Equidistant regions of interest - multivariate curve resolution for clean spectra from plant-metabolomics by gas chromatography with high resolution mass spectrometry [0.03%]
等距区域感兴趣区-气相色谱高分辨质谱获得的植物代谢洁净光谱的多变量曲线解析法
Zhuang Gao,Xianghui Yao,Yimin He et al.
Zhuang Gao et al.
Background: The application of Gas Chromatography coupled with Orbitrap High-Resolution Mass Spectrometry (GC-Orbitrap HRMS) in plant metabolomics presents challenges including substantial data storage requirements, syste...
Locally-weighted-RoBoost-PLS: a multivariate calibration approach to simultaneously cope with non-linearities and outliers [0.03%]
局部加权RoBoost-PLS simultaneous处理非线性和离群点的多元校正方法
Daniele Tanzilli,Lorenzo Strani,Maxime Metz et al.
Daniele Tanzilli et al.
Background: Partial Least Squares regression (PLS) is a widely used tool for predictive modelling, particularly when dealing with multivariate datasets with dependent variables exhibiting strong collinearities. However, w...
Lipid droplet-targeting fluorescent probes for monitoring hydrogen sulfide in ferroptosis [0.03%]
用于铁死亡中监测硫化氢的脂滴靶向荧光探针
Chen Wang,Zhaomin Wang,Bingyan Li et al.
Chen Wang et al.
Background: Ferroptosis represents a unique form of regulated cell death that is distinct from apoptosis, necroptosis, and other modalities. It is characterized by iron-dependent lipid peroxidation and the depletion of gl...
Multi-functional dumbbell DNA probe design and its application in signal amplification cascade -based assay of human immunodeficiency virus [0.03%]
多功能哑铃状DNA探针设计及其在信号放大级联通量测定人类免疫缺陷病毒中的应用
Yan Gao,Yifei Li,Qian Gao et al.
Yan Gao et al.
Sensitive assay of Human immunodeficiency virus (HIV) is the premise of accurate prevention and con-trol of AIDS. Dumbbell DNA showed promising potential in biosensing, imaging applications. This study presents a highly sensitive biosensing...
Automatised online SPE-LC-MS/MS method for the enantioselective determination of chiral β-blockers and antidepressants in wastewater [0.03%]
用于废水中共旋光学β受体阻滞剂和抗抑郁剂的手性enantioselective测定的自动化在线SPE-LC-MS/MS方法
Marina Arenas,Julia Martín,Juan Luis Santos et al.
Marina Arenas et al.
Background: Pharmacologically active compounds are emerging pollutants of greatest concern because of their continuous release to the aquatic media and potential effects on non-target organisms. Nevertheless, in spite tha...
A portable point-of-care testing platform for rapid and sensitive miRNA-21 detection for heart failure diagnosis [0.03%]
一种便携式POCT平台 快速灵敏检测心力衰竭诊断用miRNA-21
Qian Kai Lin,Wen Qing Sun,Bo Zhang et al.
Qian Kai Lin et al.
Background: MicroRNAs (miRNAs) play a pivotal role in various physiological and pathological processes. In particular, miRNA-21 holds significant potential as a novel biomarker for the diagnosis of heart failure. The deve...
Development of aptamer-based monolithic sorbent in paper devices for lysozyme extraction in foods [0.03%]
基于适配体的纸基单片吸附剂的开发用于食品中溶菌酶的提取
Natalia Piqueras-García,Raúl Mínguez-Peláez,María Vergara-Barberán et al.
Natalia Piqueras-García et al.
Background: Lysozyme (Lyz) is a protein commonly used as a food preservative, but it can cause severe allergic reactions. Detecting trace amounts of Lyz in food is essential, requiring sensitive, reliable, and accessible ...
A novel electrocatalytic current dominated self-powered photoelectrochemical sensor based on patterned bipolar electrode [0.03%]
一种基于图案化双极电极的电流占优型自驱动光电化学传感器
Weiqiang Yang,Jingru Ke,Ziwang Xiao et al.
Weiqiang Yang et al.
Background: Self-powered photoelectrochemical (sPEC) sensors display significant potential in clinical diagnosis and health evaluation. Until now, most of sPEC sensors rely on individual or dual photoelectrodes systems, w...
Prediction of cross-linking properties in rubber-based materials by means of TD-NMR and chemometrics: data preprocessing, model building and chemical interpretation [0.03%]
基于TD-NMR和化学计量学预测橡胶材料交联性能：数据预处理、模型构建与化学解释
R Voccio,C Malegori,P Oliveri et al.
R Voccio et al.
Background: When dealing with vulcanized compounds for tyre and rubber industry, the determination of cross-linking density within the compound polymeric matrix is of a crucial importance. One of the most common methods u...
A "Turn-on" fluorescence sensing strategy based on DNA-templated silver nanoclusters for the detection of antibiotic resistance genes [0.03%]
一种基于DNA模板银纳米团簇的“开启”型荧光检测抗生素抗性基因的新方法
Jiaqian Li,Benzhi Wang,Jihui Peng et al.
Jiaqian Li et al.
Background: Antibiotic resistance genes (ARGs) are emerging environmental contaminants that pose serious threats to human health and ecological security due to their rapid migration and transformation in the environment. ...