AFM-optimized single-cell level LA-ICP-MS imaging for quantitative mapping of intracellular zinc concentration in immobilized human parietal cells using gelatin droplet-based calibration [0.03%]
基于明胶液滴的校正法优化原子力显微镜，用于单细胞水平激光消融电感耦合等离子体质谱成像，绘制人壁细胞中细胞内锌浓度分布图
Valerie Boger,Philip Pirkwieser,Noreen Orth et al.
Valerie Boger et al.
Background: Quantitative bioimaging of trace elements at the single-cell level is crucial for understanding cellular processes, including metal uptake and distribution. Laser ablation inductively coupled plasma mass spect...
Single-well colorimetric sensor array for discrimination and smartphone-assisted detection of catecholamines based on Fe-carbon dots nanozymes [0.03%]
基于Fe-碳点纳米酶的单井比色传感器阵列的多巴胺类物质识别及智能手机辅助检测技术
Guang-Ming Bao,Dan-Dan Chen,Yi-Fan Xia et al.
Guang-Ming Bao et al.
Background: Catecholamines (CAs), such as noradrenaline (NE), adrenaline (AD), and dopamine (DA), are essential signaling mediators that regulate various physiological functions. Monitoring their levels is crucial for stu...
Yixi Shi,Haonan Li,Hao Chen et al.
Yixi Shi et al.
Background: Microfluidic paper-based analytical devices (μPADs) and microfluidic thread-based analytical devices (μTADs) have already found many successful applications in biosensing. These devices mainly utilize the au...
Carbon quantum dots-based fluorescent probe for sensitive and selective detection of glutathione in bacteria and cells [0.03%]
一种用于细菌和细胞中谷胱甘肽灵敏检测的碳量子点荧光探针
Lina Wu,Huangpei Xiao,Jiaxin Xue et al.
Lina Wu et al.
Background: The sensitivity of 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) method may not be enough to detect low concentration glutathione (GSH), especially in complex samples, which limits its application in some biolog...
Systematic characterisation of microplastics released from disposable medical devices using laser direct infrared spectroscopy [0.03%]
采用激光直接红外光谱法对一次性医疗器械释放的微塑料进行系统表征
Chuanfeng Chen,Shanshan Du,Ziyan Liu et al.
Chuanfeng Chen et al.
Background: Human exposure to microplastics (MPs) is widespread, attracting significant attention from both the public and the scientific community. Although several direct and indirect exposure pathways have been investi...
Boosted synergistic catalytic performance of Pt single-atom catalyst NiS2/Pt on wearable hydrogel biosensor for sweat lactic acid analysis [0.03%]
基于可穿戴水凝胶生物传感器的Pt单原子催化剂NiS2/Pt协同催化的汗液乳酸分析增强性能研究
Cuncun Wang,Yong Zhang,Xin Zeng et al.
Cuncun Wang et al.
Background: Lactic acid is an important biochemical marker for monitoring tissue oxidation, as its buildup can lead to soreness, fatigue, and potentially serious. Sweat lactic acid detection typically relies on lactic aci...
Yue Cao,Dipesh Khanal,Adrian Cernescu et al.
Yue Cao et al.
Bacteriophage (phages) are naturally occurring nanoscale antimicrobial agents that can self-replicate at infection sites and selectively eliminate pathogenic bacteria. Significant heterogeneity exists in phage properties such as morphology,...
Shear flow deformability cytometry: A microfluidic method advancing towards clinical use - A review [0.03%]
剪切流变变形细胞分析法：一种面向临床应用的微流体技术——综述
Lija Fajdiga,Špela Zemljič,Tadej Kokalj et al.
Lija Fajdiga et al.
Background: Shear flow deformability cytometry is an emerging microfluidic technique that has undergone significant advances in the last few years and offers considerable potential for clinical diagnostics and disease mon...
Label-free detection of E. coli by alternating current electrokinetic capacitive sensors [0.03%]
基于交变电流电导效应的大肠杆菌无标记检测传感器研究
Xingchi Liu,Xinchen Qiu,Zhang Pan et al.
Xingchi Liu et al.
Background: Escherichia coli (E. coli) is one of the most common pathogens in water and foods, and it poses a significant threat to global public health, particularly in low- and middle-income countries. However, most of ...
Classification of urinary stones using near-infrared spectroscopy and chemometrics: A promising method for intraoperative application [0.03%]
基于近红外光谱的尿石分类：一种有前景的术中应用方法
Ekaterina Boichenko,Mikhail Paronnikov,Anna Reznichenko et al.
Ekaterina Boichenko et al.
In low-invasive surgical treatment of urolithiasis, there is a need for an analytical method to determine the chemical composition of urinary stones in real-time mode, i.e., intraoperatively. While a thorough phase analysis can be done afte...