Automated microfluidic-based polyurethane/lactate oxidase-chitosan/m-phenylenediamine biosensing platform for lactate monitoring in breast cancer cell culture [0.03%]
一种用于乳腺癌细胞培养基中乳酸检测的自动化微流控聚氨酯/乳酸氧化酶-壳聚糖/对苯二胺生物传感平台
Hnin Thandar Lwin,Kewarin Phonklam,Thanaporn Khunpitak et al.
Hnin Thandar Lwin et al.
Background: Lactate is a significant indicator of cancer characteristics. Monitoring lactate dynamics in cell metabolism provides crucial insights into cellular events, essential for developing novel therapeutic strategie...
The catalytic hairpin assembly induces a conformational change of the RNA aptamer enabled in situ imaging of circRNAs in tumor cells [0.03%]
催化发夹装配用于诱导RNA适配子的构象变化并在肿瘤细胞中进行circRNA的原位成像
Yanheng Yao,Feifan Yin,Qiufeng Wang et al.
Yanheng Yao et al.
Circular RNAs (circRNAs) are ubiquitously expressed across all cell types and tissues, playing a pivotal role in regulating diverse biological processes and being implicated in various human cancers. Their inherent stability renders them hi...
I Giménez,G Sormani,A Rodríguez et al.
I Giménez et al.
Background: The development of selective materials for radionuclide separation is often a long and costly process, requiring labor-intensive chemical separations and extensive optimization. To streamline the development o...
Real-time amplification and high resolution melt analysis on a rapid microfluidic instrument [0.03%]
一种快速微流体装置实现的实时扩增和高分辨率熔解分析方法
Renna L Nouwairi,Killian C O&#x;Connell,Rachelle A Turiello et al.
Renna L Nouwairi et al.
Background: Real-time nucleic acid amplification represents a robust, ubiquitous technology that often requires additional downstream analysis to identify sequence polymorphisms or differentiate specific from non-specific...
Bead-free digital enzyme-linked immunoassay on PDMS microwell array [0.03%]
基于PDMS微孔阵列的免手工操作数字酶联免疫吸附试验
Han Wu,Huaiheng Zhou,Zhanqiang Sun et al.
Han Wu et al.
Background: Proteins which are important biomarkers for disease diagnosis, prognosis and treatment are often present at very low concentrations in biological samples. Measuring these low-level proteins is important yet ch...
Functional data analysis, a comprehensive framework for processing non-quadrilinear and low-selective data provided by four-way liquid chromatography analysis [0.03%]
功能性数据处理，四维色谱分析所提供非矩形和低选择性数据的全面框架
Mirta R Alcaraz,Milagros Montemurro,Pablo L Pisano et al.
Mirta R Alcaraz et al.
The chemometric treatment of higher-order chromatographic (LC) data often crashes due to two main effects: the chromatographic band shifts/warpings across samples and quasi-full overlaps between component signals, affecting their analytical...
Self-assembled TMB-CuO2 nanosheets for dual-mode colorimetric and NIR-II photothermal detection of uranyl ion [0.03%]
一种用于检测尿anyl离子的双模式彩色和近红外光热纳米片传感器
Yingying Wu,Xiaofeng Tan,Hongyu Gong et al.
Yingying Wu et al.
Background: The development of highly sensitive and selective point-of-care testing (POCT) techniques using optical methods for uranyl ion (UO22+) is essential for the effective monitoring of acidic uranium contamination....
Label-free urinary protein detection through machine learning analysis of single droplet evaporation patterns [0.03%]
基于单液滴挥发图谱的机器学习无标记尿蛋白检测技术
Ruyue Yang,Nannan Cao,Yan Yang et al.
Ruyue Yang et al.
Background: Chronic kidney disease (CKD) is a major global public health issue, with a steadily increasing incidence. Urinary protein detection serves as a crucial indicator for the diagnosis, monitoring and management of...
Lab-made open-source controlled robotic workstation for sorbent-based dispersive microextraction of low-volume samples [0.03%]
基于吸附剂分散微萃取的低体积样品分析的实验室开放式控制机器人工作站
Guillem Peris-Pastor,Jose Grau,Luis Arruza et al.
Guillem Peris-Pastor et al.
Background: Despite microextraction techniques have gained prominence over traditional extraction ones, they usually involve repetitive and tedious manual procedures. Full or partial automation could help alleviate this d...
Ultrasensitive detection of methamphetamine in environmental water bodies by an Au@carbon dots/chitosan nanocomposite modified electrochemical aptasensor [0.03%]
一种用于环境水体中美沙酮超灵敏检测的电化学适配子传感器
Chunying Yuan,Mushui Shu,Caini Yang et al.
Chunying Yuan et al.
Background: The robust analytical methods for methamphetamine (METH), the second most widely used illicit drug globally, in aqueous environments are essential for on-site detection of regional drug abuse and pollution, an...