The shape and free energy of a lipid bilayer surrounding a membrane inclusion [0.03%]
包含膜结构的脂质双层的形状和自由能
Richard Tjörnhammar,Olle Edholm
Richard Tjörnhammar
Membrane inclusion interactions are studied within the scope of continuum theory. We show that the free energy functional for the membrane thickness can be rewritten as a constant times a dimensionless integral. For cylindrical inclusions, ...
Isolation of giant unilamellar vesicles from electroformed vesicle suspensions and their extrusion through nano-pores [0.03%]
通过电形成的大单层囊泡的分离及其通过纳米孔道的挤出
Yogita P Patil,Amanpreet Kaur Ahluwalia,Sameer Jadhav
Yogita P Patil
Liposomes required for drug delivery are commonly obtained by extrusion of phospholipid vesicle suspensions through track-etched membranes. The effects of trans-membrane pressure, membrane pore size and bilayer composition on extruded lipos...
Probing microscopic material properties inside simulated membranes through spatially resolved three-dimensional local pressure fields and surface tensions [0.03%]
通过空间解析的三维局部压力场和表面张力探究模拟膜内部的微观材料性质
Peter M Kasson,Berk Hess,Erik Lindahl
Peter M Kasson
Cellular lipid membranes are spatially inhomogeneous soft materials. Materials properties such as pressure and surface tension thus show important microscopic-scale variation that is critical to many biological functions. We present a means...
How sterol tilt regulates properties and organization of lipid membranes and membrane insertions [0.03%]
胆固醇倾斜对脂质膜和膜插入物的性质及组织的影响机制研究
George Khelashvili,Daniel Harries
George Khelashvili
Serving as a crucial component of mammalian cells, cholesterol critically regulates the functions of biomembranes. This review focuses on a specific property of cholesterol and other sterols: the tilt modulus χ that quantifies the energeti...
Peter M Macdonald,Qasim Saleem,Angel Lai et al.
Peter M Macdonald et al.
Lateral diffusion is a fundamental property of biological membrane components, important for a host of biomembrane functions. Although long studied, novel aspects of the relationship between the structure of membrane components and their la...
A highly sensitive quantification of phytosterols through an inexpensive derivatization [0.03%]
一种高灵敏的植物甾醇衍生化定量方法
Songbai Liu,Huina Ruan
Songbai Liu
A highly sensitive method for quantification of phytosterols based on HPLC has been developed by derivatization with the benzoyl chromophore. Introduction of the chromophore, benzoyl group, to phytosterols via simple and inexpensive derivat...
An Li,Binfang Yuan,Weiming Li et al.
An Li et al.
The molecular mechanisms of the thermally induced cis/trans isomerization of the non-conjugated linoleic acids (C18:2) were investigated in a combined experimental and computational study of C18:2 isomers. C18:2 isomers in soybean oil heate...
The basis of the substrate specificity of the epsilon isoform of human diacylglycerol kinase is not a consequence of competing hydrolysis of ATP [0.03%]
人ε型二酰基甘油激酶底物特异性的基础并非由ATP竞争性水解所导致
Aaron Prodeus,Bob Berno,Matthew K Topham et al.
Aaron Prodeus et al.
The diacylglycerol kinase from E. coli transfers some of the γ-phosphate of ATP to water as well as to diacylglycerol. We also demonstrate that glycerol can act as an acceptor for the phosphate of ATP. We have compared this behavior with t...
Recruitment of a phospholipase C/sphingomyelinase into non-lamellar lipid droplets during hydrolysis of lipid bilayers [0.03%]
在脂质双层水解过程中，磷脂酶C/鞘磷脂酶募集到非层状脂滴中
Maitane Ibarguren,Jesús Sot,L Ruth Montes et al.
Maitane Ibarguren et al.
When giant unilamellar vesicles (GUVs) composed of sphingomyelin, phosphatidylcholine, phosphatidylethanolamine, and cholesterol are treated with PlcHR(2), a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa, the initial stages o...
Partitioning of ethanol in multi-component membranes: effects on membrane structure [0.03%]
乙醇在多组分膜中的分离对膜结构的影响
Anirban Polley,Satyavani Vemparala
Anirban Polley
The molecular mechanism of ethanol and its effects on neurological function is far from clear. In this study, we investigate the effects of ethanol on various structural and dynamical properties of mixed bilayers consisting of different rat...