Integrating DNA tetrahedron with affinity magnetic levitation for selective capture and sensitive detection of circulating tumor cells [0.03%]
集成了DNA四面体的亲和磁力悬浮技术在循环肿瘤细胞捕获与检测中的应用研究
Zilong Zhang,Sidi Cun,Yuxuan Yuan et al.
Zilong Zhang et al.
Circulating tumor cell (CTC) is an evidenced biomarker for early cancer diagnosis and assessment of treatment response. This necessitates increasing attempt to develop new method for detection of CTCs with highly enriching and anti-interfer...
Highly amphiphilicity-tailorable pineapple-like janus nanozymes with superior kinematic locomotion facilitates biphasic chemiluminescence analysis [0.03%]
高度两亲性可调的菠萝状 Janus 纳米酶具有优异的动力学运动能力，有利于双相化学发光分析
Xin Jiang,Wan Wei,Yueming Zhao et al.
Xin Jiang et al.
Background: Due to ideal stability, ease of preparation and high cost efficiency, nanozymes have been adopted as the substitutes of natural enzymes in homogeneous catalysis. However, the application of nanozymes was restr...
Fe-Mo atomic-scale synergy enables trace detection and multidimensional fingerprinting of phenolic pollutants [0.03%]
费-钼原子尺度协同作用实现痕量酚类污染物的检测及多维度指纹识别
Yizeng Mu,Xixian Zhu,Xuebo Liu et al.
Yizeng Mu et al.
Phenolic pollutants, originating from petrochemical production, dyeing and domestic wastewater, are among the most persistent and toxic organic contaminants in aquatic systems. Their structural diversity and similar physicochemical properti...
Oxygen vacancy-modified MnCo2O4 nanoneedles grown on a nickel-titanium fiber support for boosting solid-phase microextraction of trace ultraviolet filters from water [0.03%]
氧空位修饰的MnCo₂O₄纳米针阵列生长在镍钛丝上，用于水相中紫外吸收剂固相微萃取检测性能研究
Leilei Chang,Nian Qin,Yuyun Wang et al.
Leilei Chang et al.
Background: Ultraviolet filters (UVFs) are widely used in personal care products to protect human skin from UV radiation in sunlight. The accumulation of these synthetic chemicals in environmental water may pose potential...
Microscale hemoglobin assay for time-resolved kinetic analysis of nitric oxide release from electrospun hydrogels [0.03%]
微尺度血红蛋白测定法，用于电纺水凝胶释放一氧化氮的时间resolved动力学分析
Carolina Gutierrez Cisneros,David Polania Melo,Veerle Bloemen et al.
Carolina Gutierrez Cisneros et al.
Background: Nitric oxide (NO) delivery from diazeniumdiolate donors is widely explored in biomaterial design for wound healing and regenerative medicine. However, accurate quantification of NO release remains challenging ...
Xiaorong Song,Mingyang Li,Wenya Chang et al.
Xiaorong Song et al.
Background: Exosomes (EXOs) are promising biomarker sources for liquid biopsy. Due to their low abundance in biofluids and the presence of non-target vesicle proteins during the isolation process, traditional methods such...
Diagnostic and therapeutic intelligent probe: Photoacoustic/ fluorescent dual-modality of thiols detection in tumor and ROS-potentiated cancer photodynamic therapy [0.03%]
一种用于肿瘤治疗和诊断的智能探针：含硫基分子的光声/荧光双模式检测及活性氧增强型癌症光动力疗法
Xiaoyan Su,Ruifeng Zeng,Hongyu Li et al.
Xiaoyan Su et al.
Diagnostic integration technology represents a significant advancement in cancer diagnosis and treatment. The combination of fluorescence probe-based imaging methods with photodynamic therapy (PDT) offers distinct advantages due to its high...
Performance enhancement of CRISPR-Cas system based on improved guide RNA: a review [0.03%]
基于改进的向导RNA的CRISPR-Cas系统性能增强研究进展综述
Xiaozhuang Zhang,Chenyan Tian,Min Wang et al.
Xiaozhuang Zhang et al.
Background: CRISPR-Cas technology has emerged as a transformative tool with widespread applications in gene editing and biosensing research; nevertheless, it is plagued by a suite of performance-related bottlenecks, inclu...
Mechanistic insights into persulfate-driven electrochemiluminescence amplification enabled by a Ru@Cu-MOGs/Zr-CeO2-Ag hybrid system [0.03%]
Ru@Cu-MOGs/Zr-CeO2-Ag杂化体系驱动过硫酸盐增强的机理视角电致化学发光放大反应
Wenwen Jiang,Haoyi Ren,Wenjing Lai et al.
Wenwen Jiang et al.
Electrochemiluminescence (ECL) is well suited for ultrasensitive bioanalysis; however, persulfate-based ECL systems often suffer from inefficient electron transfer and unstable reactive intermediates, which restrict signal amplification. He...
A label-free magnetic bead affinity approach for direct target identification of herbal extract: Ganoderma lucidum as a case [0.03%]
一种针对草药提取物的直接目标鉴定方法：以灵芝为例的无标记磁珠亲和方法
Han Li,Bo Peng,Bo Li et al.
Han Li et al.
Ganoderma lucidum (Chinese name: Lingzhi) has been used for the treatment of diverse liver disorders for centuries in traditional Chinese medicinal practices. Ganoderic acids (GAs) have been well-established as the key bioactive constituent...