Optimised ligand exchange solvent extraction methodology for the determination of labile and inert forms of copper in environmental samples [0.03%]
最优化配体交换溶剂萃取法测定环境样品中铜的易变和惰性形态的方法
Narda Stipanović,Dora Crmarić,Marina Mlakar et al.
Narda Stipanović et al.
A recent study using a competitive ligand exchange solvent extraction (CLE-SE) method indicates that oceanic copper (Cu) exists in two distinct pools: a labile fraction dominating surface waters, likely produced by photochemical degradation...
In-line spectroscopic measurement of pH profiles using methyl orange: Application to pH transients in protein A chromatography [0.03%]
甲基橙用于pH梯度条件下溶液pH值的在线光谱测定及蛋白质A层析过程中的应用
Angela R Moser,R Helen Zha,Steven M Cramer
Angela R Moser
In this work, we developed a method using the pH indicator methyl orange and an in-line UV detector to obtain accurate pH profiles for chromatographic applications in the pH range from 3.2-4.5. A linear calibration was used for conversion o...
Stereoselective neuroprotective activity and blood-brain barrier permeability of Schisandrin B enantiomers [0.03%]
五味子素B对映体的 stereo selective神经保护活性及其通过血脑屏障的能力
Xuhua Qi,Zengbo Fang,Siqi Li et al.
Xuhua Qi et al.
Schisandrin B (Sch B), a major dibenzocyclooctadiene lignan from Schisandra chinensis, possesses a unique form of axial chirality and exhibits significant neuropharmacological properties. To address the formidable analytical challenge of re...
Step-growth grafted anion exchangers with hyperbranched polyglycerol modification for ion chromatography [0.03%]
带有超支化聚甘油修饰的逐步增长接枝阴离子交换剂用于离子色谱法
Kai Zhang,Chaoyan Lou,Qianwen Diao et al.
Kai Zhang et al.
Herein, we report a step-growth approach to constructing polyelectrolyte-grafted stationary phases for ion chromatography (IC). Linear polyelectrolytes were covalently immobilized onto diol-functionalized substrate particles via cycled di-e...
MMIP-assisted selective molecular depletion of icaritin-type aglycones for causality-guided metabolite identification in fermented Epimedium [0.03%]
基于因果关系导向代谢组的 MMIP 协助异黄酮类苷元的选择性分子去污方法——以淫羊藿发酵体系中主要成分的药效物质研究为例
Xinhua Li,Boyu Hao,Xiao Wang et al.
Xinhua Li et al.
Establishing causal relationships between individual metabolites and biological activity in complex natural product systems remains a significant analytical challenge, as conventional chromatographic profiling is largely limited to correlat...
Workflow for characterizing volatile oxidation compounds in walnut oil by headspace solid-phase microextraction comprehensive two-dimensional gas chromatography time of flight mass spectrometry coupled with tile-based Fisher ratio analysis and other chemometric tools [0.03%]
基于费希尔比值和化学计量学方法的核桃油挥发性氧化产物HS-SPME-GCxGC-TOFMS分析流程
Cassandra M Padilla,Robert E Synovec
Cassandra M Padilla
Due to their high fat content, it is well known that walnuts are highly susceptible to oxidation and thermal degradation. These processes produce various compounds, including aromatics, aldehydes, acids, ketones, and alcohols, resulting in ...
Construction of hierarchically porous ZnO@ZIF-8 for enrichment and sensitive detection of bisphenols in environmental matrices [0.03%]
分层次多孔ZnO@ZIF-8的构建在环境基质中富集和灵敏检测双酚类化合物中的应用
Zhenzhen Liu,Dan Li,Mengyuan Ren et al.
Zhenzhen Liu et al.
Due to their environmental durability and potential for bioaccumulation, bisphenol compounds result in serious threats to biological systems and human well-being, necessitating the development of extremely effective analytical techniques fo...
A synchronous counter-positive strategy via online CE-SELEX for high-efficiency aptamer selection [0.03%]
基于在线CE-SELEX的同步计数-阳性策略高效筛选适配体
Yi Zhao,Linsen Li,Liping Zhao et al.
Yi Zhao et al.
Capillary electrophoresis-based systematic evolution of ligands by exponential enrichment (CE-SELEX) has been widely recognized as an effective method for aptamer selection. In this study, we developed a CE-SELEX strategy to synchronize the...
A dividing-plane interpretation of thermodynamic void volume in reversed-phase liquid chromatography from PS-DVB and C8/C18 comparisons [0.03%]
聚苯乙烯-二乙烯基苯和C8/C18色谱柱反相液相色谱的热力学空体积的划分平面解释
Hung-Wei Tsui,Yi-Jyun Huang,Jie-Bi Hu et al.
Hung-Wei Tsui et al.
Accurate adsorption isotherms in liquid chromatography require an operational definition of the mobile-stationary phase boundary, which is commonly embedded in the hold-up (void) volume. In the minor-disturbance method (MDM), the correspond...
Dynamic model-based control for process variations in ion-exchange chromatography [0.03%]
基于模型的动态控制在离子交换色谱过程变异中的应用
Ruo-Que Mao,Yu-Cheng Chen,Yu-Xin Liao et al.
Ruo-Que Mao et al.
The capability of smart manufacturing to enable predictive and autonomous decision-making under uncertainty is highly valuable to ion-exchange chromatography (IEC), a critical purification step that is sensitive to variations in sample comp...