High-performance liquid chromatography enables purification of red-emitting carbon dots for cellular imaging [0.03%]
高效液相色谱法用于红色发光碳点的纯化及细胞成像
Manivannan Madhu,Sih-Ying Chen,Po-Chiao Lin et al.
Manivannan Madhu et al.
Background: The hydrothermal method is widely employed for the synthesis of carbon dots (CDs); however, the resulting products often contain complex compositions, leading to inaccurate morphological and photophysical char...
Post-esterification preparation of carboxyl groups enriched magnetic microporous organic network for the efficient enrichment and determination of quaternary ammonium alkaloids [0.03%]
用于季铵生物碱的高效 enrichment 和测定的羧基富集磁性微孔有机网络的酯化后合成
Jian-Ming Liu,Jian Liu,Tian-Tian Ma et al.
Jian-Ming Liu et al.
Background: Microporous organic networks (MONs) are an emerging class of porous materials characterized by extremely large surface area, tunable topology, and superior stabilities, which have received increasing attention...
CuAg NCs with AIE Effect Coordinated by Ce3+ as a Novel Fluorescent Probe for the screening of ATP inhibiting drugs [0.03%]
一种新型荧光探针用于筛选ATP抑制剂：Ce~(3+)配位的具有AIE效应的CuAg纳米簇
Jinwen Chen,Huixiao Tong,Yuqing Wang et al.
Jinwen Chen et al.
Background: In recent years, bimetallic nanoclusters (NCs) have emerged as promising functional materials, particularly those exhibiting aggregation-induced emission (AIE) properties. Compared to single-metal systems or o...
Nicking-controlled biosensor: Integrating DNA Walker-RCA circuit with trimetallic nanozyme for aflatoxin B1 detection [0.03%]
基于DNA行者-滚环扩增的串联逻辑门控纳米酶生物传感器用于黄曲霉毒素B1检测
Longsheng Jin,YuJing Liu,Wenqing Xia et al.
Longsheng Jin et al.
Background: Aflatoxin B1 (AFB1) is a highly toxic mycotoxin that poses serious threats to global food safety and public health. The ingestion of these contaminated products causes substantial risks to both food safety sys...
A near-infrared ratiometric fluorescent probe for visual sensing of H2S and monitoring its fluctuation in plant roots under drought and flooding stresses [0.03%]
一种近红外比值荧光探针用于可视化检测H₂S以及监测干旱和洪涝胁迫下植物根部H₂S波动状况
Ruxuan Mo,Chao Kang,Jianping Yuan et al.
Ruxuan Mo et al.
Background: Hydrogen sulfide (H2S) is a key endogenous gasotransmitter involved in plant physiological regulation and stress responses. Monitoring its dynamic changes in plants is essential for understanding related signa...
Imaging mammalian lipids using desorption electrospray ionization mass spectrometry: A review [0.03%]
基于脱解电喷雾电离质谱的哺乳动物脂质成像：综述
Reham Abu Ghoush,Fakhri Geday,Oz Alon et al.
Reham Abu Ghoush et al.
Desorption electrospray ionization mass spectrometry imaging (DESI-MSI) has become an essential tool for spatial lipidomic profiling since its introduction in 2005. It provides key insights into the roles of lipids in cellular function, dis...
Detailed impurity profiling of graphene oxide fractions by robust inductively coupled plasma optical emission spectrometry monitoring [0.03%]
用于石墨烯氧化物分级的鲁棒耦合等离子体光学发射光谱监测的详细杂质分析
Iuliia A Poimenova,Elizaveta Yu Zhukova,Svetlana T Ovseenko et al.
Iuliia A Poimenova et al.
Background: Graphene oxide (GO) is widely used in biomedicine and biotechnology due to its aqueous dispersibility and potential nanozyme activity. However, it remains analytically challenging because of structural heterog...
Establishment of a rapid colorimetric sensor for Microcystin-LR based on specific aptamer and positively charged gold nanoparticles [0.03%]
基于特异性适配体和带正电荷的金纳米粒子的微囊藻毒素-LR快速比色传感器的建立
Xueting Cui,Jun Wang,Tingyu Hou et al.
Xueting Cui et al.
Eutrophication of surface freshwater drinking sources intensifies, leading blue-green algae to release massive microcystins. Microcystin-LR (MC-LR), the most toxic variant, poses severe threats to public health and environmental safety. Con...
Histology-guided spatial lipidomics and proteomics of the trisynaptic circuit in the human hippocampus [0.03%]
基于组织学的人类海马三突触回路的空间脂质组学和蛋白质组学
Caitlin M Tressler,Lauren DeVine,Rahul Bharadwaj et al.
Caitlin M Tressler et al.
The human hippocampal trisynaptic circuit activity is essential for learning and memory. This canonical circuit has spatially distinct populations of neurons, but their unique contributions to neurodevelopment, as well as to dysfunction in ...
Amplification-free one-pot RNA detection by pairing CRISPR-Cas13a with cascade amplification circuit-driven DNAzyme (RAPID) [0.03%]
基于级联通敏电路的CRISPR-Cas13a一锅式RNA检测新技术
Xiaona Yin,Ziyan Zhang,Hao Luo et al.
Xiaona Yin et al.
RNA has become a versatile target for diagnosing a wide range of pathogens. The demand for rapid and accurate diagnostics in point-of-care (POC) or resource-limited settings is growing. However, most RNA-based assays depend on reverse trans...