High-throughput simultaneous quantification of glycopeptides and phosphopeptides enabled by 12-plex DiLeu isobaric tags and dual-functional Titanium(IV)-IMAC material [0.03%]
基于DiLeu等压标签和双功能Ti(IV)-IMAC材料的高通量糖肽与磷酸肽的同时定量分析方法
Feixuan Wu,Danqing Wang,Dylan Nicholas Tabang et al.
Feixuan Wu et al.
Background: Protein glycosylation and phosphorylation are critical post-translational modifications (PTMs) that regulate diverse physiological and pathological processes, yet their comprehensive characterization remains c...
Nanozyme fabrication based on magnetic COFs and gold nanorods and its SERS detection of zearalenone [0.03%]
基于磁性COF和金纳米棒的纳米酶的制备及其对玉米赤霉烯酮表面增强拉曼光谱检测研究
Xiaoyuan Ma,Xi Ma,Muxi Zhang et al.
Xiaoyuan Ma et al.
Background: As one of the most common mycotoxins, Zearalenone (ZEN) not only contaminates cereal crops but also exists in processed grain products for its chemical stability. After entering human body through the food cha...
An improved ion-exchange-to-silver-salt procedure for δ18O measurement of nitrate in natural samples [0.03%]
改进的离子交换-银盐法测定天然样品中硝酸盐氧同位素比率(δ18O)
Bo Wang,Chao Li,Ying Wang et al.
Bo Wang et al.
Background: The oxygen isotope composition (δ18O) of natural nitrate is a proven effective indicator of its sources and the (bio)geochemical processes that it has experienced. Removing interfering species (in particular ...
Ultrafast peptide preparation brings shotgun proteomics into the minute era [0.03%]
超快肽段制备使蛋白质组学进入分钟时代
Haowei Ma,Ming Bi,Lang Zhao et al.
Haowei Ma et al.
Background: Mass spectrometry-based shotgun proteomics relies on efficient sample preparation, where proteins are reduced, alkylated, and digested into peptides for LC-MS/MS analysis. While LC-MS/MS and bioinformatic iden...
Optical-fiber sensors for dissociation constant measurement of aptamer and rapid detection of ampicillin in river water and milk [0.03%]
一种新型光学纤维传感器及其在抗生素检测中的应用研究
Guangxin Zhang,Haixu Zhao,Xiaoqi Li et al.
Guangxin Zhang et al.
Background: The conflicted affinity evaluation results of small molecule-binding aptamers (SM-Apts) are increasing, raising the concerns on if a reported aptamer is a real aptamer. AMP17 is the first published controversi...
Insights on extracting mechanisms and interference factors of solid-phase extraction for trace sulfamethoxazole enrichment [0.03%]
固相萃取富集痕量磺胺甲恶唑的机制及干扰因素解析研究进展
Yongjie Li,Haichuan Zhang,Wenxin Huo et al.
Yongjie Li et al.
Sulfamethoxazole (SMX) has garnered global attention due to its presence in trace amounts (ng L-1 to μg L-1) in water bodies. Solid-phase extraction (SPE) is a key pretreatment step for analyzing trace SMX, and its efficiency significantly...
Measuring absolute gas amounts with gas chromatography by using a novel setup for pressure based gas control [0.03%]
基于压力的气体控制的新装置实现的气相色谱绝对气体量测定方法研究
Andreas Hofmann,Ingo Reuter,Freya Müller et al.
Andreas Hofmann et al.
The characteristics of the gas itself, such as its volatility, compressibility, or weight, often complicate the process of feeding gas into a measuring system, such as a gas chromatograph. This is particularly relevant when quantifying indi...
Microscale native size exclusion chromatography high resolution mass spectrometry for the determination of the chelator-to-antibody ratio of immunoconjugates [0.03%]
微尺度原生体积排阻色谱高分辨率质谱法测定免疫偶联物中螯合剂与抗体比率
Annika A M van der Zon,Bram Weijers,Danielle J Vugts et al.
Annika A M van der Zon et al.
Background: Positron emission tomography (PET) using radiolabeled antibodies (radioimmunoconjugates) is a powerful imaging technique to track the distribution of therapeutic antibodies. Accurate determination of the avera...
Development of dual-template molecularly imprinted polymers for the selective extraction of acetamiprid and thiamethoxam [0.03%]
双模板分子印迹聚合物的制备及其对乙霉威和噻虫meth奥胺的选择性提取研究
Saqib Farooq,Jie Zhang,Jia Xie et al.
Saqib Farooq et al.
This study presents a novel analytical method based on molecularly imprinted polymers (MIPs) synthesized using an eco-friendly β-CD-DES functional monomer. These MIPs were developed for the selective extraction of acetamiprid (ACT) and thi...
Cyclic ion mobility-mass spectrometry to enhance the separation of pyrrolizidine alkaloid epimers [0.03%]
用于提高吡咯里西啶生物碱差向异构体分离的循环离子淌度-质谱法
Laura Carbonell-Rozas,Nicola Dreolin,Chiara Dall&#x;Asta et al.
Laura Carbonell-Rozas et al.
Background: Cyclic ion mobility spectrometry (cIMS) has emerged as a powerful tool for enhancing the resolution of isomeric and epimeric species that remain unresolved by traditional LC-MS or single-pass ion mobility tech...