blood glucose (Glu) level is a key signal of diabetes. The gluconic acid produced by Glu catalytic oxidation can cause changes in pH value. ...
A novel biosensor MDC@N-MMCNs to selective detection and elimination of foodborne bacterial pathogens [0.03%]
用于选择性检测和消除食源性细菌病原体的新生物传感器MDC@N-MMCNs
Shuyue Sun,Yonglin Feng,Haonan Li et al.
Shuyue Sun et al.
Background: Infections caused by foodborne pathogens pose a major threat to human health. Traditional bacterial detection methods, such as plate culture and polymerase chain reaction, cannot meet the growing demand for fa...
Gas-liquid chromatography as a tool to determine vapor pressure of low-volatility pesticides: A critical study [0.03%]
气液色谱法测定低挥发性农药蒸汽压的研究
Clara Parzanese,Carlina Lancioni,Cecilia Castells
Clara Parzanese
Background: The vapor pressure of pesticides at room temperature is one of the fundamental properties for predicting their volatilities and the likelihood of their movement into the environment. It is also highly valuable...
Online multimethod platform for comprehensive characterization of monoclonal antibodies in cell culture fluid from injection of crude sample - Incorporation of middle-up and bottom-up workflows [0.03%]
一种在线多方法平台,用于从粗略样本注射的细胞培养液中对单克隆抗体进行综合特征分析- 中上游和下游工作流程的结合
Raya Sadighi,Vera H de Kleijne,Marek Vido et al.
Raya Sadighi et al.
Background: Determination of critical quality attributes (CQAs) of pharmaceutical monoclonal antibodies (mAbs) is an essential part of quality control. Commonly, for each CQA, a separate analytical method and setup is req...
Electrochemical detection of creatinine at picomolar scale with an extended linear dynamic range in human body fluids for diagnosis of kidney dysfunction [0.03%]
用于诊断肾功能障碍的人体液中皮摩尔范围的肌酐电化学检测(扩展线性动态范围)
Sanya Khursheed,Sumera Sarwar,Dilshad Hussain et al.
Sanya Khursheed et al.
Background: Creatinine levels in different body fluids can serve as an important biomarker for kidney functioning relevant to prostate cancer and chronic kidney disease (CKD). Creatinine levels vary in concentration in di...
Multi-nanozyme cascade system for boosting colorimetric sensing by selective etching bimetallic MOFs [0.03%]
选择性蚀刻双金属MOF的多纳米酶级联系统用于增强比色传感
Yuhang Lin,Tianshuo Wang,Yuanhao Liu et al.
Yuhang Lin et al.
Background: Rational engineering of multienzyme system architecture is essential for achieving high-performance multi-enzyme cascade catalysis in sensing applications. In this context, the initiation step of the cascade r...
Raman spectroscopic detection of synthetic cannabinoid-related 1H-indazole-3-carboxamide on seized paper stamps: A forensic challenge in providing nondestructive analyses and feasible counterevidence [0.03%]
拉曼光谱在缴获的邮票状合成大麻素制品中检测1H-吲哚并[3,2-a]咔啉-3-甲酸胺:提供无损分析和可行反证的法医学挑战
Luciano S F Silva,Lucas S Abreu,Eliani Spinelli et al.
Luciano S F Silva et al.
Background: Synthetic cannabinoids challenge forensic laboratories, which typically rely on sample-consuming chromatography-mass spectrometry. Criminalistic regulations mandate preserving seized material for potential jud...