Aline S Perez,Aleksandra T Morikawa,Raul C Maranhão et al.
Aline S Perez et al.
Cholesterol-rich nanoemulsion (LDE) can carry chemotherapeutic agents in the circulation and can concentrate those agents in the neoplastic and inflammatory tissues. This method improves the biodistribution of the drug and reduces toxicity....
Molecular insights into the interactions of theaflavin and epicatechin with different lipid bilayer membranes by molecular dynamics simulation [0.03%]
分子动力学模拟研究茶红素和表没食子儿茶素与不同脂质双层膜的相互作用机制
Rong-Zu Nie,Huo-Min Luo,Jing-Yu Chen et al.
Rong-Zu Nie et al.
At present, consumers increasingly favored the natural food preservatives with fewer side-effects on health. The green tea catechins and black tea theaflavins attracted considerable interest, and their antibacterial effects were extensively...
Jacob J Kinnun,Jan Michael Y Carrillo,C Patrick Collier et al.
Jacob J Kinnun et al.
Amantadine, a small amphilphic organic compound that consists of an adamantane backbone and an amino group, was first recognized as an antiviral in 1963 and received approval for prophylaxis against the type A influenza virus in 1976. Since...
The impact of phospholipids with high transition temperature to enhance redox-sensitive liposomal doxorubicin efficacy in colon carcinoma model [0.03%]
高相变温度磷脂增强还原敏感载多柔比星脂质体治疗结肠癌小鼠模型的作用机制研究
Elaheh Mirhadi,Anis Askarizadeh,Leila Farhoudi et al.
Elaheh Mirhadi et al.
In this study, we have developed a redox-sensitive (RS) liposomal doxorubicin formulation by incorporating 10,10'-diselanediylbis decanoic acid (DDA) organoselenium compound as the RS moiety. Hence, several RS liposomal formulations were pr...
A convenient method for the relative and absolute quantification of lipid components in liposomes by 1H- and 31P NMR-spectroscopy [0.03%]
一种通过氢和磷核磁共振光谱对脂质体中的脂质成分进行相对定量和绝对定量的简便方法
Andreas H Franz,Nataliya M Samoshina,Vyacheslav V Samoshin
Andreas H Franz
Objective: Liposomes are promising delivery systems for pharmaceutical applications and have been used in medicine in the recent past. Preparation of liposomes requires reliable characterization and quantification of the ...
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins [0.03%]
非层状热致液晶纳米粒作为封装钙立普妥和原花青素的纳米载体
Mardhiah Maslizan,Muhammad Salahuddin Haris,Mokrish Ajat et al.
Mardhiah Maslizan et al.
Atorvastatin calcium (ATV) and proanthocyanidins (PAC) have a strong antioxidant activity, that can benefit to reduce the atherosclerotic plaque progression. Unfortunately, the bioavailability of ATV is greatly reduced due to its limited dr...
Keisuke Matsuoka,Rina Sekiguchi,Tomokazu Yoshimura
Keisuke Matsuoka
The proportion of sodium taurolithocholate (NaTLC) is extremely low in human bile salts. NaTLC forms aggregates with other lipids in the bile and functions as an emulsifying and solubilizing agent. The molecular structure of NaTLC contains ...
Comparison of structural effects of cholesterol, lanosterol, and oxysterol on phospholipid (POPC) bilayers [0.03%]
胆固醇，羊毛固醇和氧化固醇对磷脂（POPC）双层结构影响的比较研究
Ayumi Okayama,Tatsuya Hoshino,Kohei Wada et al.
Ayumi Okayama et al.
Membrane sterols contribute to the function of biomembranes by regulating the physical properties of the lipid bilayers. Cholesterol, a typical mammalian sterol, is biosynthesized by oxidation of lanosterol. From a molecular evolutionary pe...
Harshit Kumar,Sayar Mandal,Reena Yadav et al.
Harshit Kumar et al.
Soluble alpha-amylases play an important role in the catabolism of polysaccharides. In this work, we show that the malt α -amylase can interact with the lipid membrane and further alter its mechanical properties. Vesicle fluctuation spectr...
The role of glucose and fructose on lipid droplet metabolism in human normal bronchial and cancer lung cells by Raman spectroscopy [0.03%]
拉曼光谱在人正常支气管和肺癌细胞中葡萄糖和果糖对脂滴代谢的作用研究
Monika Kopec,Karolina Beton-Mysur
Monika Kopec
Fructose is one of the most important monosaccharides in the human diet that the human body needs for proper metabolism. This paper presents an approach to study biochemical changes caused by sugars in human normal bronchial cells (BEpiC) a...