Spectrally resolved lithium isotope quantification through high-resolution spatial heterodyne spectrometry [0.03%]
高分辨率空间混频光谱法实现锂同位素的光谱分辨定量分析
Xunyu Li,Jens Riedel,Yi You
Xunyu Li
Isotope ratio determination of lithium is increasingly important in fields ranging from geochemistry to battery diagnostics. While mass spectrometry remains the gold standard, it is costly, cumbersome, and incompatible with portable or inli...
Fluorescent probe for simultaneous visualization of lipid peroxidation and lipid droplets accumulation in living cells [0.03%]
用于活细胞中同时可视化脂质过氧化和脂滴积累的荧光探针
Xinming Li,Yanan Hou,Fang Zhang et al.
Xinming Li et al.
Back ground: Lipid peroxidation (LPO) and abnormal accumulation of lipid droplets (LDs) are key pathogenic factors contributing to the onset and progression of multiple diseases. Fluorescent probes for monitoring LPO and ...
A novel N-alkyhydrazone-based Iridium(III) complex for luminescence imaging of mitochondrial hypochlorous acid in liver injury [0.03%]
一种新型N-烷基叠氨基杂环铱(III)配合物用于检测肝损伤中的次氯酸分布和定位闪烁成像
Lingtan Kong,Ling Wang,Shaozhen Jing et al.
Lingtan Kong et al.
The production of hypochlorous acid (HClO) is well recognized as a biomarker for liver injury, however, existing HClO bioimaging probes often lack specificity. Inspired by the specific recognition of oxime and hydrazide groups for HClO, we ...
An innovative method for simultaneous separation and determination of monosaccharide and sugar alcohol isomers associated with glycometabolism in beagle plasma using gas chromatography-mass spectrometry [0.03%]
一种用于同时分离和测定与糖代谢相关单糖和糖醇异构体的新方法：气相色谱-质谱法测定比格犬血浆中的单糖和糖醇异构体
Haihui Ren,Wen Xiao,Jiameng Han et al.
Haihui Ren et al.
Background: Tracking changes in plasma concentrations of monosaccharides and sugar alcohols related to glycometabolism, which plays a role as the main source of energy, is of great significance for the treatment of metabo...
MOF-on-MOF nanomaterial (Fe-MOF@UiO-66)-based ratiometric fluorescence/colorimetric dual-mode sensor for ultrasensitive detection of uric acid [0.03%]
一种超灵敏检测尿酸的新型MOF基比值型荧光/比色双模传感材料(Fe-MOF@UiO-66)
Tao Lian,Rui Peng,Zhengyue Xiao et al.
Tao Lian et al.
Background: Uric acid (UA) is a key metabolite of purine metabolism, and its elevated concentration in the blood is closely associated with various health conditions, particularly gout. It is of great significance to deve...
Separation and analysis of proteins by capillary electromigration methods in the period mid-2021-2024 [0.03%]
2021年中至2024年间基于毛细管电迁移学的蛋白质分离与分析技术
Sille Štěpánová,Václav Kašička
Sille Štěpánová
This review article presents an overview of the recent significant developments in the separation and analysis of intact proteins by capillary electromigration methods published in the period mid-2021-end-2024. The topics reported include s...
A novel analytical method for precise monitoring of biodiesel water content and stability [0.03%]
一种精确监测生物柴油含水量和稳定性的新型分析方法
Mohammadreza Asghari,Tao Wang,Li Zhu et al.
Mohammadreza Asghari et al.
Biodiesel is highly reactive with water, posing significant challenges to its commercialization. Therefore, accurate and safe monitoring of biodiesel is essential to prevent unwanted reactions. A U-shaped optical fiber (UOFE) was developed ...
Synthesis of a novel COF and its composite with PPY during cyclic voltammetric electropolymerization to prepare a new thin film microextraction device [0.03%]
一种新型共价键连接聚合物的合成及其与PPY复合电聚合过程中的环伏安法用于制备新的薄膜微萃取装置
Kobra Khodarahmian,Abdullah Barkhordari,Paul R Haddad et al.
Kobra Khodarahmian et al.
Background: Covalent organic frameworks (COFs) are new promising materials for separation purposes due to their high porosity, significant thermal and chemical stability, and tunable structures. Conductive polymers, such ...
Tryptic peptide mapping on antibody-drug conjugates: Improvements in hydrophobic peptide recovery and missed cleavages [0.03%]
抗体偶联药物的胰蛋白酶肽图：疏水性肽回收率改进和漏切位点分析
Xiao Pan,Yimeng Zhao,Zhijie Wu et al.
Xiao Pan et al.
Background: Antibody-drug conjugates (ADCs) have become a promising treatment for various cancers, by combining the specificity of monoclonal antibodies (mAbs) with the potent cytotoxicity of small-molecule drugs. The int...
Accelerating biotherapeutics discovery: Blueprint for a universal LC-MALDI-MS offline approach [0.03%]
加速生物疗法的发现：通用LC-MALDI-MS离线方法的蓝图
Elizabeth F Bayne,Xiong-Zhuo Gao,Yuan Jiang et al.
Elizabeth F Bayne et al.
Background: Biotherapeutics are a prominent class of molecules used to treat a wide range of diseases, including cancer, infections, inflammatory and immune disorders. The discovery workflow involves high-throughput scree...