The reverse sequence of Aβ amyloid self-triggers isolated nano-fibers and oligomers in lipid environment [0.03%]
Aβ淀粉样蛋白的逆序序列在脂质环境中自我触发孤立的纳米纤维和寡聚体
Alain Bolaño Alvarez,María Elisa Mariani,Pablo E A Rodríguez et al.
Alain Bolaño Alvarez et al.
Nanostructured lipid/peptide film at air/water interface allow to build different molecular arrangements depending of peptide sequence, peptide proportion and type of lipid. We studied the surface properties of Aβ(1-42) and its retro-isome...
Bending the rules: molecular dynamics of hydroxylated sphingolipid membranes with 2-hydroxyoleic acid [0.03%]
打破规则：含有2-羟基油酸的羟基鞘脂膜的分子动力学研究
Lucia Sessa,Simona Concilio,Miriam Di Martino et al.
Lucia Sessa et al.
In this study, we introduce a novel method for quantifying the mechanical properties of lipid membranes-bending rigidity (κ), Gaussian rigidity (κG), and surface tension (γ) using molecular dynamics (MD) simulations. Our approach is appl...
Luis Fernando do Carmo Morato,Gilia Cristine Marques Ruiz,Carlos Junior Amorim Lessa et al.
Luis Fernando do Carmo Morato et al.
The increased use of agrochemicals in crop production raises concerns about the risk of combined pesticide exposure through water and food, potentially leading to a 'cocktail effect' with synergistic impacts on human health. To investigate ...
Interaction of biomimetic lipid membranes with detergents with different physicochemical characteristics [0.03%]
仿生脂质膜与不同理化性质的去垢剂相互作用
Mariana S S Oliveira,Amanda C Caritá,Karin A Riske
Mariana S S Oliveira
Membrane solubilization by detergents is routinely performed to separate membrane components, and to extract and purify membrane proteins. This process depends both on the characteristics of the detergent and properties of the membrane. Her...
Broad-based targeted lipidomic analysis of dental fluorosis population in an adult population [0.03%]
成人氟斑牙患者血浆脂质组学分析
Huiying Kong,Shanshan Liu,Zhenzhen Li et al.
Huiying Kong et al.
Dental fluorosis, as a common chronic fluoride toxicity oral disease, is mainly caused by long-term excessive intake of fluoride, which seriously affects the aesthetics and function of patients' teeth. In recent years, with the rapid develo...
Electrophysiological dissection of the ion channel activity of the Pseudomonas aeruginosa ionophore protein toxin Tse5 [0.03%]
伪单胞菌属嗜污菌离子载体蛋白毒素Tse5的离子通道活性的电生理分析
Jessica Rojas-Palomino,Jon Altuna-Alvarez,Amaia González-Magaña et al.
Jessica Rojas-Palomino et al.
We present an in-depth electrophysiological analysis of Tse5, a pore-forming toxin (PFT) delivered by the type VI secretion system (T6SS) of Pseudomonas aeruginosa. The T6SS is a sophisticated bacterial secretion system that injects toxic e...
Effect of hydrophobic proteins in modulating the mechanical properties of lung surfactant membranes [0.03%]
疏水蛋白调节肺表面活性膜机械性能的作用
Ainhoa Collada,Johann Mertens,Emma Batllori-Badia et al.
Ainhoa Collada et al.
Pulmonary surfactant is a membranous complex that enables breathing dynamics at the respiratory surface. Extremely low values of surface tension are achieved at end-expiration thanks to a unique mixture of lipids and proteins. In particular...
Modifications of biological membranes, fat globules and liposomes promoted by cavitation processes. Consequences and applications [0.03%]
空化过程促进的生物膜、脂肪球和脂质体的改良及其后果与应用
Santiago Fleite,Miryan Cassanello,María Del Pilar Buera
Santiago Fleite
Cavitation-based technologies, such as ultrasound (or acoustic cavitation, AC) and hydrodynamic cavitation (HC), are gaining interest among green processing technologies due to their cost effectiveness in operation, toxic solvent use reduct...
The mechanical properties of nerves, the size of the action potential, and consequences for the brain [0.03%]
神经的机械特性，动作电位的大小以及对大脑的影响
Thomas Heimburg
Thomas Heimburg
The action potential is widely regarded as a purely electrical phenomenon. However, one also finds mechanical and thermal changes that can be observed experimentally. In particular, nerve membranes become thicker and axons contract. The spa...
Francisco J Barrantes
Francisco J Barrantes
Millions of years of phylogenetic evolution have shaped the crosstalk between sterols and membrane-embedded proteins. This lengthy process, which began before the appearance of eukaryotic cells, has sculpted the two types of molecules to co...