Development of a miniaturized chemiluminescence lateral flow immunoassay platform with ultra-high sensitivity and ultra-low background for cardiac troponin I [0.03%]
一种超灵敏和极低背景心肌肌钙蛋白I化学发光层析免疫测定芯片的开发
Zixuan Ren,Yue Cui
Zixuan Ren
Background: Lateral flow immunoassays (LFA) are widely used for disease diagnostics due to their simplicity and portability. However, they often suffer from limited sensitivity and accuracy, making them unsuitable for qua...
Enzymatic hydrolysis combined with chemiluminescence immunoassay: Foresight for automated and rapid urinary aldosterone detection [0.03%]
基于酶解与化学发光免疫分析的尿液醛固酮自动化快速检测新方法学展望
Jian Zhong,Honglei Li,Yicong Yin et al.
Jian Zhong et al.
Background: The 24-hour urinary aldosterone test offers superior stability in assessing aldosterone secretion compared to single-point plasma measurements, suggesting its potential utility as a diagnostic tool for primary...
Development and validation of a thermal desorption method based on Py-GC-HRMS using in-house reference materials to quantify a set of additives in polypropylene [0.03%]
基于Py-GC-HRMS的热解吸方法的发展和验证，使用内部参考材料量化聚丙烯中一组添加剂的数量
Saïd Rekibi,Robert Heidrich,Anton Mordvinkin et al.
Saïd Rekibi et al.
Background: Plastic additives, such as plasticizers, flame retardants, and UV stabilizers, significantly enhance polymer properties but pose health and environmental risks due to their potential migration into food produc...
Synergistic HRP/Biotin encapsulation in DNA nanoflowers via RCA: A path to stabilized, streamlined ELISA platform [0.03%]
通过RCA在DNA纳米花中协同封装HRP/生物素：简化和稳定的ELISA平台的一条路径
Xinglin Wu,Chengqun Chen,Chenchen Lin et al.
Xinglin Wu et al.
Background: Enzyme-linked immunosorbent assay (ELISA) requires the simultaneous maintenance of enzyme activity and the efficient labelling of the enzymes on the antibodies. Challenges in ELISA include the enzyme decomposi...
An integrated biosensor and mobile workstation for on-site species and sex identification from bloodstains [0.03%]
一种集成式生物传感器和移动工作站，在现场从血迹中鉴定物种和性别
Huyun Zhou,Wenjing Hu,Jiaxing Zhang et al.
Huyun Zhou et al.
Bloodstains are the most common biological specimens at a crime scene. Rapid and sensitive species and sex identification from bloodstains can expedite crime investigation. Nevertheless, time-consuming protocols and specialized equipment ar...
Small-molecule fluorescent probes for imaging intracellular amyloid toxicity induces ferroptosis via HClO fluctuation in Alzheimer's disease [0.03%]
用于成像淀粉样毒性通过HClO波动在阿尔茨海默病中诱导铁死亡的小分子荧光探针
Wenhui Ma,Bingbing Tang,Han Zhang et al.
Wenhui Ma et al.
Background: Amyloid toxicity induces ferroptosis play a crucial role in the pathological dysfunction of brains affected by Alzheimer's disease (AD). Despite this, brain probing implements for looking into the relationship...
Porphyrin based hydrogen bond organic frameworks as enhanced ECL luminophore for the ultrasensitive detection of breast cancer 1 gene [0.03%]
基于氢键有机框架的卟啉增强型发光材料用于乳腺癌1基因超灵敏检测
Jin-Jie Pan,Mi Chen,Hao-Tian Zhu et al.
Jin-Jie Pan et al.
The demand for high-performance electrochemiluminescence (ECL) emitters in aqueous media continues to grow due to requirements for ultrasensitive biomedical detection. In this work, we report the synthesis of Zn (II) meso-tetra(4-carboxyphe...
A Bayesian Adaptive Clustered Prior Learning (ACPL) method for sparse spectroscopic regression [0.03%]
一种贝叶斯稀疏光谱回归自适应聚类先验学习方法研究
Pengcheng Wu,Youhui Jiang,Tao Chen et al.
Pengcheng Wu et al.
Background: As regression techniques are increasingly developed and deployed in spectroscopic analysis, we have seen increasing implementation in many scientific and engineering disciplines. Therefore, ensuring their reli...
Green solvent boosts fluorescence of copper nanoclusters: Achieving ultra-fast fabrication of a universal sensing platform for H2O2-related biomarkers detection [0.03%]
一种绿色溶剂增强铜纳米团簇荧光：实现超快通用型过氧化氢相关生物标志物检测传感平台的制备
Yuanyuan Wang,Ziwei Ren,Feng Liang et al.
Yuanyuan Wang et al.
Background: Copper nanoclusters (Cu NCs) exhibit considerable potential for biosensing applications. However, their practical application is hindered by low fluorescence emission intensity and inadequate stability. Conven...
Orthogonal signal-transducing electrochemical dual-aptasensor for ultrasensitive parallel detection of GP73 and AFP in serum [0.03%]
用于平行检测血清中GP73和AFP的正交信号转导型电化学双重适配子传感器
Xiaohong Tan,Bo Wang,Xuyang Chen et al.
Xiaohong Tan et al.
Background: Golgi protein 73 (GP73) has emerged as a promising serological biomarker for hepatocellular carcinoma (HCC), with its combination with alpha-fetoprotein (AFP) substantially improving diagnostic precision in ea...