Engineering antibody conjugation and valency for optimized nanoparticle-based immunoassays [0.03%]
基于纳米粒子的免疫测定中工程化抗体偶联和价态以实现优化
Tong He,Gelin Liu,Yanwen Zhao et al.
Tong He et al.
Background: The introduction of nanoparticles (NPs) has led to substantial improvements in the performance of immunoassays. However, the further development of NP-based immunoassays is hampered by the lack of precise conj...
Hollow MOFs-based biomimetic encoded microspheres as versatile probes for dual-mode ratiometric fluorescence sensing platform coupling instrumental and smartphone-assisted analysis of Sudan I [0.03%]
基于中空MOF的仿生编码微球作为构建双模式比值型荧光检测平台的通用探针用于苏丹红I的仪器及手机辅助检测
Xueyong Qiao,Rongrong Yang,Zhonghui Han et al.
Xueyong Qiao et al.
Background: The accurate, ultrasensitive, and on-site detection of pollutants is critical for public health. As a carcinogen, Sudan I is strictly forbidden from use in food products at any levels. However, the conventiona...
Nanobody-HRP fusion-based competitive immunoassay for rapid and sensitive serological detection of porcine deltacoronavirus [0.03%]
一种用于快速灵敏检测猪δ冠状病毒的纳米抗体-HRP融合蛋白竞争法免疫检测方法
Chengyao Hou,Lijun Zhao,Runmin Kang et al.
Chengyao Hou et al.
Background: Nanobodies (Nbs), single-domain antibodies derived from camelid heavy-chain antibodies, possess high stability, strong affinity, and cost-effective production, making them attractive recognition elements for b...
Corrigendum to "Antioxidant 3-hydroxyflavone analogues: Integrated experimental and theoretical insights into lead fluoro-sensing and toxicity mitigation in living systems" [Analyt. Chim. Acta 1385 (2026) 344996] [0.03%]
关于“抗氧化3-羟基黄酮类似物：引领荧光传感和生物系统中毒性缓解的实验与理论洞察”的勘误(分析化学 acta 1385 (2026) 344996)
Trisha Samanta,Partha Chakrobarty,Suktara Guria et al.
Trisha Samanta et al.
Published Erratum
Analytica chimica acta. 2026 Mar 8:1390:345134. DOI:10.1016/j.aca.2026.345134 2026
Double derivatization-enhanced LC-MS/MS for isomer-resolved identification and quantification of fatty acids [0.03%]
双衍生化增强的液相色谱-串联质谱法实现脂肪酸异构体分辨定性与定量分析
Xingyu Shi,Xuan Liang,Shuilin Xie et al.
Xingyu Shi et al.
Background: Fatty acids (FAs) are essential metabolites involved in energy storage, signaling, and inflammation regulation, and their biological functions are closely linked to the position and geometric configuration of ...
In-situ laser-induced metal (M = Fe, Co, Ni, Cu)-doped graphene electrode for sensitive uric acid sensing in sweat [0.03%]
原位激光诱导金属(M=Fe、Co、Ni和Cu)掺杂石墨烯电极用于汗液中尿酸的灵敏检测
Nannan Ma,Qilin Liu,Nianyang Cai et al.
Nannan Ma et al.
Background: Laser-induced graphene (LIG) technology has demonstrated considerable promise for the fabrication of wearable electrochemical sensing devices. However, the pristine LIG typically exhibits suboptimal electroche...
Separation-free enantiodiscrimination of chiral pesticides via dual-stereocenter 19F NMR probes for multicomponent and environmental analysis [0.03%]
用于多组分和环境分析的双手性中心19F NMR探针的手性农药非分离对映体识别
Xin Zhang,Guangxing Gu,Jiajin Weng et al.
Xin Zhang et al.
Background: Chiral pesticides are increasingly important in agrochemicals, with enantiomers differing significantly in bioactivity, toxicity, and environmental impact. Rapid and robust methods for resolving these enantiom...
High-throughput copper speciation with SEC-UV-ICPMS: Insights from Wilson's disease mouse models [0.03%]
高效液相结合ICPMS法分析铜离子的价态：威士尼病小鼠模型中的研究进展
Yu Zhang,Xueqing Zhao,Beth Crowell et al.
Yu Zhang et al.
Background: Wilson's disease (WD) is a genetic disorder caused by ATP7B gene mutations, impairing copper excretion and leading to toxic copper accumulation in vital organs. Inductively coupled plasma mass spectrometry (IC...
Implications of specific ion effects on salt-induced proteome precipitation in organic solvent [0.03%]
特定离子对有机溶剂中盐致蛋白质沉淀的影响
Ziheng Dang,Jessica L Nickerson,Alan A Doucette
Ziheng Dang
Background: Solvent-based protein precipitation is an integral component of the proteomics workflow, as a means of concentrating and purifying proteins ahead of digestion and mass spectrometry. We previously disclosed the...
A high-throughput detection platform for dried blood spots constructed with DESI-MS/MS [0.03%]
基于DESI-MS/MS的干血斑高通量检测平台构建方法
Siqi Gao,Jinhui Zhao,Yue Guan et al.
Siqi Gao et al.
Background: Dried blood spot (DBS) technology, as a method of blood collection and preservation, has the advantages of small blood collection, convenient transportation and avoiding the degradation of metabolites. In part...