Field-deployable RspCas13d platform for rapid and extraction-free detection of giant panda- and canine-derived Canine Distemper virus [0.03%]
一种便携式的RspCas13d平台 实现对犬瘟病毒的快速无提取检测
Qian Tao,Yuxiao Xing,Haidi Yang et al.
Qian Tao et al.
Background: Canine distemper virus (CDV) is a highly contagious RNA virus that causes severe disease in domestic dogs and diverse wildlife species, including endangered giant pandas. Current CDV diagnosis mainly relies on...
A 3D correlation spectroscopy framework for spectral feature decoupling: Enabling precise authentication and quantification of dairy cream fat adulteration [0.03%]
一种用于光谱特征解耦的三维相关光谱框架：实现乳稀奶油脂掺假的精准鉴别与定量分析
Xijun Wu,Xuan Zheng,Shixin Wang et al.
Xijun Wu et al.
Background: Traditional Raman spectroscopy for dairy cream fat (DCF) authentication is often severely compromised by temperature perturbations, which alter crystalline orderliness and obscure low-concentration adulteratio...
High-throughput UHPLC-MS/MS analysis of Cystatin C proteoforms and creatinine in human sweat for kidney function monitoring [0.03%]
人汗中半胱氨酸和肌酐的高通量UHPLC-MS/MS分析用于肾功能监测
Silvia Ghimenti,Alessio Lenzi,Mariano De Cristofaro et al.
Silvia Ghimenti et al.
Chronic kidney disease (CKD) is a major global health concern, requiring timely and accurate assessment of kidney function for effective patient management. Creatinine and Cystatin-C (CysC) are well-established biomarkers for estimating glo...
Molecular engineering of a D-A-D-type fluorescent probe for detecting viscosity in environmental and living systems [0.03%]
用于检测环境和活体系统粘度的D-A-D型荧光探针的分子工程学研究
Jing Shu,Hao-Long Sun,Xu-Bo Fan et al.
Jing Shu et al.
Background: Organellar viscosity is an important biomechanical parameter and is closely associated with multiple physiological and pathological processes. Push-pull molecular rotors can realize viscosity visualization via...
A review on deep eutectic solvent-functionalized paper analytical platforms [0.03%]
基于深共熔溶剂的纸基分析技术研究进展
Andrey Shishov,Lawrence Nugbienyo,Ekaterina Davidova et al.
Andrey Shishov et al.
Paper-based analytical devices constitute one of several complementary approaches to enabling portable, decentralized chemical analysis. Despite their low cost, simplicity, and compatibility with on-site testing, their analytical performanc...
Triple quenching strategy-based highly sensitive electrochemiluminescence sensor for perfluorooctanoic acid [0.03%]
基于三淬灭策略的高性能电化学发光传感器检测全氟辛酸
Ding Jiang,Bingxue Fan,Xue Wang et al.
Ding Jiang et al.
Quenching-based electrochemiluminescence (ECL) sensing boasts prominent advantages for trace analysis, while single-mechanism systems have inherent flaws, making the development of efficient synergistic quenching strategies of great practic...
Passive sampling for PFAS in a drinking water treatment plant: Potential utility, challenges, and pathways forward [0.03%]
饮用水处理厂中PFAS的被动采样：潜在效用、挑战及前进道路
Hyun-Ah Kwon,Min Jung Jeon,Yongju Choi
Hyun-Ah Kwon
Background: Per- and polyfluoroalkyl substances (PFAS) need to be effectively monitored in drinking water treatment plants (DWTPs) to assess treatment performance and manage potential health risks. Grab sampling provides ...
Density functional theory-assisted: In-situ growth of NH2-UiO-66 on polypyrrole for high-selectivity electrochemical detection of nitrophenol isomers [0.03%]
基于密度泛函理论的原位生长NH2-UiO-66@聚吡咯复合材料高效高选择性电化学检测硝基酚异构体传感器
Xuemei Wang,Rao Peng,Lin Fan et al.
Xuemei Wang et al.
Nitrophenol pollutants are ubiquitously distributed in the environment, however, it is very difficult to simultaneously detect its isomers. In this study, a new electrochemical sensor based on polypyrrole-modified amino-functionalized metal...
A dual-state emission NIR fluorescent sensor for intelligent dual-analyte detection and multisite imaging: From N2H4/ClO- and fingerprints to living cells and organisms [0.03%]
一种用于智能双分析物检测和多点成像的双态发射近红外荧光传感器：从N2H4/ClO-和指纹到活细胞和生物体
Su-Qian Cai,Bo-Wen An,Rui-Yong Jiang et al.
Su-Qian Cai et al.
Background: Hydrazine and hypochlorite as two important chemical reagents in reducing and oxidizing reactions are widely used in chemical industry, agriculture, environment and daily life. Therefore, it is essential to de...
Esterase fluorescent probe for precise diagnosis of diabetes and dynamic monitoring of insulin therapy [0.03%]
用于糖尿病精准诊断及胰岛素治疗动态监测的酯酶荧光探针
Shuai Fan,Shizhong Cui,Junying Du et al.
Shuai Fan et al.
Background: A hallmark of diabetes is persistent hyperglycemia, a condition highly prone to inducing oxidative stress and triggering multi-organ damage. As the central hub for glucose and lipid metabolism, the liver is pa...