Preparation of metalloporphyrin-based porous organic polymer materials for extraction of bisphenol analogues from food extracts [0.03%]
基于金属多吡咯的多孔有机聚合物材料的制备及其在食品基质中双酚类物质 enrichment中的应用研究
Xiaoli Wei,Xuecheng Zhu,Qing Wei et al.
Xiaoli Wei et al.
Background: Bisphenol analogues (BPs) are recognized as endocrine disrupting chemicals (EDCs) that pose risks to human health. However, the accurate detection of BPs faces significant challenges due to their trace-level c...
Rapid detection of bloodstream infection bacteria directly from positive blood cultures by ultraviolet photoionization time-of-flight mass spectrometry [0.03%]
基于紫外光解离子化飞行时间质谱的血培养瓶阳性直接鉴定快速检测方法研究
Zhuoya Li,Quanfeng Liao,Yi Xie et al.
Zhuoya Li et al.
Background: Bloodstream infection (BSI) has a high incidence and mortality rate worldwide. Early diagnosis of pathogens is crucial for controlling disease progression and providing precise antibiotic treatment. Current cl...
MALDI matrix sublimation versus spray coating in the FluoMALDI imaging pipeline [0.03%]
基质升华与喷涂在FluoMALDI成像流程中的应用比较研究
Tae-Hun Hahm,Wanyue Wang,Dalton R Brown et al.
Tae-Hun Hahm et al.
Background: This study advances the FluoMALDI pipeline for tissue autofluorescence applications by integrating slide-scanning fluorescence microscopy (SSFM) with matrix-assisted laser desorption/ionization (MALDI) imaging...
Comparative Study
Analytica chimica acta. 2025 Nov 22:1376:344610. DOI:10.1016/j.aca.2025.344610 2025
Rapid and highly sensitive mass spectrometric detection of n-alkanes via a novel photoionization-induced nitrogen dioxide cation chemical ionization source [0.03%]
一种新型光离解氮氧化物阳离子化学电离源快速灵敏地检测正构烷烃
Baimao Zhang,Bo Li,Lei Hua et al.
Baimao Zhang et al.
Background: Soft ionization mass spectrometry is an excellent direct detection technique with advantages such as speed, simplicity, and ease of operation. Chemical ionization (CI) is a typical soft ionization method that ...
On-chip single-cell mass spectrometry for streamlined metabolic exploration enabled by a reversibly-bonded microfluidic platform [0.03%]
基于可逆键合微流控平台的片上单细胞质谱技术实现精简的代谢探测研究
Jiacheng You,Anqi Chen,Jianxiong Qiu et al.
Jiacheng You et al.
Background: Single-cell mass spectrometry (SCMS) deepens the insight into current bioanalytical science. Precise cell positioning is a critical step in SCMS workflow because it provides accurate spatial coordinates of the...
Enhancing in-situ molecular profiling of gastric cancer for spatial proteomics through optimized digestion [0.03%]
通过优化消化改善胃癌原位分子谱分析以进行空间蛋白质组学研究
Lydia Jung,Julius Shakhtour,Bianca Grosser et al.
Lydia Jung et al.
Background: Gastric cancer has a high incidence worldwide, affecting men more frequently than women. Treatment options remain limited in their success, primarily due to insufficient knowledge about the disease. The high d...
Identification of micro-/nanoplastics in human placental blood using comprehensive multidimensional pyrolysis - gas chromatography x ion mobility mass spectrometry [0.03%]
使用综合多维裂解-气相色谱x离子淌量质谱法识别人体胎盘血中的微/纳米塑料
Justine R Bissonnette,Nikita E Harvey,Mikela L Rowsell et al.
Justine R Bissonnette et al.
Background: Micro-/nanoplastics (MNPs) are ubiquitous environmental contaminants and there has been a growing concern about their potential adverse effects on human health. The present study reports on the development of ...
An aptamer-MIP dual-recognition electrochemical sensor utilizing Au-Pt bimetallic nanoflowers and CMCS@COF-300 nanocomposites for the ultrasensitive detection of aflatoxin B1 [0.03%]
利用Au-Pt纳米花朵和CMCS@COF-300纳米复合材料的适配体-MIP双识别电化学生物传感器用于黄曲霉毒素B1的超灵敏检测
Hai Chi,Yue Xiao,Xuefei Wen et al.
Hai Chi et al.
Background: Aflatoxin B1 (AFB1), as a Group 1 carcinogen designated by IARC, poses severe threats to global food safety due to its extreme toxicity and widespread contamination in crops like corn, peanuts, and cereals. Cu...
A neutral multivalent AIE-TICT scaffold: An off-on, wash-free fluorogenic strategy for biosensing glycan-protein interactions in live cells and mycobacteria [0.03%]
一种中性多价AIE-TICT支架：用于活细胞和结核分枝杆菌中糖蛋白相互作用的“开/关”、“无清洗”的荧光检测策略
Huai-En Chang,Chien-Chin Chen,Yi-Jin You et al.
Huai-En Chang et al.
Background: Fluorescent probes for wash-free imaging of weak or transient interactions, such as glycan-glycan-binding protein (GBP) recognition, remain limited by poor responsiveness and high background emission. A modula...
A pyridinemalononitrile-based polarity-responsive fluorescent probe for lipid droplet dynamics tracking and nonalcoholic fatty liver disease diagnosis [0.03%]
一种基于嘧啶-马来腈的响应介质极性的荧光探针用于脂滴动态示踪及非酒精性脂肪肝病诊断
Boyu Feng,Han Zhao,Yuan Cheng et al.
Boyu Feng et al.
Lipid droplets (LDs) are highly dynamic organelles that play crucial roles in various physiology processes, and their excessive accumulation is closely associated with nonalcoholic fatty liver disease (NAFLD). Therefore, the rational design...