A near-infrared fluorescent probe lights up protective carbon monoxide during inflammation in live systems [0.03%]
一种近红外荧光探针 可在活体系统中检测炎症过程中具有保护作用的一氧化碳
Sihang Lv,Longyang Yang,Changjian Wu et al.
Sihang Lv et al.
Background: The role of carbon monoxide (CO) as a fundamental gasotransmitter in cellular signaling and redox homeostasis is well-established. Precise in vivo tracking of CO remains a significant challenge, as most existi...
A portable platform for polyethylene microplastics quantification using an Arduino automatic system [0.03%]
一种用于聚乙烯微塑料定量的Arduino自动系统便携式平台
Shijing Yang,Yajing Sun,Yaming Yang et al.
Shijing Yang et al.
Background: The ubiquitous microplastics (MPs) are serious threaten to human health because of their tiny size, wide distribution and low degradation. Due to their stable physicochemical properties and low cost, plastics ...
A highly sensitive and simultaneous bifunctional fluorescent probe for detecting mitochondrial viscosity and nitroreductase activity in vivo [0.03%]
一种用于检测活细胞内线粒体粘度和硝基还原酶活性的高灵敏度双功能荧光探针
Manlin Fu,Jiarong Zhou,Qingwen Li et al.
Manlin Fu et al.
Background: Mitochondrial dysfunction and dysregulated enzymatic activity are hallmarks of liver cancer progression. Mitochondrial viscosity reports changes in the organelle microenvironment, whereas nitroreductase (NTR) ...
Engineering carbon dots with amplified peroxidase-mimetic activity for dual-modal colorimetric-photothermal sensing of organophosphorus and carbamate pesticides [0.03%]
工程化碳点具有增强的类过氧化物酶活性用于有机磷和氨基甲酸酯农药的双模彩色-光热检测
Na Gao,Yajuan Zhao,Yuhan Huang et al.
Na Gao et al.
Background: Although the widespread utilization of nanozyme-based sensing systems in the determination of pesticides, the rational design of carbon dots (CDs)-based nanozymes with superior catalytic activity for multimoda...
Non-destructive classification of type 2 diabetic teeth using LIBS-derived elemental biomarkers and machine learning [0.03%]
基于LIBS衍生的元素生物标志物和机器学习的2型糖尿病牙齿非破坏性分类
Muhammad Mustafa Dastageer,Khurram Siraj,Giorgio Saverio Senesi et al.
Muhammad Mustafa Dastageer et al.
Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic illness that severely alters oral health, elevating periodontal infection incidence and dental treatment failures via mechanisms including hyperglycemia. ...
CARES-Net: a channel-attention residual network for multi-disease classification in small-sample 1H NMR metabolomics data [0.03%]
基于通道注意力残差网络的低通量¹H核磁代谢数据多病种分类模型CARES-Net
Zihang Ye,Yucheng Guo,Zhicheng Ji et al.
Zihang Ye et al.
Background: NMR-based metabolomics is widely used in disease diagnosis due to its non-destructive and quantitative advantages. However, its analytical performance is often limited by the high-dimensional feature space der...
Sensitive detection of methylated DNA by elemental labeling inductively coupled plasma mass spectrometry using exponential amplification and DNAzyme [0.03%]
利用指数扩增和脱氧核糖酶的DNA甲基化敏感检测元素标记电感耦合等离子体质谱法
Shaocheng Liu,Beibei Chen,Man He et al.
Shaocheng Liu et al.
Background: A highly sensitive method for the quantification of methylated DNA was developed by integrating gold nanoparticles (AuNPs) labeling with inductively coupled plasma mass spectrometry (ICP-MS), coupled with the ...
Stereospecific recognition of S-fluoxetine enabled by HOF-101-based multimodal probe [0.03%]
基于HOF-101的多模式探针实现对S-氟西汀的立体选择性识别
Yiqi Chen,Yuxin Zhang,Fuyang Jiang et al.
Yiqi Chen et al.
Background: Given the distinct pharmacological activities and toxicological profiles of fluoxetine enantiomers, highly selective analytical tools are essential to ensure medication safety and advance the accuracy of chira...
Investigation of the CL-resin® properties for a sulfur-free content molecule protocol [0.03%]
关于无硫含量分子测定的CL树脂性能研究
Amayès Gaston-Bellegarde,Azza Habibi,Pascal Fichet
Amayès Gaston-Bellegarde
The accurate quantification of chlorine, and particularly of 36Cl, remains challenging due to severe spectral interferences and the incompatibility of conventional sulfur-based purification protocols with ICP-MS/MS analysis. In this study, ...
Magnetic-field-assisted extractive sample preparation of highly viscous crude oil for metal determination (Ni, V) by ICP [0.03%]
磁場輔助提取高粘度原油中的金屬(Ni和V)并用ICP法測定样品的前处理方法
Natalya S Musina,Yuliya N Romanova,Tatyana А Maryutina
Natalya S Musina
Background: The determination of metals in high-viscosity petroleum feedstocks remains analytically challenging due to strong matrix effects, high contents of resins and asphaltenes, and the presence of vanadium and nicke...