A parallel reaction monitoring-mass spectrometric method for studying lipid biosynthesis in vitro using 13C16-palmitate as an isotope tracer [0.03%]
使用13C16棕榈酸同位素示踪剂体外研究脂质生物合成的平行反应监测-质谱法
Kyeong-Seog Kim,Young Gyun Ko,Woo Seok Yang et al.
Kyeong-Seog Kim et al.
Background: Palmitate, which is the end product of fatty acid synthase, is the key fatty acid for understanding of lipid biosynthetic process in mammalian cells. Mass spectrometry (MS) methodology using 13C-palmitate can ...
Optimization, validation, and implementation of a new method for detecting liquid crystal monomers in dust using GC-MS/MS with atmospheric pressure chemical ionization [0.03%]
基于大气压化学电离的气相色谱-质谱联用测定灰尘中液晶单体的新方法的优化、验证及应用研究
Jing Han,Jun Liu,Huiyuan Lu et al.
Jing Han et al.
Background: Liquid crystal monomers (LCMs) are a new class of emerging pollutants. To assess their occurrence, behaviour, and potential risks, a sensitive and selective analytical method is required for the determination ...
PCR-based SNP genotyping: A comprehensive comparison of methods for affordable and accurate detection of class IV mutations [0.03%]
基于PCR的SNP基因分型：针对IV类突变低成本和精确检测方法的全面比较
Kajan Muneeswaran,Varuni A de Silva,Umayal Branavan et al.
Kajan Muneeswaran et al.
Single nucleotide polymorphisms (SNPs) influence gene function and impact health and disease. Identifying and genotyping SNPs is crucial in various areas of research and applications. This study compared five PCR-based methods for detecting...
Comparative Study
Analytica chimica acta. 2025 Jun 8:1354:343994. DOI:10.1016/j.aca.2025.343994 2025
Identification of microplastics and nanoplastics in environmental water by AFM-IR [0.03%]
AFM-IR识别环境水中的微塑料和纳米塑料
Dandan Xie,Huiyao Fang,Xia Zhao et al.
Dandan Xie et al.
Background: Microplastics and nanoplastics have gained worldwide attention as environmental hazards, and reliable analysis of these tiny particles is critical to accurate assessment of their impact to the environment and ...
Chlorine-functionalized black phosphorus quantum dots induced superoxide anion generation and depletion for efficient chemiluminescence detection [0.03%]
氯功能化黑磷量子点诱导超氧阴离子生成及消耗的高效化学发光检测方法研究
Hui Gong,Dayang Zhao,Houjing Liu
Hui Gong
Background: Due to their unique optoelectronic properties, environmental friendliness, and excellent biocompatibility, metal-free quantum dots have been a new star in exploring novel chemiluminescence (CL) systems for ana...
Instant synthesis of bimetallic CuCo PBA nanozyme for efficient colorimetric immunoassay of carcinoembryonic antigen [0.03%]
瞬时合成双金属CuCo PBA纳米酶高效比色法测定癌胚抗原免疫分析
Xiaoqin Li,Huizi Lin,Xuwei Chen et al.
Xiaoqin Li et al.
Colorimetric immunoassays are widely used for biomarker detection, offering advantages of simplicity, sensitivity, and cost-effectiveness. Recent advancements focus on improving the catalytic activity of nanozymes for enhancing the sensitiv...
Rational design and pairing of single-domain antibodies for developing rapid detection methods for botulinum neurotoxins A and B [0.03%]
针对肉毒神经毒素A型和B型快速检测方法的单域抗体理性设计与配对
Ruomei Lv,Jiaxin Li,Xinyu Fang et al.
Ruomei Lv et al.
Background: Botulinum neurotoxin (BoNT) is a toxin produced by Clostridium botulinum that can cause neurological dysfunction in humans and animals, with BoNT/A and BoNT/B being responsible for the majority of poisoning ca...
Rapid identification of multiplexed pathogens via a two-step dual-channel fluorescence turn-on array [0.03%]
通过两步双通道荧光开启阵列快速鉴定多重病原体
Xingliang Huang,Yang Yu,Huihai Li et al.
Xingliang Huang et al.
Bacterial infections have been an increasingly serious threat to human health. However, the rapid identification of multiplexed bacteria remains challenging due to their intricate composition. Herein, we developed a two-step, dual-channel f...
Assembling metal nanoclusters with high luminescence performance and anti-interference ability for sensing p-nitrophenol [0.03%]
高性能抗干扰金属纳米簇的组装及比色检测痕量p-硝基苯酚
Jiaxi Wang,Jiaqing Li,Yuexiang Lu et al.
Jiaxi Wang et al.
Background: The fluorescence quantum yield (QY) of water-soluble gold nanoclusters (AuNCs) can be prominently improved by adding l-arginine (Arg) owing to rigidifying ligands. However, these fluorescence systems exhibit p...
A prototype low-pressure assisted microwave plasma ionization mass spectrometry for on-line monitoring of organic and inorganic hazardous compounds simultaneously: Design and feasibility validation [0.03%]
一种低气压辅助微波等离子体电离质谱联用技术在线监测有机及无机危害物的可行性研究：装置设计与实验验证
Gaosheng Zhao,Yuliang Huang,Bin Jia et al.
Gaosheng Zhao et al.
Background: The detection of harmful atmospheric gases, including inorganic small molecules (e.g., hydrogen sulfide, H2S) and volatile organic compounds (VOCs) such as aromatic hydrocarbons, is crucial due to their involv...