Dye displacement on a GO-like cationic porphyrin polymer for heparin sensing and quality control [0.03%]
用于肝素检测和质量控制的类石墨烯阳离子卟啉聚合物染料置换法
Yusheng Fan,Yanlin Fu,Chunfei Bao et al.
Yusheng Fan et al.
Background: It is meaningful but challenging to develop convenient and accurate analytical methods for heparin sensing, owing to its complex and heterogeneous chemical structure. Although indicator displacement assay offe...
Highly sensitive H2O2 colorimetric sensing in tumor cells via stable phospholipid-coated CsCu2I3 peroxidase-like nanoenzyme [0.03%]
一种稳定的磷脂涂层CsCu2I3类过氧化物酶纳米酶用于肿瘤细胞中H2O2的高灵敏比色检测
Jiatong Wang,Yang Yu,Yawen Fan et al.
Jiatong Wang et al.
Background: Highly sensitive and rapid detection of hydrogen peroxide (H2O2) associated with tumor cells is potentially valuable for cancer-related bioanalysis and therapeutic evaluation. However, it remains challenging t...
A paper-based sensor with distance readout for rapid on-site screening of promethazine hydrochloride in beverages [0.03%]
一种用于现场快速筛查饮料中盐酸普马嗪的纸基传感检测装置
Jia Xu,Xiaofei Zhang,Shuang Lin et al.
Jia Xu et al.
Background: The recreational abuse of promethazine hydrochloride, particularly when mixed with soft drinks, has raised significant public concern. Although well-established chromatographic methods are available for the an...
Single-probe Pd-modified ZnO-polymer fluorescent sensor array for discrimination of thymidine analogues in aqueous media [0.03%]
用于水相中胸腺嘧啶类似物识别的单探针Pd修饰ZnO-聚合物荧光传感器数组
Kostubh Gaur,Ranbir,Navneet Kaur et al.
Kostubh Gaur et al.
Thymidine analogues are widely used as antiviral and anticancer agents; however, improper dosage and prolonged exposure can lead to severe hematological and genetic complications, necessitating reliable methods for their detection and discr...
Highly sensitive m6A electrochemical biosensor based on laser-induced graphene electrodes functionalized with DNA tetrahedron/gold-antibody nanoparticle [0.03%]
基于激光诱导石墨烯电极的DNA四面体/金抗体纳米颗粒修饰的高灵敏m6A电化学生物传感器
Huiyan Cao,Xi Cheng,Li Huang et al.
Huiyan Cao et al.
Background: N6-methyladenosine (m6A), the most abundant internal modification of eukaryotic mRNA, post-transcriptionally regulates gene expression, and its dysregulation is intimately linked to tumorigenesis and multiple ...
Microfluidic Dean-flow enhanced electrochemical detection of lead in water [0.03%]
微流体Dean流强化电化学水溶液铅检测法
Shapour Jafargholinejad,Basit Ilyas,Stephanie Gora et al.
Shapour Jafargholinejad et al.
Background: We present a cost-effective microfluidic electrochemical sensor (MES) that operates without electrode surface modification, utilizing curved microchannels to promote efficient analyte transport and enhance ele...
Deep quantitative proteomic analysis of gingival crevicular fluid for severe pediatric caries [0.03%]
儿童严重龋齿的牙龈分泌物定量蛋白质组分析
Xue Yang,Ting Zhao,Pingbo Yu et al.
Xue Yang et al.
Background: Mass spectrometry (MS)-based proteomics approaches have proven to be a powerful tool to discover clinical biomarkers for dental caries diagnosis and management. Saliva, acquired enamel pellicle (AEP), and dent...
A novel AgNPs spongy trap coupled with portable XRF: a field-ready strategy for sensitive mercury analysis in soils [0.03%]
一种新型的AgNP海绵结合便携式XRF：土壤中汞现场灵敏检测策略
Lin Li,Yan Xu,Guanyu Lan et al.
Lin Li et al.
Background: Rapid and sensitive on-site detection of mercury in soil is crucial for environmental monitoring, however, current methods generally involve lengthy and complex sample digestion procedures thereby hindering tr...
Cosmic spike removal based on multi-feature fusion for long-time integrated Raman spectral detection [0.03%]
基于多特征融合的拉曼光谱长时间积分宇宙噪声消除方法
Huijie Wang,Xu Liu,Xujin Hu et al.
Huijie Wang et al.
Background: Raman spectral detection is commonly performed with a relatively long integration time to suppress the dominant interference of random detecting noise for better signal-to-noise ratio, while inevitably increas...
Sandwich-type complex-activated DNA circuit for highly sensitive and versatile detection of protein biomarkers for monitoring bone health [0.03%]
一种用于骨健康监测的蛋白质生物标志物的高度灵敏且多功能检测的夹心型复杂激活的DNA电路
Wenming Pan,Zhan Zhang,Quanshan Jin et al.
Wenming Pan et al.
Background: In recent years, aptamer-based biosensing methods have achieved notable advances in the detection of protein biomarkers associated with various diseases. Despite this progress, their clinical utility remains c...