Lipid-based nanocarriers for antiviral drug delivery: A review of the advances, manufacturing technologies, therapeutic mechanisms, and clinical applications [0.03%]
用于抗病毒药物递送的脂质基纳米载体：进展、制造技术、治疗机制和临床应用综述
Heena Maithania,Pooja Tiwary,Krishil Oswal et al.
Heena Maithania et al.
Background: The persistent global burden of viral infections, compounded by the emergence of resistance and suboptimal therapeutic efficacy, underscores the urgency for innovative treatment strategies. Recent viral outbre...
The influence of dihydroquercetin on the cell membrane model of Clavibacter michiganensis subsp. sepedonicus [0.03%]
茋的同分异构体二氢槲皮素对马铃薯碎脐病菌细胞膜模型的影响研究
Jin Cai,Xingyuan Gao,Shiqin Wang
Jin Cai
Dihydroquercetin (DHQ) exhibited antimicrobial activity associated with its interaction with bacterial cell membranes. However, molecular-level mechanism has not been revealed. Therefore, this study investigated the potential interactions b...
Effects of silver nanoparticles on the morphology and membrane permeability of giant unilamellar vesicles and their mechanistic insights [0.03%]
银纳米颗粒对大单层脂质体形态和膜通透性影响及其作用机制研究
Zarin Tasnim Rakhy,Tawfika Nasrin,Mir Jubair Ahamed et al.
Zarin Tasnim Rakhy et al.
Silver nanoparticles (AgNPs) are extensively used in healthcare, medicine, and environmental fields owing to their strong antiviral and antibacterial properties. Although these NPs interact with cellular biomembranes or vesicular lipid memb...
Molecular dynamics deciphers drug-dependent stability in therapeutic liposomes [0.03%]
基于药物依赖稳定性的治疗脂质体的分子动力学研究
F Rostami,D M Aghaie,O Bavi
F Rostami
Liposomal stability is critical for effective drug delivery, yet its dependence on drug-membrane interactions remains incompletely understood. Here, we employ atomic-scale molecular dynamics simulations to investigate the structural stabili...
A comparison of the effect of SMA derivatives on the structural topology and dynamics of two bacteriophage peptides [0.03%]
SMA衍生物对两种噬菌体肽的结构拓扑和动力学的影响比较
Nancy C Rotich,Evelyn A Okorafor,Indra D Sahu et al.
Nancy C Rotich et al.
Researchers have explored and cultivated suitable membrane mimetics to preserve a physiological solvent condition for membrane protein functions. This involves emulating the properties of lipid bilayers, particularly within the hydrophobic ...
Sources and biological functions of nervonic acid: Advances and perspectives [0.03%]
神经酸的来源及生物学功能：进展与展望
Yihe Li,Xiaolong Gao,Zhuoao Gao et al.
Yihe Li et al.
Nervonic Acid (NA), as a critical component of neural myelin sheaths, maintains nerve cell structural integrity and function. Due to limited synthesis in humans, it is primarily obtained through plant extraction, chemical synthesis, or bios...
Corrigendum to "Effect of the CER[NP]:CER[AP] a ratio on the structure of a stratum corneum model lipid matrix - a molecular dynamics study" [Chem. Phys. Lipid. 250 (2023) 105259] [0.03%]
“CERNP:CERAP比率对角质层模型脂质矩阵结构的影响——分子动力学研究”一文的勘误[发表于《化学与物理学报 lipid》第250期（2023年）105259页]
Natalia Rivero,Martha C Daza,Markus Doerr
Natalia Rivero
Coexistence of Domains Composed of Intercellular Lipids in Stratum Corneum as Studied by X-Ray Diffraction and Differential Scanning Calorimetry [0.03%]
用X射线衍射和差示扫描量热法研究角质层中由细胞间脂质组成的共存域
Ichiro Hatta,Yoshitomo Furushima,Masaru Nakada et al.
Ichiro Hatta et al.
The intercellular lipid matrix of stratum corneum is composed of many lipid components, including ceramides, free fatty acids, and cholesterol, which nonetheless form regularly arranged structures; short- and long-period lamellar structures...
Branched-chain fatty acids with different structure exhibit distinct anti-hepatoma activities and characteristics [0.03%]
不同结构的支链脂肪酸抗肝癌活性及特点不同
Yaqi Huang,Houyue Li,Jialing Gu et al.
Yaqi Huang et al.
Branched-chain fatty acids (BCFAs) exhibit potential anticancer activity, but their systematic evaluation and comparison with straight-chain saturated fatty acids (SSFAs) remain limited due to monomer accessibility issues. This study utiliz...
Cholesterol and related sterols differentially modulate lipid domain dynamics in model membranes: a dual-probe analysis of domain-specific effects [0.03%]
胆固醇及其相关固醇通过双探针分析模型膜中脂质区域的特定效应差异调节脂质域动力学
Jesus Ayala-Sanmartin,Antonin Lamazière
Jesus Ayala-Sanmartin
The role of cholesterol in the organization and ordering of membrane domains has been well established over the past decades. However, the involvement of cholesterol precursors and byproduct sterols in modulating the physicochemical propert...