L Stefania Vargas-Velez,Natalia Wilke
L Stefania Vargas-Velez
Laurdan is a valuable tool for analyzing phase transitions and general behavior in synthetic lipid membranes. Its use is very straightforward, thus, its application in cells has expanded rapidly in recent years. It has been demonstrated tha...
Studying the interfacial activity and structure of pulmonary surfactant complexes [0.03%]
肺表面活性剂复合物的界面活性及结构研究
Ainhoa Collada,Antonio Cruz,Jesús Pérez-Gil
Ainhoa Collada
Pulmonary surfactant (PS) is a membranous complex that coats the respiratory air-liquid interface in air-breathing animal lungs. Its main function is to minimize the surface tension at the end of expiration, what is needed for preventing al...
Use of stable isotope-labeled fatty acids to measure desaturase activities with negative chemical ionization GC-MS [0.03%]
利用化学离子法GC-MS测量去饱和酶活性的稳定同位素标记脂肪酸的方法研究
Youenn Launay,Iwan Jan,Vincent Ciesielski et al.
Youenn Launay et al.
Fatty acid desaturases are key enzymes in lipid metabolism. They introduce double bonds between defined carbons of the fatty acyl chain and catalyze rate-limiting steps in the biosynthesis of polyunsaturated fatty acids. For decades, in vit...
Evidence for capture of spin-labeled ibuprofen drug molecules by lipid rafts in model membranes [0.03%]
有关模型膜中脂筏捕获带自旋标记的布洛芬药物分子的证据
Elena A Golysheva,Denis S Baranov,Sergei A Dzuba
Elena A Golysheva
Lipid rafts are lipid-cholesterol nanostructures thought to exist in cell membranes, which are characterized by higher ordering compared to their surroundings. Ibuprofen and other non-steroidal anti-inflammatory drugs (NSAIDs) have a high a...
Exploring the orphan immune receptor TREM2 and its non-protein ligands: In silico characterization [0.03%]
孤儿免疫受体TREM2及其非蛋白配体的计算表征研究
Pedro Henrique Dos Santos Dantas,Vinícius Alexandre Fiaia Costa,Andrei Giacchetto Felice et al.
Pedro Henrique Dos Santos Dantas et al.
The triggering receptor expressed on myeloid cells 2 (TREM2) is an immunoreceptor that interacts with a wide range of non-protein ligands, and it has been implicated in infectious and non-infectious diseases. However, there is a limited und...
Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane [0.03%]
脂质组成及其对皮肤膜结构和动态性质影响的分子动力学模拟研究
Diyar Altun,Per Larsson,Christel A S Bergström et al.
Diyar Altun et al.
The stratum corneum (SC) plays the most important role in the absorption of topical and transdermal drugs. In this study, we developed a multi-layered SC model using coarse-grained molecular dynamics (CGMD) simulations of ceramides, cholest...
Comparison between statistical and machine learning methods to detect the hematological indices with the greatest influence on elevated serum levels of low-density lipoprotein cholesterol [0.03%]
统计方法与机器学习方法检测血细胞指数中对低密度脂蛋白胆固醇血症影响最大的指数的比较分析
Somayeh Ghiasi Hafezi,Bahareh Behkamal,Mohammad Rashidmayvan et al.
Somayeh Ghiasi Hafezi et al.
Introduction: Elevated levels of low-density lipoprotein-cholesterol (LDL-C) is a significant risk factor for the development of cardiovascular diseases (CVD)s. Furthermore, studies have revealed an association between in...
Comparative Study
Chemistry and physics of lipids. 2024 Nov:265:105446. DOI:10.1016/j.chemphyslip.2024.105446 2024
Rapid screening of prednisolone acetate adulterants in health foods using colloidal gold immunochromatographic assay [0.03%]
一种快速检测保健食品中醋酸可的松掺杂物的胶体金免疫层析方法
Sayed Haidar Abbas Raza,Zixin Huang,Yimeng Pang et al.
Sayed Haidar Abbas Raza et al.
In this study, a rapid detection method utilizing colloidal gold immunochromatography (CG-ICA) was developed for the detection of illegally added prednisone acetate in health foods. Initially, the preparation conditions of colloidal gold so...
Effect of phosphatidylcholine regioisomerism on lateral segregation of milk sphingomyelin in bilayer membranes [0.03%]
卵磷脂区域异构体对乳鞘氨醇磷脂双分子层膜侧向分相的影响研究
Md Abdullah Al Sazzad,Max Lönnfors,Baoru Yang
Md Abdullah Al Sazzad
Milk fat globule membrane (MFGM) promotes the lateral phase separation of milk lipids and stabilizes the fat globules in milk. The composition and structures of lipids have a significant impact on physicochemical properties of MFGM, which i...
Effect of polyphenolic dendrimers on biological and artificial lipid membranes [0.03%]
多酚型树状分子对生物和人工脂质膜的影响
Marika Grodzicka,Sylwia Michlewska,Adam Buczkowski et al.
Marika Grodzicka et al.
The use of dendrimers as nanovectors for nucleic acids or drugs requires the understanding of their interaction with biological membranes. This study investigates the impact of 1st generation polyphenolic carbosilane dendrimers on biologica...