Phage display-derived single-chain variable fragment antibody for highly sensitive and specific detection of thiamethoxam residues in food matrices [0.03%]
一种用于高效特异性检测食品基质中噻虫嗪残留的噬菌体展示衍生单链抗体片段
Jiadi Sun,Yan Lai,Wancheng Ma et al.
Jiadi Sun et al.
Thiamethoxam (TMX), as a widely used pesticide, poses potential risks to food safety due to residual contamination, underscoring the need for highly sensitive recognition elements for its detection. This study constructed a phage-displayed ...
Production of monoclonal antibody against albendazole and its metabolites with homogeneous cross-reactivity and its application in lateral flow immunoassay [0.03%]
均一交叉反应性 albendazole �单克隆抗体的制备及其在胶体金试纸条中的应用研究
Dongfang Guo,Xinyu Zhang,Zizhe Li et al.
Dongfang Guo et al.
To avoid false-negative or false-positive results in immunoassays caused by non-uniform antibody cross-reactivity during the detection of the sum of albendazole sulfoxide (ABZSO), albendazole sulfone (ABZSO2), and albendazole-2-aminosulfone...
Anti-immune complex recognition elements in small-molecule analysis: Preparation, applications, and mechanisms [0.03%]
用于小分子分析的抗免疫复合物识别元件：制备、应用及机制研究
Jialin Zhang,Shumei Zheng,Xuefeng Xia et al.
Jialin Zhang et al.
The determination of small-molecule compounds (SMCs), including veterinary drugs, pesticides, and mycotoxins, in food and environmental matrices remains a critical challenge in analytical chemistry, often demanding detection methods with hi...
Flower honey matrix for in situ deep eutectic solvent formation and microextraction: liquid chromatographic determination of sulfonamides after derivatization [0.03%]
花粉基蜂蜜矩阵原位生成深共晶溶剂并进行微萃取的液相色谱测定衍生化磺胺类药物
Yaroslav Kurashov,Aleksei Pochivalov,Iurii Lodianov et al.
Yaroslav Kurashov et al.
The honey matrix contains sugars and water, which can act as components for the in situ formation of a hydrophilic deep eutectic solvent (DES). This enables liquid-phase microextraction into polar solvents without dilution of the sample, ow...
Orthogonal Cas13a/Cas12a cascade for one-pot amplification-free detection of miRNA-21 [0.03%]
用于一锅放大自由检测miRNA-21的正交Cas13a / Cas12a级联反应
Jing Yuan,Meng Shen,Lihua Ding et al.
Jing Yuan et al.
MicroRNAs (miRNAs) are promising biomarkers for clinical diagnosis and disease monitoring. However, current CRISPR/Cas-based miRNA sensors generally require reverse transcription or nucleic acid amplification to improve sensitivity, which c...
A Cu/ZIF-8-based flexible sensor for real-time monitoring of protocatechuic acid in plants under environmental stress [0.03%]
一种基于Cu/ZIF-8的柔性传感器 用于监测植物在环境压力下的原儿茶酸
Shengyan Liu,Congyi Zhao,Yuqi Fan et al.
Shengyan Liu et al.
Understanding the dynamic regulation of endogenous metabolites in plants under environmental stress is essential for elucidating plant adaptive mechanisms and improving crop resilience. However, conventional analytical methods are typically...
Progresses in viral detection technologies for wastewater-based epidemiology [0.03%]
废水流行病学病毒检测技术研究进展
Yuki Tanaka,Nur Asinah Binte Mohamed Salleh,Sian Yang Ow et al.
Yuki Tanaka et al.
Wastewater-based epidemiology (WBE) has emerged as a powerful surveillance tool used to assess public health by tracking infectious materials shed into sewage systems by infected hosts. To enable a widespread implementation of WBE, advanced...
A viscosity-responsive benzoindole probe targeting the endoplasmic reticulum for applications in cells and tissues [0.03%]
一种粘度响应的苯并吲哚探针用于靶向内质网及细胞和组织中的相关应用
Xuan Liu,Wen-Pei Ni,Xu Xu et al.
Xuan Liu et al.
Real-time monitoring of dynamic changes in endoplasmic reticulum (ER) viscosity is of paramount importance for elucidating the molecular mechanisms underlying various pathological processes, including autophagy and ferroptosis. To address t...
Mannose-engineered Eu-MOF for ratiometric fluorescent/colorimetric dual-detection and inhibition of E. coli [0.03%]
甘露糖工程欧氏金属有机框架比值荧光/比色检测和抑制大肠杆菌
Weiqi Wu,Zhen Wu,Sihang Yuan et al.
Weiqi Wu et al.
Reliable detection and fast inhibition of Escherichia coli (E. coli) are critical for public health and food safety, so the detection-inhibition-integrated strategies become critical. Herein, a mannose-engineered 3,5-dicarboxyphenylboronic ...
Development and validation of HPLC-UV and HPLC-MS/MS methods for ML-210 quantification [0.03%]
ML-210的HPLC-UV和HPLC-MS/MS测定方法的建立及验证
Maxime Murphy,Louiza Mahrouche,Martin Jutras et al.
Maxime Murphy et al.
ML-210 is a GPX-4 inhibitor with potential therapeutic relevance in cancer therapies. However, no validated (bio)analytical methods for its quantification have been reported, limiting its pharmacokinetic and stability investigations. This s...