Reducing inappropriate vitamin D testing: an analysis of three sequential diagnostic stewardship interventions and the carbon footprint implications [0.03%]
减少不适当的维生素D检测：三种连续诊断药物管理干预措施分析及其碳足迹影响
C Hughes,M A Myers,M Tickell-Painter et al.
C Hughes et al.
Introduction: The climate crisis is a health crisis, and healthcare contributes to this via consumption of resources, the release of greenhouse gases, and the generation of waste. Pathology testing underpins most healthca...
Diagnostic accuracy of biomarkers for irritable bowel syndrome: a systematic review and meta-analysis [0.03%]
生物标志物诊断肠易激综合征准确性的系统评价和meta分析
Jianjiao Mou,Qingfeng Tao,Lu Xu et al.
Jianjiao Mou et al.
This study aimed to systematically assess the diagnostic performance of multiple biomarkers for irritable bowel syndrome (IBS). Systematic electronic searches were conducted in PubMed, Cochrane Central Register of Controlled Trials, Embase,...
Association of hypertension and genetic variants in MYH9 and BMPR1B with increased proteinuria in sickle cell disease [0.03%]
高血压、MYH9和BMPR1B基因多态性与镰状细胞病蛋白尿的关系
El Hadji Malick Ndour,Kuthala Mnika,El Hadj Ousmane Sene et al.
El Hadji Malick Ndour et al.
Background: Sickle cell nephropathy (SCN) is a major chronic complication of sickle cell disease, and its progression may be influenced by genetic factors. This study aimed to investigate the association between variants ...
Analytical imprecision and therapeutic intervals for lithium - Are there Implications for old age patients with bipolar disorder? [0.03%]
锂分析不精确与治疗窗口：会对老年期发病双相情感障碍患者产生影响吗？
Janet Zhou,Demitra Tsoukalas,Nethra Chittiprol et al.
Janet Zhou et al.
Background: Monitoring blood levels of lithium is important for maintaining therapeutic efficacy. Age-dependent therapeutic intervals have been recommended by the International Society for Bipolar Disorder (ISBD) task for...
A case of late-onset carbamoyl phosphate synthetase 1 deficiency: diagnostic challenges and management in a low-resource setting [0.03%]
一例迟发型氨甲磷酸合成酶缺乏症的诊疗挑战及资源匮乏地区的管理措施
Xiaopu Cui,Sixian Guo,Yu Zhang et al.
Xiaopu Cui et al.
Objective: This study aimed to analyze the clinical features, genetic basis, and management of late-onset carbamoyl phosphate synthetase 1 deficiency (CPS1D) through a pediatric case report and literature review, highligh...
Pre-Analytical Considerations in the simultaneous quantification of Ketone Bodies, Lactate, pyruvate and TCA cycle intermediates [0.03%]
血酮体、乳酸、丙酮酸和三羧酸循环中间产物的同步定量的前分析考虑因素
Kaitlyn Berchier,Chiara Nyffeler,Stephen Bruce et al.
Kaitlyn Berchier et al.
Background: Accurate quantification of small metabolites such as ketone bodies (KB: β-hydroxybutyrate (BHB), acetoacetate (AcAc)), pyruvate (Pyr), lactate (Lac) and tricarboxylic acid (TCA) cycle intermediates is essenti...
Change in cardiac troponin T to differentiate acute from chronic myocardial injury in the Emergency Department [0.03%]
急诊科运用心肌抑制蛋白T定性急性与慢性心肌损伤的改变
Bertil Lindahl,Alexander Jf Thurston,Yong Yong Tew et al.
Bertil Lindahl et al.
Introduction: Persistently elevated cardiac troponin (cTn) values are observed in many patients with suspected acute coronary syndrome (ACS) in the absence of myocardial infarction and may reflect underlying cardiac disea...
Stanislas Francois,Sreekanth Rajagopal,Anne Boutten et al.
Stanislas Francois et al.
Hypokalemia is a relatively common electrolyte disturbance that, despite its frequency, can pose a serious threat when it occurs in patients with end-stage chronic illnesses. In many individuals, mild to moderate reductions in serum potassi...
Incorrectly prepared formula contributing to severe hypovolemic hypernatremia in enteral tube-fed children: A report of two cases [0.03%]
配方不当所致早发婴儿肠内喂养严重低血容量性高钠血症两例报告
Lawrence de Koning,Shelina M Jamal,Catherine Ross et al.
Lawrence de Koning et al.
Case presentations: We describe two cases of children who were significantly impacted by incorrectly prepared, hyperosmolar formula delivered via enteral tubes. The first case is of a 5-month-old post-pancreatectomy patie...
A tale of two variants: The first reported case of hemoglobin Rush and hemoglobin S in a compound heterozygote [0.03%]
两种变异型珠蛋白病的病例报道：首例复合杂合子Hb Rush和Hb S患者的报告
Amanda Cristina Meneguetti Berti,Bárbara Braga Vieira Marques,Victoria Simões Bernardo et al.
Amanda Cristina Meneguetti Berti et al.
Hemoglobinopathies are among the most common inherited disorders worldwide, caused by various mutations in the hemoglobin (Hb) genes. These mutations can lead to different clinical outcomes, some of which cause significant symptoms, highlig...