Nano-enabled fluorescent sensing platforms for on-site detection of pesticides in food [0.03%]
基于纳米技术的荧光传感平台用于食品中农药现场检测
Nanjun Wang,Lisheng Zhu,Ruiyun Zhou et al.
Nanjun Wang et al.
Pesticide residues in food matrices pose significant threats to global food safety. Conventional chromatographic methods, though highly reliable, are constrained by high costs, lengthy analysis times, and limited field deployability, restri...
An automated 1D 1H and 2D 1H-13C HSQC NMR platform for high-field (900 MHz) metabolite profiling of cerebrospinal fluid [0.03%]
一种高场（900MHz）脑脊液代谢轮廓分析的自动化的1D 1H和二维1H-13C HSQC核磁共振平台
Alexis Wuyart,Agathe Martinez,François-Xavier Cantrelle et al.
Alexis Wuyart et al.
NMR spectra from cerebrospinal fluid (CSF) samples (n = 25) were acquired using a high-field spectrometer at 900 MHz. The digital platform BioMetIQ was developed for 1D 1H and 2D 1H-13C HSQC experiments to characterize the metabolome in bio...
Sweat lactate threshold heart rate monitoring based on multi-parameter electrochemical sensing and lactate excretion rate analysis [0.03%]
基于多参数电化学传感和乳酸排泄率分析的汗液乳酸阈值心率监测
Wanting Lin,Tianhao Xue,Jiahui Zhou et al.
Wanting Lin et al.
Lactate is an important biomarker for assessing anaerobic metabolism and exercise intensity, and its continuous non-invasive monitoring is valuable for sports medicine and rehabilitation. However, sweat-based lactate sensing still faces two...
Comprehensive advances of microneedle technology in addressing diabetes mellitus and its multisystem complications [0.03%]
微针技术在糖尿病及其多系统并发症治疗中的全面进展
Huijia Song,Jiayi Liu,Yahui Zhang et al.
Huijia Song et al.
Diabetes mellitus (DM), a prevalent chronic metabolic disorder with a global prevalence over 10.5%, features persistent hyperglycemia-induced micro-/macro-vascular lesions and severe complications. Conventional DM management suffers from hi...
Duplex detection of anti-drug antibodies achieved by a spectrally resolved bioluminescence platform [0.03%]
一种通过光谱解析型生物发光平台实现的抗药物抗体双联检测法
Ruoxuan Sun,Xiaobin Zhang,Mark G Qian
Ruoxuan Sun
Bioluminescence (BL)-based biosensor represents a valuable and versatile analytical tool which offers high detection sensitivity and allows a streamlined, homogeneous workflow. However, nearly all existing BL assays are operated in a single...
Amplification-free detection of N6-Methyladenosine (m6A) based on droplet digital CRISPR-Cas13a [0.03%]
基于数字微滴CRISPR-Cas13a的无信号放大N6-甲基腺苷(m6A)检测方法
Chenfei Zhao,Xiao Liu,Ruiyang Sun et al.
Chenfei Zhao et al.
m6A (N6-methyladenosine), a prevalent RNA modification in eukaryotic mRNA involved in multiple biological processes, enables early cancer screening via its detection. m6A methylation detection is considered challenging, with most existing m...
Preparation of a new porous Zn-BTC loaded with Ag dendrites by two-step electrodeposition for SERS detection of tetracycline hydrochloride [0.03%]
一种新型银枝晶负载的Zn-BTC多孔材料的两步电沉积制备及盐酸四环素的表面增强拉曼检测
Dan Huang,Ling Li,Renjie Li et al.
Dan Huang et al.
Tetracycline hydrochloride (TCH) is a widely used antibiotic in animal husbandry and aquaculture practices, and its residual accumulation in food commodities constitutes a persistent public health concern. Therefore, sensitive, time-saving,...
ASCA-SHAP dual screening of PMI-related corneal ATR-FTIR spectral bands under temperature-dependent variation [0.03%]
基于温度依赖性变化的PMI相关角膜ATR-FTIR光谱带的ASCA-SHAP双筛查
Qiang Chen,Xuehong Qian,Erzhu Shao et al.
Qiang Chen et al.
The estimation of postmortem interval (PMI) is a long-standing scientific challenge in forensic pathology, and its accuracy is susceptible to environmental conditions. Environmental temperature can affect processes such as corneal tissue de...
Fluorescence lifetime imaging of G-quadruplex RNA dynamics in Alzheimer's disease using a novel nucleic acid-sensitive probe [0.03%]
用于阿尔茨海默病中G-四链体RNA动力学的新型核酸敏感探针的荧光寿命成像技术
Dong Wang,Wei Huang,Xiu Wang et al.
Dong Wang et al.
Real-time monitoring of G-quadruplex (G4) RNA dynamics is vital for understanding their biological roles in the progression and treatment of Alzheimer's disease. However, this remains challenging due to two key difficulties. First, current ...
Magnetic Janus nanofibrous composite membrane for green microextraction of BTEX from environmental samples [0.03%]
用于环境样品中BTEX绿色微萃取的磁性Janus纳米纤维素复合膜
Ali Taghavi,Hassan Sereshti
Ali Taghavi
Benzene, toluene, ethylbenzene, and xylene isomers (BTEX) are prominent pollutants of concern due to their adverse health effects and ubiquitous presence in environmental matrices. In this study, an innovative Janus nanocomposite membrane w...